Development Level

Tbio 3 | 11,445
Tclin 3 | 613
Tchem 2 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

abnormal eating behavior 1 | 1
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal forced expiratory flo... 1 | 1
abnormal whole-body plethysmog... 1 | 4
altered righting response 1 | 1
decreased body temperature 1 | 2
decreased body weight 1 | 161
decreased startle reflex 1 | 75
decreased tidal volume 1 | 1
increased blood urea nitrogen ... 1 | 48
increased circulating iron lev... 1 | 30
increased grip strength 1 | 41
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
pale yolk sac 1 | 25
pallor 1 | 34
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 8 | 11,493
Breast cancer 6 | 3,578
lung cancer 6 | 4,740
medulloblastoma, large-cell 6 | 6,241
Cancer 5 | 2,499
Kidney cancer 4 | 2,613
group 3 medulloblastoma 4 | 4,104
osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
psoriasis 4 | 6,694
Bipolar Disorder 3 | 666
Breast Neoplasms 3 | 445
Mammary Neoplasms 3 | 425
Multiple myeloma 3 | 1,332
Schizophrenia 3 | 1,160
Ventricular Septal Defects 3 | 119
atypical teratoid / rhabdoid tumor 3 | 5,112
colon cancer 3 | 1,478
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
oligodendroglioma 3 | 2,850
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
ATRIOVENTRICULAR CANAL DEFECT 2 | 17
Adenocarcinoma 2 | 122
Angle class 2 malocclusion 2 | 57
Angle class 3 malocclusion 2 | 57
Asthma 2 | 385
Astrocytoma, Pilocytic 2 | 3,081
Atrial Septal Defects 2 | 85
Autistic Disorder 2 | 364
Blepharoptosis 2 | 231
Brachydactyly 2 | 156
Byzanthine arch palate 2 | 194
Class III malocclusion 2 | 78
Cleft Palate 2 | 271
Congenital heart disease 2 | 93
Craniofacial Abnormalities 2 | 151
Cryptorchidism 2 | 296
Decreased projection of midface 2 | 105
Depressive disorder 2 | 409
Diabetes Mellitus, Experimental 2 | 108
Down syndrome 2 | 499
Downward slant of palpebral fissure 2 | 158
Endocardial Cushion Defects 2 | 17
Exophthalmos 2 | 112
Feeding difficulties in infancy 2 | 175
Fetal Alcohol Spectrum Disorders 2 | 13
Fetal alcohol syndrome 2 | 22
Fever 2 | 138
High forehead 2 | 102
Hypertension 2 | 396
Hypertensive disease 2 | 292
Hypertrophy of lower jaw 2 | 78
Hypoplastic mandible condyle 2 | 275
Hypotrophic midface 2 | 105
Immune system cancer 2 | 140
Increased size of mandible 2 | 78
Intellectual disability 2 | 1,016
Leukemia, Myeloid, Acute 2 | 105
Liver Cirrhosis 2 | 181
Low set ears 2 | 181
Low-set, posteriorly rotated ears 2 | 110
Lymphoid leukemia 2 | 160
Male infertility 2 | 206
Malocclusion 2 | 57
Mandibular hyperplasia 2 | 78
Mandibular hypoplasia 2 | 275
Melanocytic nevus 2 | 43
Micrognathism 2 | 275
Midface retrusion 2 | 105
Mild Mental Retardation 2 | 70
Noncancerous mole 2 | 28
Orbital separation excessive 2 | 244
Pick disease 2 | 1,894
Prominent eyes 2 | 96
Prominent globes 2 | 96
Protruding eyes 2 | 96
Right atrial isomerism 2 | 29
Short stature 2 | 531
Skin hyperelastic 2 | 32
Small midface 2 | 105
Somatic mutation 2 | 61
Strabismus 2 | 270
Tall forehead 2 | 102
Uranostaphyloschisis 2 | 167
Ventricular Remodeling 2 | 5
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
malignant mesothelioma 2 | 3,232
mandibular excess (physical finding) 2 | 78
pituitary cancer 2 | 1,972

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Non-IDG 3 | 12,091
Enzyme 2 | 4,145
Kinase 2 | 634
GPCR 1 | 408
Transcription Factor 1 | 1,400

GO Process

organ growth 9 | 9
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mothers against decapentaplegic homolog 2 SMAD2 Tbio Transcription Factor -3.26675 1515.7 1396
Tyrosine-protein phosphatase non-receptor type 11 PTPN11 Tchem Enzyme -3.11032 1400.0 1077
Fibroblast growth factor receptor 2 FGFR2 Tclin Kinase -3.08664 1210.6 948
Delta-like protein 1 DLL1 Tbio Non-IDG -3.09375 1190.2 344
Alpha-1A adrenergic receptor ADRA1A Tclin GPCR -2.18682 155.5 236
Apoptosis regulator Bcl-2 BCL2 Tclin Non-IDG -2.20455 130.6 2273
Activin receptor type-2B ACVR2B Tchem Kinase -2.14321 122.9 303
Neuroligin-4, X-linked NLGN4X Tbio Enzyme -1.77739 57.8 135
Putative gap junction epsilon-1 protein GJE1 Tdark Non-IDG -0.53712 3.69 16