Development Level

Tdark 23 | 7,003
Tbio 20 | 10,625
Tchem 6 | 1,890

IMPC Phenotype

abnormal bone structure 2 | 131
abnormal rib morphology 2 | 28
decreased circulating insulin ... 2 | 75
enlarged heart 2 | 111
improved glucose tolerance 2 | 56
abnormal heart morphology 1 | 51
abnormal kidney morphology 1 | 30
abnormal liver morphology 1 | 5
abnormal lung morphology 1 | 15
abnormal seminal vesicle morph... 1 | 47
abnormal thoracic vertebrae mo... 1 | 16
abnormal vibrissa morphology 1 | 17
cardiovascular system phenotyp... 1 | 35
decreased body length 1 | 108
decreased circulating serum al... 1 | 79
decreased lumbar vertebrae num... 1 | 62
decreased rib number 1 | 59
decreased thoracic vertebrae n... 1 | 7
increased bone mineral content 1 | 92
increased fasted circulating g... 1 | 68
increased heart rate variabili... 1 | 4
increased sacral vertebrae num... 1 | 62
male infertility 1 | 62
persistence of hyaloid vascula... 1 | 22
preweaning lethality, incomple... 1 | 260

Disease

psoriasis 26 | 6,685
diabetes mellitus 16 | 1,663
ovarian cancer 13 | 8,491
esophageal adenocarcinoma 12 | 737
lung cancer 11 | 4,473
osteosarcoma 11 | 7,933
Atopic dermatitis 10 | 944
cystic fibrosis 10 | 1,670
medulloblastoma, large-cell 10 | 6,234
nasopharyngeal carcinoma 10 | 1,056
pancreatic cancer 9 | 2,300
glioblastoma 7 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
non-small cell lung cancer 7 | 2,798
Cancer 6 | 2,346
Carcinoma 6 | 2,147
interstitial cystitis 6 | 2,299
lung carcinoma 6 | 2,844
malignant mesothelioma 6 | 3,163
Breast cancer 5 | 3,098
atypical teratoid / rhabdoid tumor 5 | 4,369
ductal carcinoma in situ 5 | 1,745
invasive ductal carcinoma 5 | 2,950
lung adenocarcinoma 5 | 2,714
primary pancreatic ductal adenocarcinoma 5 | 1,271
ulcerative colitis 5 | 2,087
Becker muscular dystrophy 4 | 187
Congenital ichthyosiform erythroderma 4 | 27
Duchenne muscular dystrophy 4 | 602
Ichthyosis vulgaris 4 | 15
Squamous cell carcinoma 4 | 96
breast carcinoma 4 | 1,614
cutaneous lupus erythematosus 4 | 1,056
gastric carcinoma 4 | 832
head and neck cancer 4 | 270
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
pediatric high grade glioma 4 | 2,712
pilocytic astrocytoma 4 | 3,086
posterior fossa group A ependymoma 4 | 1,511
Alzheimer's disease 3 | 644
Epidermolytic hyperkeratosis 3 | 13
Hypertensive disease 3 | 193
Irritant dermatitis 3 | 9
Keratosis 3 | 34
Schizophrenia 3 | 503
adrenocortical carcinoma 3 | 1,427
adult high grade glioma 3 | 2,148
astrocytoma 3 | 1,493
atypical teratoid/rhabdoid tumor 3 | 1,095
colon cancer 3 | 1,475
interstitial lung disease 3 | 292
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
juvenile dermatomyositis 3 | 1,189
limb girdle muscular dystrophy 2A 3 | 156
oligodendroglioma 3 | 2,849
pituitary cancer 3 | 1,972
primary Sjogren syndrome 3 | 788
spina bifida 3 | 1,064
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 1,563
Amyotrophic Lateral Sclerosis 2 | 432
Animal Mammary Neoplasms 2 | 135
Aortic valve insufficiency 2 | 22
Bullous pemphigoid 2 | 17
Disease Progression 2 | 125
Dry eye syndrome 2 | 14
Fibrosis 2 | 40
Left Ventricular Hypertrophy 2 | 24
Liver Cirrhosis 2 | 101
Liver diseases 2 | 66
Mammary Neoplasms 2 | 410
Mammary Neoplasms, Experimental 2 | 149
Neoplasm Invasiveness 2 | 127
Neoplasm Metastasis 2 | 138
Neurodegenerative disease 2 | 383
Palmoplantar keratosis 2 | 36
Peeling skin syndrome 2 | 16
Pemphigus 2 | 18
Polycystic Ovary Syndrome 2 | 334
Psoriatic arthritis 2 | 85
Skin Neoplasms 2 | 49
Skin disease 2 | 65
Waldenstrons macroglobulinemia 2 | 764
acute quadriplegic myopathy 2 | 1,157
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
chronic lymphosyte leukemia 2 | 232
dermatomyositis 2 | 966
fascioscapulohumeral muscular dystrophy 2 | 100
group 4 medulloblastoma 2 | 1,875
head and neck cancer and chronic obstructive pulmonary disease 2 | 237
mucosa-associated lymphoid tissue lymphoma 2 | 480
nephrosclerosis 2 | 329
periodontitis 2 | 269
primitive neuroectodermal tumor 2 | 3,031
pterygium 2 | 74
sonic hedgehog group medulloblastoma 2 | 1,482
urothelial carcinoma 2 | 318
Cardiomyopathy, Dilated 1 | 47
Erythema multiforme 1 | 15
Idiopathic pulmonary fibrosis 1 | 21

Tissue

Digestive Tract 48 | 18,472
Endocrine System 48 | 18,511
Female tissues 48 | 18,646
Skin and soft tissues 48 | 18,114
Nervous System 47 | 18,560
Urinary Tract 44 | 18,443
Blood and immune system 43 | 17,994
Cardiovascular System 42 | 17,957
Liver and Pancreas 40 | 18,135
Male tissues 35 | 17,968
Respiratory system 32 | 17,483

Target Family

Non-IDG 40 | 11,969
Enzyme 8 | 4,146
Transporter 1 | 473

GO Process

peptide cross-linking 49 | 49
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Late cornified envelope protein 5A LCE5A Tdark Non-IDG 0.50 0.32 0
Protein-glutamine gamma-glutamyltransferase 5 TGM5 Tbio Enzyme -1.90931 75.5 113
Collagen alpha-1(III) chain COL3A1 Tchem Non-IDG -2.54818 328.8 384
Late cornified envelope protein 4A LCE4A Tdark Non-IDG 0.12 0.33 0
Late cornified envelope protein 2A LCE2A Tdark Non-IDG -0.17609 1.29 4
Late cornified envelope protein 3A LCE3A Tdark Non-IDG -0.05754 1.31 0
Late cornified envelope protein 3B LCE3B Tbio Non-IDG -1.13279 16.5 0
Late cornified envelope protein 2C LCE2C Tdark Non-IDG 0.00000 0
Late cornified envelope protein 2D LCE2D Tdark Non-IDG 1.00 0.08 1
Late cornified envelope-like proline-rich protein 1 LELP1 Tdark Non-IDG -0.01424 1.51 12