Development Level

Tbio 6 | 11,445

IMPC Phenotype

abnormal behavior 1 | 298
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal spleen morphology 1 | 55
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased lean body mass 1 | 135
decreased lumbar vertebrae num... 1 | 2
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged spleen 1 | 41
hydrometra 1 | 53
hyperactivity 1 | 148

Disease

Carcinoma 6 | 11,493
adult high grade glioma 4 | 3,801
atypical teratoid / rhabdoid tumor 4 | 5,112
medulloblastoma, large-cell 4 | 6,241
psoriasis 4 | 6,694
Intellectual disability 3 | 1,016
Osteoporosis 3 | 363
Sensorineural hearing loss 3 | 106
Anxiety 2 | 136
Anxiety disease 2 | 113
Astrocytoma, Pilocytic 2 | 3,081
Autistic Disorder 2 | 364
Blepharoptosis 2 | 231
Congenital deafness 2 | 185
Deafness 2 | 198
Deglutition Disorders 2 | 132
Delayed Puberty 2 | 97
Depressive disorder 2 | 409
Dull intelligence 2 | 645
Hearing Loss, Partial 2 | 185
Hydronephrosis 2 | 89
Hypothyroidism 2 | 122
Kidney cancer 2 | 2,613
Liver cancer 2 | 604
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Nonsyndromic deafness 2 | 142
Nystagmus 2 | 317
Optic Atrophy 2 | 242
Poor school performance 2 | 645
Psychotic Disorders 2 | 151
Schizophrenia 2 | 1,160
Testicular hypogonadism 2 | 21
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
hearing impairment 2 | 199
osteosarcoma 2 | 7,950
ovarian cancer 2 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primitive neuroectodermal tumor 2 | 3,035
Abnormality of body height 1 | 13
Absence of pubertal development 1 | 17
Absence of secondary sex characteristics 1 | 22
Anemia, Megaloblastic 1 | 16
Anophthalmos 1 | 13
Aplasia/Hypoplasia of the earlobes 1 | 10
Atrophy of testis 1 | 14
Atypical lymphocyte observed 1 | 10
Autistic behavior 1 | 20
Bifid scrotum 1 | 16
CHARGE syndrome 1 | 26
Central Diabetes Insipidus 1 | 5
Cervical cancer 1 | 24
Choanal Atresia 1 | 42
Chronic diarrhea 1 | 29
Coloboma 1 | 51
Congenital ichthyosiform erythroderma 1 | 28
Congenital sensorineural hearing loss 1 | 12
Decreased fertility 1 | 33
Decreased testosterone in males 1 | 28
Desquamation of skin soon after birth 1 | 10
Diabetes insipidus 1 | 18
Diffusely thickened skin 1 | 20
Edema 1 | 81
Erectile dysfunction 1 | 32
Erythrokeratodermia variabilis 1 | 10
Esophageal atresia with or without tracheoesophageal fistula 1 | 21
Eunuchoid habitus 1 | 14
Exfoliative dermatitis 1 | 24
Facial asymmetry 1 | 32
Female hypogonadism syndrome 1 | 25
Fundus coloboma 1 | 18
Gynecomastia 1 | 64
Hypocalcemia 1 | 32
Idiopathic hypogonadotropic hypogonadism 1 | 21
Increased female libido 1 | 13
Infantile uterus 1 | 23
Kallmann Syndrome 2 (disorder) 1 | 18
Labial hypoplasia 1 | 3
Lichen nitidus 1 | 3
Narrow face 1 | 54
Non-obstructive azoospermia 1 | 21
Obsessive compulsive behavior 1 | 25
Oculodentodigital dysplasia 1 | 14
Omenn syndrome 1 | 13
Ovarian mucinous cystadenocarcinoma 1 | 2
Overfolded helix 1 | 24
Pachyderma 1 | 20
Polydipsia 1 | 15
Postnatal growth retardation 1 | 57
Primary gonadal insufficiency 1 | 9
Primary physiologic amenorrhea 1 | 55
Progressive cerebellar ataxia 1 | 13
Ritscher-Schinzel syndrome 1 | 11
Sparse body hair 1 | 32
Square face 1 | 3
Thin face 1 | 54
Wide spaced nipples 1 | 46
esophageal atresia/tracheoesophageal fistula 1 | 22

Tissue

Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Skin and soft tissues 6 | 17,230
Blood and immune system 5 | 16,909
Urinary Tract 5 | 16,678
Nervous System 4 | 16,725
Cardiovascular System 3 | 15,192
Respiratory system 3 | 16,393

Target Family

Non-IDG 3 | 12,091
Enzyme 1 | 4,145
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

GO Process

olfactory behavior 6 | 6
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Wolframin WFS1 Tbio Non-IDG -2.40006 260.2 118
E3 ubiquitin-protein ligase UBR3 UBR3 Tbio Enzyme -0.89502 8.28 22
Chromodomain-helicase-DNA-binding protein 7 CHD7 Tbio Epigenetic -2.91077 788.8 102
LIM homeobox transcription factor 1-alpha LMX1A Tbio Transcription Factor -1.82498 66.0 175
Gap junction beta-4 protein GJB4 Tbio Non-IDG -1.60100 40.2 125
SH3 and multiple ankyrin repeat domains protein 1 SHANK1 Tbio Non-IDG -1.58468 39.2 170