Development Level

Tbio 41 | 11,445
Tchem 8 | 1,598
Tclin 7 | 613

IMPC Phenotype

preweaning lethality, complete... 14 | 979
enlarged heart 4 | 210
increased total body fat amoun... 4 | 134
increased circulating HDL chol... 3 | 80
increased circulating choleste... 3 | 66
preweaning lethality, incomple... 3 | 499
abnormal bone mineralization 2 | 38
abnormal embryo development 2 | 7
abnormal embryo size 2 | 220
abnormal facial morphology 2 | 17
abnormal lens morphology 2 | 81
abnormal optic disc morphology 2 | 10
abnormal retinal blood vessel ... 2 | 26
abnormal retinal vasculature m... 2 | 27
cataract 2 | 92
corneal opacity 2 | 32
decreased body weight 2 | 161
decreased lean body mass 2 | 135
decreased startle reflex 2 | 75
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
impaired glucose tolerance 2 | 75
increased monocyte cell number 2 | 63
increased startle reflex 2 | 112
mammalian phenotype 2 | 17
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal eyelid fusion 1 | 3
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal pericardium morpholog... 1 | 26
abnormal response to new envir... 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal startle reflex 1 | 15
abnormal tooth morphology 1 | 24
abnormal vitreous body morphol... 1 | 10
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
cleft palate 1 | 8
cyanosis 1 | 7
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 28
decreased erythrocyte cell num... 1 | 62
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
edema 1 | 59
embryonic growth retardation 1 | 106
fused cornea and lens 1 | 5
hemorrhage 1 | 23
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased bone mineral density 1 | 72
increased fasted circulating g... 1 | 76
increased heart rate variabili... 1 | 7
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased vertical activity 1 | 24
iris synechia 1 | 3
irregularly shaped pupil 1 | 7
limb grasping 1 | 41
narrow eye opening 1 | 12
pale yolk sac 1 | 25
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
small testis 1 | 58

Disease

Carcinoma 34 | 11,493
medulloblastoma, large-cell 30 | 6,241
psoriasis 30 | 6,694
Cancer 29 | 2,499
osteosarcoma 27 | 7,950
lung cancer 26 | 4,740
ovarian cancer 24 | 8,520
atypical teratoid / rhabdoid tumor 23 | 5,112
glioblastoma 23 | 5,792
ependymoma 19 | 4,679
malignant mesothelioma 17 | 3,232
Breast cancer 15 | 3,578
invasive ductal carcinoma 15 | 2,951
non-small cell lung cancer 15 | 2,890
pancreatic cancer 15 | 2,398
Astrocytoma, Pilocytic 14 | 3,081
Cleft Palate 13 | 271
Kidney cancer 13 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
group 3 medulloblastoma 12 | 4,104
interstitial cystitis 12 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
oligodendroglioma 12 | 2,850
Cleft Lip 11 | 141
Craniofacial Abnormalities 11 | 151
astrocytic glioma 11 | 2,597
colon cancer 11 | 1,478
group 4 medulloblastoma 11 | 1,855
Orbital separation excessive 10 | 244
Short stature 10 | 531
Tooth agenesis 10 | 44
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
primitive neuroectodermal tumor 10 | 3,035
Epilepsy 9 | 792
Hypoplastic mandible condyle 9 | 275
Mandibular hypoplasia 9 | 275
Micrognathism 9 | 275
Schizophrenia 9 | 1,160
breast carcinoma 9 | 1,638
ductal carcinoma in situ 9 | 1,745
Breast Neoplasms 8 | 445
Cognitive delay 8 | 608
Decreased projection of maxilla 8 | 66
Decreased size of teeth 8 | 62
Decreased width of tooth 8 | 59
Deficiency of upper jaw bones 8 | 66
Global developmental delay 8 | 608
Hypodontia 8 | 81
Hypoplasia of the maxilla 8 | 66
Hypotrophic malar bone 8 | 129
Hypotrophic maxilla 8 | 66
Malar flattening 8 | 129
Maxillary retrognathia 8 | 66
Mental and motor retardation 8 | 608
Microdontia (disorder) 8 | 59
Osteoporosis 8 | 363
Retrusion of upper jaw bones 8 | 66
adult high grade glioma 8 | 3,801
cutaneous lupus erythematosus 8 | 1,057
lung adenocarcinoma 8 | 2,716
tuberculosis 8 | 2,010
Autosomal recessive predisposition 7 | 1,442
Decreased projection of midface 7 | 105
Frontal bossing 7 | 157
Hypotrophic midface 7 | 105
Intellectual disability 7 | 1,016
Mammary Neoplasms 7 | 425
Melanoma 7 | 711
Midface retrusion 7 | 105
Pick disease 7 | 1,894
Polydactyly 7 | 107
Small midface 7 | 105
Stomach Neoplasms 7 | 300
Syndactyly 7 | 88
Tooth Abnormalities 7 | 69
Vascular disease 7 | 319
lung carcinoma 7 | 2,843
spina bifida 7 | 1,074
ulcerative colitis 7 | 1,819
Alzheimer's disease 6 | 658
Concave bridge of nose 6 | 195
Deafness 6 | 198
Depressed nasal bridge 6 | 195
Depressed nasal root/bridge 6 | 195
Dull intelligence 6 | 645
Hearing Loss, Partial 6 | 185
Liver cancer 6 | 604
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Multiple myeloma 6 | 1,332
Poor school performance 6 | 645
Prostatic Neoplasms 6 | 495
Rheumatoid arthritis 6 | 1,191
Seizures 6 | 596
Skin cancer 6 | 469
cystic fibrosis 6 | 1,696
pediatric high grade glioma 6 | 1,064
pituitary cancer 6 | 1,972
subependymal giant cell astrocytoma 6 | 2,287

Tissue

Endocrine System 55 | 18,159
Digestive Tract 51 | 17,369
Male tissues 51 | 17,142
Female tissues 50 | 17,400
Blood and immune system 49 | 16,909
Liver and Pancreas 48 | 16,750
Skin and soft tissues 48 | 17,230
Urinary Tract 48 | 16,678
Nervous System 47 | 16,725
Respiratory system 45 | 16,393
Cardiovascular System 42 | 15,192

Target Family

Non-IDG 29 | 12,091
Transcription Factor 18 | 1,400
Kinase 3 | 634
Epigenetic 2 | 242
Ion Channel 2 | 344
Enzyme 1 | 4,145
GPCR 1 | 408

GO Process

odontogenesis of dentin-contai... 56 | 56
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium channel protein type 10 subunit alpha SCN10A Tclin Ion Channel -3.17690 1469.3 126
Protein Wnt-6 WNT6 Tbio Non-IDG -1.65830 46.6 186
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
LIM/homeobox protein Lhx8 LHX8 Tbio Transcription Factor -1.58436 40.6 163
Homeobox protein MSX-1 MSX1 Tbio Transcription Factor -2.59245 390.1 298
T-box transcription factor TBX1 TBX1 Tbio Transcription Factor -1.99519 95.5 207
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.65728 4647.9 684
ADM ADM Tbio Non-IDG -3.27504 1889.0 381
Ankyrin repeat domain-containing protein 11 ANKRD11 Tbio Non-IDG -2.55588 339.7 93
Forkhead box protein C1 FOXC1 Tbio Transcription Factor -2.28586 201.8 314