Development Level

Tbio 62 | 10,625
Tchem 13 | 1,890
Tclin 1 | 602

IMPC Phenotype

preweaning lethality, incomple... 5 | 260
preweaning lethality, complete... 4 | 633
decreased body weight 2 | 174
decreased lean body mass 2 | 195
embryonic lethality prior to t... 2 | 187
enlarged heart 2 | 111
abnormal behavior 1 | 226
abnormal coat-hair pigmentatio... 1 | 54
abnormal facial morphology 1 | 9
cleft palate 1 | 6
cyanosis 1 | 6
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating choleste... 1 | 85
decreased circulating fructosa... 1 | 31
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased eosinophil cell numb... 1 | 41
decreased lumbar vertebrae num... 1 | 62
hydrops fetalis 1 | 22
hyperactivity 1 | 108
impaired glucose tolerance 1 | 52
increased or absent threshold ... 1 | 128
increased prepulse inhibition 1 | 21
limb grasping 1 | 35
shortened QT interval 1 | 4
small superior vagus ganglion 1 | 20

Disease

ovarian cancer 43 | 8,491
lung cancer 35 | 4,473
osteosarcoma 34 | 7,933
psoriasis 34 | 6,685
medulloblastoma, large-cell 31 | 6,234
Cancer 27 | 2,346
invasive ductal carcinoma 24 | 2,950
non-small cell lung cancer 24 | 2,798
atypical teratoid / rhabdoid tumor 23 | 4,369
glioblastoma 23 | 5,572
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,956
Breast cancer 22 | 3,098
Cleft palate 21 | 125
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,988
Carcinoma 20 | 2,147
lung adenocarcinoma 18 | 2,714
pancreatic cancer 18 | 2,300
pilocytic astrocytoma 18 | 3,086
Craniofacial Abnormalities 17 | 147
lung carcinoma 17 | 2,844
malignant mesothelioma 17 | 3,163
ductal carcinoma in situ 16 | 1,745
group 3 medulloblastoma 16 | 2,254
interstitial cystitis 16 | 2,299
cystic fibrosis 15 | 1,670
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,289
pediatric high grade glioma 14 | 2,712
pituitary cancer 13 | 1,972
posterior fossa group A ependymoma 13 | 1,511
primitive neuroectodermal tumor 13 | 3,031
acute quadriplegic myopathy 12 | 1,157
breast carcinoma 12 | 1,614
colon cancer 12 | 1,475
ependymoma 12 | 2,514
Cleft Lip 11 | 91
primary pancreatic ductal adenocarcinoma 11 | 1,271
sonic hedgehog group medulloblastoma 11 | 1,482
oligodendroglioma 10 | 2,849
Pick disease 9 | 1,893
Polydactyly 9 | 93
gastric carcinoma 9 | 832
group 4 medulloblastoma 9 | 1,875
juvenile dermatomyositis 9 | 1,189
posterior fossa group B ependymoma 9 | 1,530
spina bifida 9 | 1,064
tuberculosis 9 | 1,563
ulcerative colitis 9 | 2,087
adrenocortical carcinoma 8 | 1,427
adult high grade glioma 8 | 2,148
astrocytoma 8 | 1,493
Congenital heart disease 7 | 63
Intellectual disability 7 | 573
active ulcerative colitis 7 | 477
cutaneous lupus erythematosus 7 | 1,056
dermatomyositis 7 | 966
fibroadenoma 7 | 557
head and neck cancer 7 | 270
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,795
subependymal giant cell astrocytoma 7 | 2,287
Coloboma 6 | 52
Craniosynostosis 6 | 47
Obesity 6 | 616
Osteoporosis 6 | 259
Stomach Neoplasms 6 | 282
astrocytic glioma 6 | 2,241
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 499
Atopic dermatitis 5 | 944
Eye Abnormalities 5 | 15
Hydrolethalus syndrome 5 | 128
Microphthalmia 5 | 79
Synostosis 5 | 18
Tooth agenesis 5 | 38
active Crohn's disease 5 | 918
primary Sjogren syndrome 5 | 788
Aortic aneurysm 4 | 34
Duchenne muscular dystrophy 4 | 602
Familial thoracic aortic aneurysm and aortic dissection 4 | 13
Kidney disease 4 | 397
Mammary Neoplasms 4 | 410
Neoplasm Invasiveness 4 | 127
Neoplasm Metastasis 4 | 138
Omphalocele 4 | 22
Osteoarthritis 4 | 96
Prostate cancer 4 | 172
Rheumatoid Arthritis 4 | 1,170
Waldenstrons macroglobulinemia 4 | 764
X-linked cerebral adrenoleukodystrophy 4 | 115
acute myeloid leukemia 4 | 785
atypical teratoid/rhabdoid tumor 4 | 1,095
chronic rhinosinusitis 4 | 512
diabetes mellitus 4 | 1,663
nasopharyngeal carcinoma 4 | 1,056
Heart disease 3 | 279
Migraine 3 | 79
Vascular disease 3 | 281
inflammatory breast cancer 3 | 404
medulloblastoma 3 | 1,524
mucosa-associated lymphoid tissue lymphoma 3 | 480
nephrosclerosis 3 | 329
urothelial carcinoma 3 | 318

Tissue

Digestive Tract 76 | 18,472
Endocrine System 76 | 18,511
Female tissues 76 | 18,646
Male tissues 76 | 17,968
Nervous System 76 | 18,560
Respiratory system 76 | 17,483
Skin and soft tissues 76 | 18,114
Urinary Tract 76 | 18,443
Blood and immune system 75 | 17,994
Liver and Pancreas 75 | 18,135
Cardiovascular System 74 | 17,957

Target Family

Non-IDG 32 | 11,969
Transcription Factor 28 | 1,400
Kinase 7 | 634
Enzyme 5 | 4,146
Epigenetic 2 | 242
Ion Channel 1 | 341
TF/Epigenetic 1 | 38

GO Process

palate development 76 | 76
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Extracellular tyrosine-protein kinase PKDCC PKDCC Tbio Kinase -1.14420 14.3 48
TGF-beta receptor type-2 TGFBR2 Tchem Kinase -2.81736 519.3 441
Zinc finger protein SNAI2 SNAI2 Tbio Transcription Factor -3.22534 1564.7 495
Collagen alpha-1(II) chain COL2A1 Tbio Non-IDG -2.86562 689.3 377
Transcription factor 21 TCF21 Tbio Transcription Factor -1.77727 57.8 121
Small ubiquitin-related modifier 1 SUMO1 Tbio Non-IDG -2.69416 474.2 685
Cysteine/serine-rich nuclear protein 1 CSRNP1 Tbio Non-IDG -0.82723 7.95 82
Zinc finger protein basonuclin-2 BNC2 Tbio Transcription Factor -1.43318 28.0 57
Growth/differentiation factor 11 GDF11 Tbio Non-IDG -1.94486 91.4 192
Sphingosine-1-phosphate lyase 1 SGPL1 Tchem Enzyme -2.02204 102.8 120