Development Level

Tbio 84 | 11,445
Tchem 15 | 1,598
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 12 | 979
enlarged heart 7 | 210
embryonic lethality prior to t... 6 | 278
decreased vertical activity 4 | 208
embryonic lethality prior to o... 4 | 239
abnormal embryo size 3 | 220
preweaning lethality, incomple... 3 | 499
abnormal embryo turning 2 | 31
abnormal heart morphology 2 | 162
abnormal kidney morphology 2 | 65
abnormal neural tube closure 2 | 46
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased circulating alanine ... 2 | 47
decreased circulating aspartat... 2 | 34
decreased circulating choleste... 2 | 93
increased circulating alkaline... 2 | 122
increased startle reflex 2 | 112
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal body wall morphology 1 | 9
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo development 1 | 7
abnormal iris morphology 1 | 13
abnormal lung morphology 1 | 26
abnormal neural tube morpholog... 1 | 12
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
abnormal urinary bladder morph... 1 | 11
absent testes 1 | 6
cataract 1 | 92
cleft palate 1 | 8
decreased circulating HDL chol... 1 | 68
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating total pr... 1 | 49
decreased hematocrit 1 | 46
decreased lactate dehydrogenas... 1 | 16
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
hydrometra 1 | 53
improved glucose tolerance 1 | 79
increased circulating glucose ... 1 | 24
increased grip strength 1 | 41
increased heart rate variabili... 1 | 7
increased mean corpuscular hem... 1 | 36
increased monocyte cell number 1 | 63
pale yolk sac 1 | 25
pallor 1 | 34
polycystic kidney 1 | 15
short tibia 1 | 97
small spleen 1 | 19
small testis 1 | 58

Disease

Carcinoma 75 | 11,493
ovarian cancer 60 | 8,520
psoriasis 52 | 6,694
lung cancer 49 | 4,740
Cancer 48 | 2,499
osteosarcoma 48 | 7,950
atypical teratoid / rhabdoid tumor 41 | 5,112
glioblastoma 41 | 5,792
medulloblastoma, large-cell 39 | 6,241
ependymoma 36 | 4,679
Breast cancer 31 | 3,578
invasive ductal carcinoma 29 | 2,951
adult high grade glioma 28 | 3,801
non-small cell lung cancer 28 | 2,890
group 3 medulloblastoma 26 | 4,104
Astrocytoma, Pilocytic 25 | 3,081
lung adenocarcinoma 25 | 2,716
pancreatic cancer 24 | 2,398
malignant mesothelioma 23 | 3,232
ulcerative colitis 23 | 1,819
acute quadriplegic myopathy 22 | 1,158
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
Breast Neoplasms 20 | 445
Kidney cancer 20 | 2,613
breast carcinoma 20 | 1,638
pituitary cancer 20 | 1,972
primitive neuroectodermal tumor 20 | 3,035
colon cancer 19 | 1,478
diabetes mellitus 19 | 1,728
oligodendroglioma 19 | 2,850
Mammary Neoplasms 18 | 425
Osteoporosis 18 | 363
group 4 medulloblastoma 18 | 1,855
interstitial cystitis 18 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
adrenocortical carcinoma 16 | 1,428
ductal carcinoma in situ 16 | 1,745
tuberculosis 16 | 2,010
Multiple myeloma 15 | 1,332
astrocytic glioma 15 | 2,597
cystic fibrosis 15 | 1,696
juvenile dermatomyositis 15 | 1,187
lung carcinoma 15 | 2,843
subependymal giant cell astrocytoma 15 | 2,287
astrocytoma 14 | 1,146
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
Short stature 13 | 531
dermatomyositis 13 | 966
nasopharyngeal carcinoma 13 | 1,058
primary pancreatic ductal adenocarcinoma 13 | 1,109
Autosomal recessive predisposition 12 | 1,442
Cleft Palate 12 | 271
Down syndrome 12 | 499
Duchenne muscular dystrophy 11 | 601
Intellectual disability 11 | 1,016
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 510
pediatric high grade glioma 11 | 1,064
Atopic dermatitis 10 | 952
Cognitive delay 10 | 608
Global developmental delay 10 | 608
Mental and motor retardation 10 | 608
Obesity 10 | 678
Waldenstrons macroglobulinemia 10 | 765
active ulcerative colitis 10 | 764
gastric carcinoma 10 | 807
spina bifida 10 | 1,074
Ankylosis 9 | 28
Craniosynostosis 9 | 74
Epilepsy 9 | 792
Lung Neoplasms 9 | 232
Orbital separation excessive 9 | 244
Pick disease 9 | 1,894
Seizures 9 | 596
Becker muscular dystrophy 8 | 191
Cleft Lip 8 | 141
Hypotrophic malar bone 8 | 129
Kidney disease 8 | 430
Malar flattening 8 | 129
Neoplasm Metastasis 8 | 168
Rheumatoid arthritis 8 | 1,191
Stomach Neoplasms 8 | 300
aldosterone-producing adenoma 8 | 665
cutaneous lupus erythematosus 8 | 1,057
esophageal adenocarcinoma 8 | 737
Acquired scoliosis 7 | 281
Amyotrophic lateral sclerosis 7 | 451
Concave bridge of nose 7 | 195
Curvature of spine 7 | 282
Depressed nasal bridge 7 | 195
Depressed nasal root/bridge 7 | 195
Disease Models, Animal 7 | 155
Liver Cirrhosis, Experimental 7 | 769
Muscle hypotonia 7 | 571
Osteoarthritis 7 | 184
active Crohn's disease 7 | 922
medulloblastoma 7 | 720
periodontitis 7 | 293
primary Sjogren syndrome 7 | 735
sarcoidosis 7 | 370

Tissue

Endocrine System 100 | 18,159
Female tissues 100 | 17,400
Digestive Tract 98 | 17,369
Liver and Pancreas 98 | 16,750
Male tissues 98 | 17,142
Nervous System 98 | 16,725
Respiratory system 98 | 16,393
Skin and soft tissues 98 | 17,230
Blood and immune system 96 | 16,909
Urinary Tract 96 | 16,678
Cardiovascular System 92 | 15,192

Target Family

Non-IDG 61 | 12,091
Transcription Factor 18 | 1,400
Enzyme 17 | 4,145
GPCR 2 | 408
Kinase 2 | 634
Epigenetic 1 | 242

GO Process

osteoblast differentiation 101 | 101
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Integrin alpha-11 ITGA11 Tbio Non-IDG -1.13736 14.3 76
Myocilin MYOC Tbio Non-IDG -2.65916 482.8 169
Staphylococcal nuclease domain-containing protein 1 SND1 Tbio Epigenetic -2.35812 225.9 175
Transmembrane glycoprotein NMB GPNMB Tbio Non-IDG -2.05817 130.8 293
Growth/differentiation factor 2 GDF2 Tbio Non-IDG -2.16825 176.4 239
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
Isoleucine--tRNA ligase, cytoplasmic IARS Tchem Enzyme -3.11190 1198.0 95
Retinol dehydrogenase 14 RDH14 Tbio Enzyme -0.13566 1.51 40
Heterogeneous nuclear ribonucleoprotein U HNRNPU Tbio Non-IDG -2.33813 207.8 169
Collagen alpha-1(VI) chain COL6A1 Tbio Non-IDG -2.03348 104.7 204