Development Level

Tbio 24 | 11,445
Tchem 2 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

decreased circulating alkaline... 2 | 46
preweaning lethality, incomple... 2 | 499
abnormal locomotor activation 1 | 16
decreased IgE level 1 | 6
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased circulating triglyce... 1 | 79
decreased lean body mass 1 | 135
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
impaired glucose tolerance 1 | 75
increased circulating calcium ... 1 | 34
increased circulating glucose ... 1 | 24
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
mammalian phenotype 1 | 17
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 17 | 11,493
atypical teratoid / rhabdoid tumor 11 | 5,112
glioblastoma 11 | 5,792
medulloblastoma, large-cell 11 | 6,241
psoriasis 11 | 6,694
Breast cancer 10 | 3,578
ovarian cancer 10 | 8,520
group 3 medulloblastoma 9 | 4,104
osteosarcoma 9 | 7,950
Astrocytoma, Pilocytic 8 | 3,081
adult high grade glioma 8 | 3,801
ependymoma 8 | 4,679
lung cancer 8 | 4,740
non-small cell lung cancer 8 | 2,890
Cleft Palate 7 | 271
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
lung adenocarcinoma 7 | 2,716
Autosomal recessive predisposition 6 | 1,442
Cognitive delay 6 | 608
Dull intelligence 6 | 645
Global developmental delay 6 | 608
Intellectual disability 6 | 1,016
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental and motor retardation 6 | 608
Mental deficiency 6 | 645
Poor school performance 6 | 645
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
invasive ductal carcinoma 6 | 2,951
lung carcinoma 6 | 2,843
malignant mesothelioma 6 | 3,232
pancreatic cancer 6 | 2,398
spina bifida 6 | 1,074
Cancer 5 | 2,499
Cleft Lip 5 | 141
Conductive hearing loss 5 | 123
Craniofacial Abnormalities 5 | 151
Orbital separation excessive 5 | 244
Short stature 5 | 531
astrocytic glioma 5 | 2,597
breast carcinoma 5 | 1,638
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
oligodendroglioma 5 | 2,850
primitive neuroectodermal tumor 5 | 3,035
Abnormally small eyeball 4 | 97
Broad flat nasal bridge 4 | 236
Byzanthine arch palate 4 | 194
Cleft uvula 4 | 27
Decreased projection of midface 4 | 105
Decreased size of eyeball 4 | 97
Epilepsy 4 | 792
Highly variable severity 4 | 157
Holoprosencephaly 4 | 56
Hypotrophic malar bone 4 | 129
Hypotrophic midface 4 | 105
Kidney cancer 4 | 2,613
Malar flattening 4 | 129
Microphthalmos 4 | 100
Midface retrusion 4 | 105
Muscle hypotonia 4 | 571
Nasal bridge wide 4 | 236
Polydactyly 4 | 107
Rheumatoid arthritis 4 | 1,191
Small head 4 | 374
Small midface 4 | 105
Uranostaphyloschisis 4 | 167
Variable expressivity 4 | 157
ductal carcinoma in situ 4 | 1,745
pediatric high grade glioma 4 | 1,064
Absent auditory canals 3 | 23
Absent external auditory canals 3 | 23
Atresia of the external auditory canal 3 | 23
Atretic auditory canal 3 | 23
Blepharoptosis 3 | 231
Congenital Epicanthus 3 | 177
Congenital Heart Defects 3 | 58
Congenital deafness 3 | 185
Congenital heart disease 3 | 93
Deafness 3 | 198
Hearing Loss, Partial 3 | 185
Hypoplasia of the maxilla 3 | 66
Liver cancer 3 | 604
Long face 3 | 71
Maxillary retrognathia 3 | 66
Melanoma 3 | 711
Pick disease 3 | 1,894
RENAL ADYSPLASIA 3 | 25
Renal dysplasia 3 | 28
Retrognathia 3 | 54
Schizophrenia 3 | 1,160
Seizures 3 | 596
Sensorineural Hearing Loss (disorder) 3 | 284
Short philtrum 3 | 53
Ulnar polydactyly of fingers 3 | 47
colon cancer 3 | 1,478
hearing impairment 3 | 199
primary pancreatic ductal adenocarcinoma 3 | 1,109
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819

Tissue

Digestive Tract 25 | 17,369
Endocrine System 24 | 18,159
Female tissues 24 | 17,400
Male tissues 24 | 17,142
Urinary Tract 24 | 16,678
Skin and soft tissues 23 | 17,230
Liver and Pancreas 22 | 16,750
Respiratory system 22 | 16,393
Blood and immune system 21 | 16,909
Nervous System 21 | 16,725
Cardiovascular System 18 | 15,192

Target Family

Transcription Factor 14 | 1,400
Non-IDG 7 | 12,091
Enzyme 6 | 4,145

GO Process

pattern specification process 27 | 27
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-1,3-N-acetylglucosaminyltransferase radical fringe RFNG Tdark Enzyme -0.37913 1.57 92
Ras/Rap GTPase-activating protein SynGAP SYNGAP1 Tbio Enzyme -1.91757 81.2 178
Retinal homeobox protein Rx RAX Tbio Transcription Factor -0.52554 4.68 205
T-box transcription factor TBX1 TBX1 Tbio Transcription Factor -1.99519 95.5 207
Homeobox protein Hox-B1 HOXB1 Tbio Transcription Factor -2.04135 107.7 264
Zinc finger E-box-binding homeobox 1 ZEB1 Tbio Transcription Factor -2.88752 659.2 460
Sclerostin domain-containing protein 1 SOSTDC1 Tbio Non-IDG -2.29355 177.8 109
Beta-1,3-N-acetylglucosaminyltransferase manic fringe MFNG Tbio Enzyme -0.83827 6.67 114
Protein Shroom3 SHROOM3 Tbio Non-IDG -1.57599 36.8 31
LIM/homeobox protein Lhx1 LHX1 Tbio Transcription Factor -1.69625 49.3 365