Development Level

Tbio 81 | 10,625
Tchem 30 | 1,890
Tdark 19 | 7,003
Tclin 3 | 602

Collection

Eligible Ion Channel Proteins 1 | 117

IMPC Term

preweaning lethality, complete... 7 | 633
abnormal lens morphology 5 | 73
abnormal behavior 4 | 226
abnormal retina morphology 3 | 100
decreased bone mineral content 3 | 157
embryonic lethality prior to o... 3 | 148
abnormal bone mineralization 2 | 55
cataract 2 | 26
decreased bone mineral density 2 | 126
decreased circulating calcium ... 2 | 33
decreased circulating choleste... 2 | 85
decreased circulating triglyce... 2 | 83
decreased mean corpuscular vol... 2 | 50
embryonic lethality prior to t... 2 | 187
hypoactivity 2 | 89
increased bone mineral content 2 | 92
increased fasted circulating g... 2 | 68
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 93
persistence of hyaloid vascula... 2 | 22
abnormal QRS complex 1 | 25
abnormal bone structure 1 | 131
abnormal coat/hair pigmentatio... 1 | 54
abnormal cranium morphology 1 | 32
abnormal digit morphology 1 | 13
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal gait 1 | 51
abnormal heart left ventricle ... 1 | 20
abnormal iris morphology 1 | 12
abnormal jejunum morphology 1 | 1
abnormal locomotor activation 1 | 26
abnormal lung morphology 1 | 15
abnormal placement of pupils 1 | 4
abnormal respiratory quotient 1 | 9
abnormal response to new envir... 1 | 8
abnormal retinal blood vessel ... 1 | 18
abnormal retinal vasculature m... 1 | 15
abnormal skin appearance 1 | 8
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal snout morphology 1 | 18
abnormal testis morphology 1 | 30
absent vibrissae 1 | 14
anophthalmia 1 | 20
convulsive seizures 1 | 11
craniofacial phenotype 1 | 9
decreased NK cell number 1 | 16
decreased blood urea nitrogen ... 1 | 31
decreased body weight 1 | 174
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating alkaline... 1 | 41
decreased circulating bilirubi... 1 | 14
decreased circulating insulin ... 1 | 75
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased hemoglobin content 1 | 53
decreased lean body mass 1 | 195
decreased neutrophil cell numb... 1 | 37
decreased prepulse inhibition 1 | 52
decreased red blood cell distr... 1 | 11
decreased threshold for audito... 1 | 32
decreased total body fat amoun... 1 | 186
enlarged heart 1 | 111
enlarged heart atrium 1 | 2
enlarged lymph nodes 1 | 27
hydrops fetalis 1 | 22
impaired righting response 1 | 19
increased body length 1 | 20
increased circulating alkaline... 1 | 119
increased circulating amylase ... 1 | 13
increased circulating free fat... 1 | 17
increased circulating fructosa... 1 | 11
increased circulating iron lev... 1 | 25
increased circulating magnesiu... 1 | 10
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 24
increased erythrocyte cell num... 1 | 26
increased heart weight 1 | 37
increased hematocrit 1 | 36
increased mean corpuscular vol... 1 | 91
increased red blood cell distr... 1 | 21
increased spleen weight 1 | 3
increased startle reflex 1 | 38
microcephaly 1 | 3
microphthalmia 1 | 15
narrow eye opening 1 | 15
polycystic kidney 1 | 9
preweaning lethality, incomple... 1 | 260
small kidney 1 | 10
stereotypic behavior 1 | 3
tremors 1 | 34
trunk curl 1 | 15

Disease

ovarian cancer 64 | 8,484
osteosarcoma 62 | 7,933
psoriasis 59 | 6,685
lung cancer 45 | 4,466
medulloblastoma, large-cell 44 | 6,234
pancreatic ductal adenocarcinoma liver metastasis 37 | 1,795
glioblastoma 34 | 5,572
non-small cell lung cancer 32 | 2,798
atypical teratoid / rhabdoid tumor 30 | 4,369
interstitial cystitis 29 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,289
malignant mesothelioma 28 | 3,162
Cancer 27 | 2,346
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,956
tuberculosis 27 | 1,557
invasive ductal carcinoma 25 | 2,950
lung carcinoma 23 | 2,844
pancreatic cancer 23 | 2,300
primitive neuroectodermal tumor 23 | 3,031
pilocytic astrocytoma 21 | 3,086
ulcerative colitis 19 | 2,087
astrocytic glioma 18 | 2,241
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,988
lung adenocarcinoma 18 | 2,713
Pick disease 17 | 1,893
cystic fibrosis 17 | 1,665
oligodendroglioma 17 | 2,849
subependymal giant cell astrocytoma 17 | 2,287
adrenocortical carcinoma 16 | 1,427
diabetes mellitus 16 | 1,663
ductal carcinoma in situ 16 | 1,745
posterior fossa group B ependymoma 16 | 1,530
Breast cancer 15 | 3,094
ependymoma 15 | 2,514
pediatric high grade glioma 15 | 2,712
primary pancreatic ductal adenocarcinoma 15 | 1,271
adult high grade glioma 14 | 2,148
medulloblastoma 14 | 1,524
esophageal adenocarcinoma 13 | 737
gastric carcinoma 13 | 832
breast carcinoma 12 | 1,614
group 4 medulloblastoma 12 | 1,875
nasopharyngeal carcinoma 12 | 1,056
Atopic dermatitis 11 | 944
Multiple myeloma 11 | 1,327
colon cancer 11 | 1,475
cutaneous lupus erythematosus 11 | 1,056
group 3 medulloblastoma 11 | 2,254
pituitary cancer 11 | 1,972
posterior fossa group A ependymoma 11 | 1,511
Hypertension 10 | 287
Prostatic Neoplasms 10 | 471
active Crohn's disease 10 | 918
acute quadriplegic myopathy 10 | 1,157
Kidney disease 9 | 396
acute myeloid leukemia 9 | 780
non primary Sjogren syndrome sicca 9 | 840
Atherosclerosis 8 | 275
Mammary Neoplasms 8 | 410
astrocytoma 8 | 1,493
head and neck cancer and chronic obstructive pulmonary disease 8 | 237
sonic hedgehog group medulloblastoma 8 | 1,482
Alzheimer's disease 7 | 644
Chronic granulomatous disease 7 | 13
Liver disease 7 | 219
Polycystic Ovary Syndrome 7 | 332
aldosterone-producing adenoma 7 | 664
atypical teratoid/rhabdoid tumor 7 | 1,095
juvenile dermatomyositis 7 | 1,189
Adverse reaction to drug 6 | 54
Carcinoma 6 | 2,147
Cerebrovascular disease 6 | 231
Congenital adrenal hyperplasia 6 | 74
Duchenne muscular dystrophy 6 | 602
Endometriosis 6 | 535
Epilepsy 6 | 346
Liver carcinoma 6 | 217
Neurodegenerative disease 6 | 383
Obesity 6 | 616
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 499
nephrosclerosis 6 | 329
primary Sjogren syndrome 6 | 789
spina bifida 6 | 1,064
Acute kidney injury 5 | 65
Cardiovascular system disease 5 | 194
Colorectal Neoplasms 5 | 217
Contact Dermatitis 5 | 80
Drug-Induced Liver Injury 5 | 118
Glaucoma 5 | 134
IGA Glomerulonephritis 5 | 454
Kidney Failure, Chronic 5 | 45
Lung Neoplasms 5 | 171
Malaria 5 | 140
Neoplastic Cell Transformation 5 | 81
Rheumatoid Arthritis 5 | 1,160
Schizophrenia 5 | 501
pancreatic carcinoma 5 | 567
Waldenstrons macroglobulinemia 4 | 765
dermatomyositis 4 | 933
non diabetic and post-ischemic heart failure 4 | 200

Tissue

Blood and immune system 130 | 17,995
Digestive Tract 130 | 18,473
Endocrine System 130 | 18,512
Liver and Pancreas 130 | 18,136
Nervous System 130 | 18,561
Cardiovascular System 129 | 17,958
Female tissues 129 | 18,647
Male tissues 129 | 17,969
Urinary Tract 129 | 18,444
Respiratory system 128 | 17,484
Skin and soft tissues 128 | 18,115

Target Family

Enzyme 79 | 4,146
Non-IDG 51 | 11,971
Ion Channel 3 | 341

GO Process

oxidation-reduction process 133 | 133
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thioredoxin-like protein AAED1 AAED1 Tdark Non-IDG 0.43 0.35 30
Protein SCO2 homolog, mitochondrial SCO2 Tbio Non-IDG -2.16453 144.3 98
Cytochrome b-245 light chain CYBA Tbio Non-IDG -2.56294 358.8 154
Glutamate dehydrogenase 2, mitochondrial GLUD2 Tbio Enzyme -1.13407 13.6 143
Cytochrome b561 CYB561 Tbio Non-IDG -1.41910 20.4 45
FAD-dependent oxidoreductase domain-containing protein 2 FOXRED2 Tdark Enzyme -0.17609 2.34 58
Lysyl oxidase homolog 1 LOXL1 Tbio Enzyme -2.51621 344.5 145
Alpha-synuclein SNCA Tchem Non-IDG -3.59982 3997.3 1484
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ACADM Tbio Enzyme -2.58670 387.0 269
Dihydrofolate reductase DHFR Tclin Enzyme -2.97865 960.4 158