Development Level

Tbio 21 | 11,445

IMPC Phenotype

increased startle reflex 2 | 112
preweaning lethality, complete... 2 | 979
abnormal body wall morphology 1 | 9
abnormal embryo size 1 | 220
abnormal kidney morphology 1 | 65
abnormal skin morphology 1 | 50
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged spleen 1 | 41
increased leukocyte cell numbe... 1 | 47
polycystic kidney 1 | 15
prenatal lethality prior to he... 1 | 87
protruding tongue 1 | 3

Disease

ovarian cancer 15 | 8,520
psoriasis 10 | 6,694
lung cancer 7 | 4,740
osteosarcoma 7 | 7,950
Carcinoma 6 | 11,493
atypical teratoid / rhabdoid tumor 6 | 5,112
ependymoma 6 | 4,679
astrocytic glioma 5 | 2,597
group 3 medulloblastoma 5 | 4,104
pancreatic cancer 5 | 2,398
Breast cancer 4 | 3,578
Multiple myeloma 4 | 1,332
Neurodegenerative disease 4 | 414
Pick disease 4 | 1,894
dermatomyositis 4 | 966
glioblastoma 4 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
malignant mesothelioma 4 | 3,232
medulloblastoma, large-cell 4 | 6,241
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
spina bifida 4 | 1,074
Atopic dermatitis 3 | 952
Autosomal recessive predisposition 3 | 1,442
Dysarthria 3 | 192
Muscle Spasticity 3 | 195
adult high grade glioma 3 | 3,801
ductal carcinoma in situ 3 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung adenocarcinoma 3 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primary pancreatic ductal adenocarcinoma 3 | 1,109
progressive supranuclear palsy 3 | 676
tuberculosis 3 | 2,010
Absent reflex 2 | 92
Absent tendon reflex 2 | 92
Adult onset 2 | 82
Alzheimer's disease 2 | 658
Astrocytoma, Pilocytic 2 | 3,081
Babinski Reflex 2 | 100
Bipolar Disorder 2 | 666
Cancer 2 | 2,499
Cerebellar Ataxia 2 | 304
Cerebellar Dysmetria 2 | 56
Chorea 2 | 29
Choreatic disease 2 | 52
DOID:2627 2 | 94
Deglutition Disorders 2 | 132
Dementia 2 | 175
Gait Ataxia 2 | 51
Hyperreflexia 2 | 209
Intellectual disability 2 | 1,016
Kidney cancer 2 | 2,613
Liver cancer 2 | 604
Poor speech 2 | 37
Problems speaking 2 | 37
Reflex, Deep Tendon, Absent 2 | 92
acute quadriplegic myopathy 2 | 1,158
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
esophageal adenocarcinoma 2 | 737
hepatocellular carcinoma 2 | 547
interstitial lung disease 2 | 298
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
juvenile dermatomyositis 2 | 1,187
lingual-facial-buccal dyskinesia 2 | 13
lung carcinoma 2 | 2,843
non primary Sjogren syndrome sicca 2 | 891
pancreatic carcinoma 2 | 562
pituitary cancer 2 | 1,972
primary Sjogren syndrome 2 | 735
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Acute cystitis 1 | 35
Apathy 1 | 16
Aphasia 1 | 26
Apraxias 1 | 27
Ataxia, Appendicular 1 | 25
Autosomal dominant Robinow syndrome 1 1 | 15
Centronuclear myopathy 1 | 27
DOID:9917 1 | 31
Danon disease 1 | 8
Dysphonia 1 | 7
Galloway-Mowat syndrome 1 | 15
Hyperkyphosis 1 | 111
Irritation - emotion 1 | 68
Kaposi's sarcoma 1 | 22
Kyphosis deformity of spine 1 | 114
Muscle Cramp 1 | 55
Muscle Rigidity 1 | 49
Muscle atrophy, proximal 1 | 11
Olivopontocerebellar Atrophies 1 | 6
Pain 1 | 103
Postnatal microcephaly 1 | 24
Rapidly progressive 1 | 27
Rapidly progressive disorder 1 | 27
Restlessness 1 | 14
Slowed saccades 1 | 12
Spinocerebellar ataxia type 7 1 | 13

Tissue

Blood and immune system 21 | 16,909
Digestive Tract 21 | 17,369
Endocrine System 21 | 18,159
Female tissues 21 | 17,400
Male tissues 21 | 17,142
Respiratory system 21 | 16,393
Cardiovascular System 20 | 15,192
Liver and Pancreas 20 | 16,750
Nervous System 20 | 16,725
Skin and soft tissues 20 | 17,230
Urinary Tract 20 | 16,678

Target Family

Non-IDG 21 | 12,091

GO Process

nucleus organization 21 | 21
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nuclear mitotic apparatus protein 1 NUMA1 Tbio Non-IDG -2.76544 575.8 235
Charged multivesicular body protein 7 CHMP7 Tbio Non-IDG -0.61033 3.61 30
Charged multivesicular body protein 1a CHMP1A Tbio Non-IDG -1.15571 14.9 161
WD repeat-containing protein 73 WDR73 Tbio Non-IDG -1.34700 19.4 70
Golgi membrane protein 1 GOLM1 Tbio Non-IDG -2.01519 123.3 449
Charged multivesicular body protein 2b CHMP2B Tbio Non-IDG -1.71624 54.4 193
Charged multivesicular body protein 1b CHMP1B Tbio Non-IDG -0.73722 3.70 71
Charged multivesicular body protein 4a CHMP4A Tbio Non-IDG -1.17768 16.3 29
Charged multivesicular body protein 4c CHMP4C Tbio Non-IDG -0.86389 7.74 42
Ataxin-7 ATXN7 Tbio Non-IDG -2.33556 232.9 120