Development Level

Tbio 9 | 11,651
Tchem 8 | 1,388
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal body wall morphology 1 | 9
abnormal duodenum morphology 1 | 4
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal facial morphology 1 | 17
abnormal limb bud morphology 1 | 17
abnormal limb morphology 1 | 13
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal tail morphology 1 | 25
abnormal vibrissa morphology 1 | 25
brachydactyly 1 | 19
cleft palate 1 | 8
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased respiratory quotient 1 | 16
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
hemorrhage 1 | 23
hypoactivity 1 | 132
increased total body fat amoun... 1 | 134

Disease

psoriasis 11 | 6,694
Carcinoma 10 | 11,493
ovarian cancer 10 | 8,520
pituitary cancer 10 | 1,972
lung carcinoma 6 | 2,843
medulloblastoma, large-cell 6 | 6,241
osteosarcoma 6 | 7,950
pancreatic cancer 6 | 2,398
Alzheimer's disease 5 | 658
Cancer 5 | 2,499
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung cancer 5 | 4,740
malignant mesothelioma 5 | 3,232
subependymal giant cell astrocytoma 5 | 2,287
Autosomal recessive predisposition 4 | 1,442
Breast cancer 4 | 3,578
Hypertension 4 | 396
Multiple Sclerosis 4 | 540
atypical teratoid / rhabdoid tumor 4 | 5,112
diabetes mellitus 4 | 1,728
ependymoma 4 | 4,679
glioblastoma 4 | 5,792
group 3 medulloblastoma 4 | 4,104
lung adenocarcinoma 4 | 2,716
oligodendroglioma 4 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Abnormality of metabolism/homeostasis 3 | 134
Alcoholic Intoxication, Chronic 3 | 289
Constipation 3 | 181
Down syndrome 3 | 499
Hypertensive disease 3 | 292
Hypogonadism 3 | 173
Infertility 3 | 188
Pick disease 3 | 1,894
Polycystic ovary syndrome 3 | 360
active Crohn's disease 3 | 922
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
posterior fossa group A ependymoma 3 | 468
spina bifida 3 | 1,074
ulcerative colitis 3 | 1,819
Acquired metabolic disease 2 | 336
Adenoma 2 | 167
Alcoholism 2 | 45
Amenorrhea 2 | 58
Amyotrophic lateral sclerosis 2 | 451
Atherosclerosis 2 | 291
Atopic dermatitis 2 | 952
Bipolar Disorder 2 | 666
Bradycardia 2 | 36
Cerebrovascular disease 2 | 238
Cholestasis 2 | 155
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Dyschezia 2 | 135
Female infertility 2 | 30
Fever 2 | 138
Gynecomastia 2 | 64
Heart disease 2 | 306
Hyperphagia 2 | 23
Hyperprolactinemia 2 | 27
Hyperthyroidism 2 | 53
Hypogonadism, Isolated Hypogonadotropic 2 | 71
Hypogonadotropic hypogonadism 2 | 89
Hypopigmentation disorder 2 | 25
Hypopituitarism 2 | 40
Hypothyroidism 2 | 122
Increased appetite (finding) 2 | 23
Infertility, Female 2 | 28
Infertility, Male 2 | 46
Kidney Diseases 2 | 114
Kidney cancer 2 | 2,613
Kidney disease 2 | 430
Klinefelter's syndrome 2 | 56
Male infertility 2 | 206
Melanoma 2 | 711
Motion sickness 2 | 21
Oligospermia 2 | 36
Pain agnosia 2 | 104
Pituitary adenoma 2 | 38
Primary physiologic amenorrhea 2 | 55
Sparse axillary hair 2 | 28
Sparse pubic hair 2 | 31
Ventricular Septal Defects 2 | 119
Weight decreased 2 | 103
aldosterone-producing adenoma 2 | 665
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis 2 | 1,696
ductal carcinoma in situ 2 | 1,745
fibroadenoma 2 | 559
glioblastoma multiforme 2 | 142
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
invasive ductal carcinoma 2 | 2,951
mucosa-associated lymphoid tissue lymphoma 2 | 484
nasopharyngeal carcinoma 2 | 1,058
non-small cell lung cancer 2 | 2,890
primitive neuroectodermal tumor 2 | 3,035
tuberculosis 2 | 2,010

Tissue

Blood and immune system 17 | 16,909
Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Nervous System 17 | 16,725
Respiratory system 17 | 16,393
Skin and soft tissues 17 | 17,230
Urinary Tract 16 | 16,678
Male tissues 15 | 17,142
Cardiovascular System 14 | 15,192

Target Family

Enzyme 9 | 4,145
Non-IDG 9 | 12,091

GO Process

peptide hormone processing 18 | 18
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-secretase 2 BACE2 Tchem Enzyme -2.09709 114.0 418
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Proprotein convertase subtilisin/kexin type 6 PCSK6 Tchem Enzyme -2.33983 216.4 239
Pro-opiomelanocortin POMC Tbio Non-IDG -4.56004 36591.2 1334
Atrial natriuretic peptide-converting enzyme CORIN Tbio Non-IDG -2.14443 144.4 221
Neuroendocrine convertase 2 PCSK2 Tchem Enzyme -2.00248 109.8 132
Choriogonadotropin subunit beta 3 CGB8 Tdark Non-IDG -1.92082 114.7 0
Lutropin subunit beta LHB Tbio Non-IDG -2.74538 538.1 502
Follitropin subunit beta FSHB Tbio Non-IDG -2.18224 143.3 599
Thyrotropin subunit beta TSHB Tbio Non-IDG -2.65550 431.2 787