Development Level

Tbio 2 | 11,651

Disease

Arthralgia 2 | 90
Atrophic condition of skin 2 | 25
Autosomal recessive predisposition 2 | 1,442
Basal cell carcinoma 2 | 54
Cancer 2 | 2,499
Carcinoma 2 | 11,493
Cataract 2 | 297
Cerebellar Ataxia 2 | 304
Cockayne syndrome 2 | 60
Conjunctival telangiectasis 2 | 14
Cryptorchidism 2 | 296
Defective DNA repair after ultraviolet radiation damage 2 | 7
Dental abnormalities 2 | 60
Developmental regression 2 | 95
Dry skin 2 | 75
Dull intelligence 2 | 645
Electroencephalogram abnormal 2 | 101
Erythema 2 | 58
Failure to gain weight 2 | 365
Fanconi anemia 2 | 56
Fatigue 2 | 182
Fever 2 | 138
Flushing 2 | 60
Freckles 2 | 33
Hyperkeratosis 2 | 50
Hyperpigmented macules 2 | 42
Hypogonadism 2 | 173
Impaired cognition 2 | 96
Intellectual disability 2 | 1,016
Keratitis 2 | 62
Lens Opacities 2 | 231
Loss of developmental milestones 2 | 95
Low intelligence 2 | 645
Melanoma 2 | 711
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Mental deterioration in childhood 2 | 95
Mental impairment 2 | 95
Micronuclei, Chromosome-Defective 2 | 25
Muscle Spasticity 2 | 195
Neurodevelopmental regression 2 | 95
Optic Atrophy 2 | 242
Papilloma 2 | 44
Pediatric failure to thrive 2 | 365
Photosensitivity of skin 2 | 51
Poikiloderma 2 | 14
Poor school performance 2 | 645
Progressive mental retardation 2 | 37
Psychomotor regression 2 | 95
Psychomotor regression beginning in infancy 2 | 95
Psychomotor regression in infants 2 | 95
Psychomotor regression, progressive 2 | 95
Sensorineural Hearing Loss (disorder) 2 | 284
Small head 2 | 374
Strabismus 2 | 270
Telangiectasia of the skin 2 | 39
Thin skin 2 | 47
Tooth Abnormalities 2 | 69
Xeroderma pigmentosum 2 | 43
Xerosis 2 | 75
hypopigmented skin patch 2 | 59
osteosarcoma 2 | 7,950
Arsenic Poisoning 1 | 62
Ascites 1 | 22
Basal cell nevi 1 | 23
Bone marrow hypocellularity 1 | 20
Cachexia 1 | 50
Carcinoma, Basal Cell 1 | 28
Conduct disorder 1 | 33
Congenital deafness 1 | 185
Conjunctivitis 1 | 53
Conjunctivitis, recurrent 1 | 37
Decreased platelet count 1 | 111
Defective enamel matrix 1 | 35
Dental Enamel Hypoplasia 1 | 43
Dysplasia of tooth enamel 1 | 35
Enophthalmos 1 | 75
Entropion 1 | 22
Esophageal atresia 1 | 43
Intestinal Neoplasms 1 | 12
Irregular hyperpigmentation 1 | 33
Leukopenia 1 | 72
Mental deterioration 1 | 32
Neoplasm Metastasis 1 | 168
Neoplasms, Germ Cell and Embryonal 1 | 15
Peripheral Neuropathy 1 | 134
Photodysphoria 1 | 121
Photophobia 1 | 121
Poor coordination 1 | 11
Skin benign neoplasm 1 | 6
Spider Veins 1 | 17
Sunken eyes 1 | 63
Telangiectasis 1 | 36
Testicular Neoplasms 1 | 6
Thin dental enamel 1 | 35
Thrombocytopenia 1 | 197
Tracheoesophageal Fistula 1 | 36
Xeroderma pigmentosum group B 1 | 20
Xeroderma pigmentosum group D 1 | 33
hearing impairment 1 | 199

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Enzyme 1 | 4,145
Non-IDG 1 | 12,091

GO Process

nucleotide-excision repair inv... 2 | 2
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA repair protein complementing XP-A cells XPA Tbio Non-IDG -2.87504 739.6 379
DNA repair endonuclease XPF ERCC4 Tbio Enzyme -1.91482 69.2 286