Development Level

Tbio 9 | 10,625
Tchem 7 | 1,890

IMPC Term

preweaning lethality, complete... 2 | 633
abnormal body wall morphology 1 | 7
abnormal duodenum morphology 1 | 1
abnormal embryo size 1 | 112
abnormal eye morphology 1 | 38
abnormal facial morphology 1 | 9
abnormal limb bud morphology 1 | 15
abnormal limb morphology 1 | 7
abnormal lung morphology 1 | 15
abnormal neural tube closure 1 | 37
abnormal tail morphology 1 | 17
abnormal vibrissa morphology 1 | 17
brachydactyly 1 | 2
cleft palate 1 | 6
embryonic growth retardation 1 | 28
embryonic lethality prior to t... 1 | 187
hemorrhage 1 | 12
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
oligodactyly 1 | 14
preweaning lethality, incomple... 1 | 260

Disease

psoriasis 10 | 6,685
ovarian cancer 9 | 8,484
pituitary cancer 9 | 1,972
osteosarcoma 6 | 7,933
Alzheimer's disease 5 | 644
interstitial cystitis 5 | 2,299
lung cancer 5 | 4,466
lung carcinoma 5 | 2,844
malignant mesothelioma 5 | 3,162
medulloblastoma, large-cell 5 | 6,234
pancreatic cancer 5 | 2,300
Cancer 4 | 2,346
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
lung adenocarcinoma 4 | 2,713
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
posterior fossa group A ependymoma 4 | 1,511
subependymal giant cell astrocytoma 4 | 2,287
ulcerative colitis 4 | 2,087
Breast cancer 3 | 3,094
Carcinoma 3 | 2,147
Down syndrome 3 | 548
Hypertension 3 | 287
Hypertensive disease 3 | 193
Hypogonadism 3 | 70
Infertility 3 | 163
Klinefelter's syndrome 3 | 59
Pick disease 3 | 1,893
Polycystic Ovary Syndrome 3 | 332
active Crohn's disease 3 | 918
diabetes mellitus 3 | 1,663
glioblastoma 3 | 5,572
group 4 medulloblastoma 3 | 1,875
oligodendroglioma 3 | 2,849
spina bifida 3 | 1,064
Acquired metabolic disease 2 | 267
Adenoma 2 | 165
Alcoholic Intoxication, Chronic 2 | 41
Amenorrhea 2 | 60
Atopic dermatitis 2 | 944
Bipolar Disorder 2 | 266
Body Weight 2 | 14
Bradycardia 2 | 24
Cerebrovascular disease 2 | 231
Diabetes insipidus 2 | 14
Female infertility 2 | 28
Fever 2 | 34
Heart disease 2 | 279
Hyperprolactinemia 2 | 22
Hyperthyroidism 2 | 50
Hypopituitarism 2 | 36
Hypothermia, natural 2 | 12
Hypothyroidism 2 | 89
Kidney Diseases 2 | 86
Leydig cell tumor 2 | 9
Male infertility 2 | 170
Multiple Sclerosis 2 | 498
Obesity 2 | 616
Oligospermia 2 | 30
Pain agnosia 2 | 99
Pituitary adenoma 2 | 35
Schizophrenia 2 | 501
astrocytic glioma 2 | 2,241
atypical teratoid / rhabdoid tumor 2 | 4,369
breast carcinoma 2 | 1,614
cystic fibrosis 2 | 1,665
ductal carcinoma in situ 2 | 1,745
fibroadenoma 2 | 557
glioblastoma multiforme 2 | 347
group 3 medulloblastoma 2 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
invasive ductal carcinoma 2 | 2,950
mucosa-associated lymphoid tissue lymphoma 2 | 480
nasopharyngeal carcinoma 2 | 1,056
non-small cell lung cancer 2 | 2,798
pediatric high grade glioma 2 | 2,712
posterior fossa group B ependymoma 2 | 1,530
Adrenal cortical adenoma 1 | 10
Amnesia 1 | 17
Anxiety disorder 1 | 22
Bone Diseases, Developmental 1 | 25
Carney complex 1 | 23
Congenital hypothyroidism 1 | 20
Craniopharyngioma 1 | 13
Cystitis 1 | 16
Disorder of eye 1 | 7
Empty sella syndrome 1 | 6
Facial paralysis 1 | 15
Frozen shoulder 1 | 6
Heart Septal Defects 1 | 2
Hemorrhage 1 | 18
Jaw Abnormalities 1 | 5
Lower Extremity Deformities, Congenital 1 | 2
Neurogenic Inflammation 1 | 12
Neurohypophyseal diabetes insipidus 1 | 13
Personality disorder 1 | 25
Seborrheic dermatitis 1 | 19
Splenic infarction 1 | 6
Substance abuse 1 | 55
Tenosynovitis 1 | 15
Thyroiditis 1 | 25

Tissue

Blood and immune system 16 | 17,995
Cardiovascular System 16 | 17,958
Digestive Tract 16 | 18,473
Endocrine System 16 | 18,512
Female tissues 16 | 18,647
Liver and Pancreas 16 | 18,136
Nervous System 16 | 18,561
Skin and soft tissues 16 | 18,115
Urinary Tract 16 | 18,444
Male tissues 15 | 17,969
Respiratory system 15 | 17,484

Target Family

Enzyme 8 | 4,146
Non-IDG 8 | 11,971

GO Process

peptide hormone processing 16 | 16
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lutropin subunit beta LHB Tbio Non-IDG -2.65527 470.5 360
Follitropin subunit beta FSHB Tbio Non-IDG -2.16001 147.2 437
Thyrotropin subunit beta TSHB Tbio Non-IDG -2.64322 424.0 492
Glycoprotein hormones alpha chain CGA Tbio Non-IDG -2.58010 384.5 708
Pro-opiomelanocortin POMC Tbio Non-IDG -4.54944 36028.8 1100
ProSAAS PCSK1N Tbio Non-IDG -2.20337 169.4 66
Beta-secretase 2 BACE2 Tchem Enzyme -2.07093 112.3 369
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.52889 336.7 241
Atrial natriuretic peptide-converting enzyme CORIN Tbio Non-IDG -2.07994 129.6 179
Proprotein convertase subtilisin/kexin type 5 PCSK5 Tchem Enzyme -2.83840 697.2 118