Development Level

Tbio 6 | 11,445
Tchem 4 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

enlarged lymph nodes 1 | 37
preweaning lethality, incomple... 1 | 499
small adrenal glands 1 | 16
small superior vagus ganglion 1 | 74

Disease

Carcinoma 7 | 11,493
ovarian cancer 7 | 8,520
psoriasis 5 | 6,694
Autosomal recessive predisposition 4 | 1,442
Gangliosidosis 4 | 20
Glycoproteinosis 4 | 12
Muscle hypotonia 4 | 571
glioblastoma 4 | 5,792
lung cancer 4 | 4,740
medulloblastoma, large-cell 4 | 6,241
osteosarcoma 4 | 7,950
Coarse facial features 3 | 108
Dull intelligence 3 | 645
Epilepsy 3 | 792
Hyperreflexia 3 | 209
Intellectual disability 3 | 1,016
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Poor school performance 3 | 645
Seizures 3 | 596
Thickened facial skin with coarse facial features 3 | 108
alpha-mannosidosis 3 | 8
malignant mesothelioma 3 | 3,232
Astrocytoma, Pilocytic 2 | 3,081
Big calvaria 2 | 147
Blind Vision 2 | 111
Blindness, Legal 2 | 110
Cardiomegaly 2 | 116
Cerebellar Ataxia 2 | 304
Cherry red spot of the macula 2 | 7
Cognitive delay 2 | 608
Congenital pectus carinatum 2 | 52
Dysarthria 2 | 192
Frontal bossing 2 | 157
Global developmental delay 2 | 608
Hepatomegaly 2 | 285
Hernia, Inguinal 2 | 89
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Kidney cancer 2 | 2,613
Macroglossia 2 | 65
Mental and motor retardation 2 | 608
Multiple myeloma 2 | 1,332
Muscle Weakness 2 | 170
Neurogenic Muscular Atrophy 2 | 139
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
Nystagmus 2 | 317
Pfaundler-Hurler Syndrome 2 | 12
Pick disease 2 | 1,894
Rheumatoid arthritis 2 | 1,191
Sandhoff disease 2 | 3
Sensorineural Hearing Loss (disorder) 2 | 284
Skeletal muscle atrophy 2 | 139
Speech Disorders 2 | 58
Splenomegaly 2 | 190
Tay-Sachs disease 2 | 6
Vacuolated lymphocytes 2 | 8
astrocytoma 2 | 1,146
atypical teratoid / rhabdoid tumor 2 | 5,112
beta-mannosidosis 2 | 9
diabetes mellitus 2 | 1,728
esophageal adenocarcinoma 2 | 737
group 4 medulloblastoma 2 | 1,855
inclusion-cell disease 2 | 16
muscle degeneration 2 | 139
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Abnormal urinary amino-acid findings 1 | 38
Aminoaciduria 1 | 38
Angiokeratoma 1 | 9
Ascites 1 | 22
Cerebellar Dysmetria 1 | 56
Cholera 1 | 34
Decreased projection of midface 1 | 105
Decreased visual acuity, progressive 1 | 36
Epicondylitis 1 | 22
Full lower lip 1 | 64
Gas gangrene 1 | 17
Hydrops Fetalis 1 | 21
Hyperactive behavior 1 | 91
Hyperkeratosis 1 | 50
Hypertrichosis 1 | 46
Hypotrophic midface 1 | 105
Increased susceptibility to bacterial infections 1 | 42
Midface retrusion 1 | 105
Myoclonus 1 | 74
Paralysed 1 | 42
Pre-Eclampsia 1 | 68
Progressive visual loss 1 | 36
Prominent lower lip 1 | 64
Prone to bacterial infection 1 | 42
Recurrent bacterial infection 1 | 42
Recurrent infections 1 | 48
Short thorax 1 | 21
Small midface 1 | 105
Tularemia 1 | 23
Vitiligo 1 | 73
intermittent abdominal pain 1 | 9

Tissue

Female tissues 11 | 17,400
Skin and soft tissues 11 | 17,230
Blood and immune system 10 | 16,909
Cardiovascular System 10 | 15,192
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Urinary Tract 10 | 16,678
Respiratory system 9 | 16,393

Target Family

Enzyme 10 | 4,145
Non-IDG 1 | 12,091

GO Process

oligosaccharide catabolic proc... 11 | 11
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Di-N-acetylchitobiase CTBS Tbio Enzyme -2.28326 196.4 113
Sialidase-3 NEU3 Tbio Enzyme -2.02704 118.2 35
Lysosomal alpha-mannosidase MAN2B1 Tchem Enzyme -2.18158 152.9 35
Beta-mannosidase MANBA Tchem Enzyme -2.02551 103.8 50
Sialidase-1 NEU1 Tbio Enzyme -2.07548 116.0 278
Alpha-mannosidase 2C1 MAN2C1 Tbio Enzyme -2.29349 188.5 81
Epididymis-specific alpha-mannosidase MAN2B2 Tdark Enzyme -0.56418 3.49 38
Sialidase-4 NEU4 Tchem Enzyme -1.39624 25.1 115
Sialidase-2 NEU2 Tbio Enzyme -2.12721 129.5 166
Ganglioside GM2 activator GM2A Tbio Non-IDG -2.03952 111.9 325