Development Level

Tbio 11 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal sensory capabilities-... 1 | 8
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
embryonic lethality prior to t... 1 | 278
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
vertebral fusion 1 | 23

Disease

Carcinoma 12 | 11,493
glioblastoma 7 | 5,792
ovarian cancer 7 | 8,520
atypical teratoid / rhabdoid tumor 6 | 5,112
adult high grade glioma 5 | 3,801
ependymoma 5 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
medulloblastoma, large-cell 5 | 6,241
osteosarcoma 5 | 7,950
Astrocytoma, Pilocytic 4 | 3,081
Breast cancer 4 | 3,578
adrenocortical carcinoma 4 | 1,428
colon cancer 4 | 1,478
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung cancer 4 | 4,740
oligodendroglioma 4 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
psoriasis 4 | 6,694
Albinism with hemorrhagic diathesis and pigmented reticuloendothelial cells 3 | 7
Epilepsy 3 | 792
Hermanski-Pudlak Syndrome 3 | 8
Hermansky-Pudlak syndrome 3 | 42
Oculocutaneous albinism 3 | 29
Pick disease 3 | 1,894
Platelet storage pool deficiency 3 | 21
Pulmonary Fibrosis 3 | 106
Schizophrenia 3 | 1,160
Seizures 3 | 596
astrocytic glioma 3 | 2,597
breast carcinoma 3 | 1,638
fibroadenoma 3 | 559
invasive ductal carcinoma 3 | 2,951
lung carcinoma 3 | 2,843
non primary Sjogren syndrome sicca 3 | 891
subependymal giant cell astrocytoma 3 | 2,287
Atopic dermatitis 2 | 952
Bipolar Disorder 2 | 666
Cancer 2 | 2,499
Congenital nystagmus 2 | 26
Crohn's disease 2 | 321
Depressive disorder 2 | 409
Diarrhea 2 | 253
Hermansky-Pudlak Syndrome 1 2 | 6
Irritable bowel syndrome 2 | 60
astrocytoma 2 | 1,146
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
primitive neuroectodermal tumor 2 | 3,035
Achromasia 1 | 11
Acrokeratosis verruciformis 1 | 1
Bipolar I disorder 1 | 23
Carcinoma, Non-Small-Cell Lung 1 | 107
Celiac disease 1 | 116
Ciliopathy 1 | 71
Dermatitis herpetiformis 1 | 12
Diabetes Mellitus, Experimental 1 | 108
Epidermolytic hyperkeratosis 1 | 14
Fatty Liver 1 | 70
Fatty liver disease 1 | 103
Gastritis 1 | 47
Gastrointestinal Stromal Tumors 1 | 48
Glioma 1 | 74
Glomangiomatosis 1 | 4
Glucose Intolerance 1 | 19
Hair shaft abnormalities 1 | 30
Hyperkeratosis 1 | 50
Hyperkyphosis 1 | 111
Hyperpigmented macules 1 | 42
Immunoglobulin alpha deficiency 1 | 11
Impaired glucose tolerance 1 | 28
Insulin Resistance 1 | 72
Keratosis follicularis 1 | 3
Kyphosis deformity of spine 1 | 114
Lordosis 1 | 54
MAJOR AFFECTIVE DISORDER 1 1 | 2
MAJOR AFFECTIVE DISORDER 7 1 | 1
Myocardial stunning 1 | 8
Non-alcoholic Fatty Liver Disease 1 | 42
Organic writer's cramp 1 | 10
Orofaciodigital syndrome 1 | 21
Palmar pit 1 | 4
Palmoplantar keratosis 1 | 74
Pernicious anemia 1 | 9
Phaeochromocytoma 1 | 20
Pheochromocytoma 1 | 24
Plantar pits 1 | 4
Poor speech 1 | 37
Problems speaking 1 | 37
Ridged nails 1 | 14
Ventricular Dysfunction, Left 1 | 22
X- linked recessive 1 | 110
hair abnormalities (non-specific) 1 | 30

Tissue

Blood and immune system 12 | 16,909
Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678
Cardiovascular System 11 | 15,192

Target Family

Non-IDG 10 | 12,091
Transcription Factor 1 | 1,400
Transporter 1 | 473

GO Process

organelle organization 12 | 12
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.87498 737.3 295
Kinesin-like protein KIF25 KIF25 Tbio Non-IDG -0.75019 5.59 191
Chromosome-associated kinesin KIF4A KIF4A Tbio Non-IDG -1.91717 78.0 157
Hermansky-Pudlak syndrome 3 protein HPS3 Tbio Non-IDG -1.24807 18.4 141
Kinesin heavy chain isoform 5C KIF5C Tbio Non-IDG -1.43450 25.5 119
Kinesin-like protein KIF3A KIF3A Tbio Non-IDG -2.06068 113.6 153
Hermansky-Pudlak syndrome 6 protein HPS6 Tbio Non-IDG -1.07016 12.2 101
Torsin-1A TOR1A Tbio Non-IDG -3.10052 1230.7 179
Hermansky-Pudlak syndrome 5 protein HPS5 Tbio Non-IDG -1.16348 15.2 81