Development Level

Tbio 8 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

embryonic lethality prior to t... 3 | 278
preweaning lethality, complete... 3 | 979
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
cataract 1 | 92
corneal opacity 1 | 32
decreased lean body mass 1 | 135
decreased threshold for audito... 1 | 26
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
fused cornea and lens 1 | 5
impaired pupillary reflex 1 | 26
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased total body fat amoun... 1 | 134
iris synechia 1 | 3
male infertility 1 | 123
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33

Disease

Cancer 8 | 2,499
osteosarcoma 6 | 7,950
atypical teratoid / rhabdoid tumor 5 | 5,112
glioblastoma 5 | 5,792
malignant mesothelioma 5 | 3,232
medulloblastoma, large-cell 5 | 6,241
ovarian cancer 5 | 8,520
Breast cancer 4 | 3,578
Carcinoma 4 | 11,493
Cleft Palate 4 | 271
Renal agenesis 4 | 29
breast carcinoma 4 | 1,638
ependymoma 4 | 4,679
invasive ductal carcinoma 4 | 2,951
Astrocytoma, Pilocytic 3 | 3,081
Cleft Lip 3 | 141
Craniofacial Abnormalities 3 | 151
Cryptorchidism 3 | 296
Downward slant of palpebral fissure 3 | 158
Sensorineural Hearing Loss (disorder) 3 | 284
adrenocortical carcinoma 3 | 1,428
lung carcinoma 3 | 2,843
psoriasis 3 | 6,694
Abnormality of body height 2 | 13
Abnormality of the voice 2 | 46
Absence of pubertal development 2 | 17
Absence of secondary sex characteristics 2 | 22
Acrocephalosyndactylia 2 | 17
Alzheimer's disease 2 | 658
Anosmia 2 | 22
Anxiety 2 | 136
Anxiety disease 2 | 113
Bilateral fifth finger clinodactyly 2 | 110
Bipolar Disorder 2 | 666
Breast Neoplasms 2 | 445
Broad hallux 2 | 29
Byzanthine arch palate 2 | 194
CHARGE syndrome 2 | 26
Cardiovascular Abnormalities 2 | 31
Choanal Atresia 2 | 42
Congenital hypoplasia of breast 2 | 25
Craniosynostosis 2 | 74
Curvature of little finger 2 | 110
Decreased bone mineral density Z score 2 | 31
Decreased fertility 2 | 33
Decreased size of teeth 2 | 62
Decreased testosterone in males 2 | 28
Decreased width of tooth 2 | 59
Delayed Puberty 2 | 97
Delayed bone age 2 | 136
Depressive disorder 2 | 409
Endometrial Neoplasms 2 | 55
Erectile dysfunction 2 | 32
Eunuchoid habitus 2 | 14
Female hypogonadism syndrome 2 | 25
Generalized osteopenia 2 | 99
Glioma 2 | 74
Gynecomastia 2 | 64
Holoprosencephaly 2 | 56
Hypodontia 2 | 81
Hypogonadism, Isolated Hypogonadotropic 2 | 71
Hypogonadotropic hypogonadism 2 | 89
Hypoplastic ovary 2 | 30
Hypospadias 2 | 53
Increased female libido 2 | 13
Infantile uterus 2 | 23
Kallmann Syndrome 2 (disorder) 2 | 18
Klinefelter's syndrome 2 | 56
Major Depressive Disorder 2 | 301
Mammary Neoplasms 2 | 425
Microdontia (disorder) 2 | 59
Non-obstructive azoospermia 2 | 21
Osteopenia 2 | 99
Osteoporosis 2 | 363
Parkinson's disease 2 | 392
Primary physiologic amenorrhea 2 | 55
Respiratory Insufficiency 2 | 132
Respiratory function loss 2 | 121
Schizophrenia 2 | 1,160
Secondary physiologic amenorrhea 2 | 32
Small testicle 2 | 75
Sparse body hair 2 | 32
Telecanthus 2 | 62
Testicular hypogonadism 2 | 21
Unipolar Depression 2 | 250
Uranostaphyloschisis 2 | 167
Wide spaced nipples 2 | 46
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
cystic fibrosis 2 | 1,696
ductal carcinoma in situ 2 | 1,745
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
tuberculosis 2 | 2,010

Tissue

Blood and immune system 10 | 16,909
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Male tissues 10 | 17,142
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678
Liver and Pancreas 8 | 16,750
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Cardiovascular System 7 | 15,192

Target Family

Non-IDG 6 | 12,091
Transcription Factor 3 | 1,400
Kinase 1 | 634

GO Process

organ induction 10 | 10
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Fibroblast growth factor receptor 1 FGFR1 Tclin Kinase -3.13063 1294.7 1785
Homeobox protein Hox-C11 HOXC11 Tbio Transcription Factor -1.24766 17.3 174
Homeobox protein Hox-A11 HOXA11 Tbio Transcription Factor -1.96653 87.2 270
Protein sprouty homolog 1 SPRY1 Tbio Non-IDG -2.19105 141.2 190
Fibroblast growth factor receptor substrate 2 FRS2 Tbio Non-IDG -2.37203 224.0 344
Fibroblast growth factor 10 FGF10 Tbio Non-IDG -2.55166 363.0 320
Glial cell line-derived neurotrophic factor GDNF Tbio Non-IDG -3.34041 2403.4 393
Homeobox protein SIX1 SIX1 Tbio Transcription Factor -2.64041 433.7 111
Fibroblast growth factor 8 FGF8 Tbio Non-IDG -2.73368 532.0 299
Fibroblast growth factor 1 FGF1 Tchem Non-IDG -3.21050 1645.9 514