Development Level

Tbio 31 | 10,625
Tchem 5 | 1,890
Tclin 2 | 602

IMPC Phenotype

preweaning lethality, complete... 5 | 633
embryonic lethality prior to o... 4 | 148
embryonic lethality prior to t... 2 | 187
abnormal embryo size 1 | 112
abnormal embryo turning 1 | 15
abnormal pharyngeal arch morph... 1 | 2
abnormal retina morphology 1 | 100
abnormal retinal inner nuclear... 1 | 5
decreased grip strength 1 | 123
decreased total retina thickne... 1 | 20
embryonic growth retardation 1 | 28
increased circulating HDL chol... 1 | 63
increased circulating potassiu... 1 | 31
increased heart weight 1 | 37
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
polydactyly 1 | 22
prenatal lethality prior to he... 1 | 64
preweaning lethality, incomple... 1 | 260

Disease

ovarian cancer 27 | 8,491
osteosarcoma 19 | 7,933
lung cancer 17 | 4,473
Xeroderma pigmentosum 14 | 41
Cancer 13 | 2,346
Cockayne syndrome 13 | 54
malignant mesothelioma 13 | 3,163
medulloblastoma, large-cell 11 | 6,234
psoriasis 11 | 6,685
group 3 medulloblastoma 10 | 2,254
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,289
Photosensitive trichothiodystrophy 9 | 24
glioblastoma 9 | 5,572
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,988
primitive neuroectodermal tumor 8 | 3,031
non-small cell lung cancer 7 | 2,798
Breast cancer 6 | 3,098
Peripheral Neuropathy 6 | 303
astrocytoma 6 | 1,493
atypical teratoid / rhabdoid tumor 6 | 4,369
atypical teratoid/rhabdoid tumor 6 | 1,095
nasopharyngeal carcinoma 6 | 1,056
acute myeloid leukemia 5 | 785
ependymoma 5 | 2,514
oligodendroglioma 5 | 2,849
pediatric high grade glioma 5 | 2,712
Carcinoma 4 | 2,147
Fanconi's anemia 4 | 50
Waldenstrons macroglobulinemia 4 | 764
Xeroderma pigmentosum-Cockayne syndrome complex 4 | 4
diabetes mellitus 4 | 1,663
pituitary cancer 4 | 1,972
Arsenic Poisoning 3 | 59
CAMFAK syndrome 3 | 4
COFS syndrome 3 | 4
Cerebrooculofacioskeletal Syndrome 1 3 | 4
Colorectal Neoplasms 3 | 217
Intellectual disability 3 | 573
Pena Shokeir syndrome Type 2 3 | 4
Pick disease 3 | 1,893
Progeria 3 | 22
Prostatic Neoplasms 3 | 471
Stevens-Johnson syndrome 3 | 91
Stomach Neoplasms 3 | 282
Trichothiodystrophy 1, photosensitive 3 | 4
Trichothiodystrophy Syndromes 3 | 5
astrocytic glioma 3 | 2,241
hepatocellular carcinoma 3 | 550
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
lung adenocarcinoma 3 | 2,714
pancreatic cancer 3 | 2,300
progressive supranuclear palsy 3 | 674
Adenocarcinoma 2 | 115
Adenocarcinoma of lung (disorder) 2 | 48
Alzheimer's disease 2 | 644
Baller-Gerold syndrome 2 | 14
Bladder Neoplasm 2 | 109
Cataract 2 | 104
Cerebro-oculo-facio-skeletal syndrome 2 | 3
Cerebrovascular disease 2 | 231
Chromosome Aberrations 2 | 15
Colonic Neoplasms 2 | 126
Dermatologic disorders 2 | 65
IGA Glomerulonephritis 2 | 454
Lung Neoplasms 2 | 171
Lynch syndrome 2 | 35
Malignant tumor of ovary 2 | 25
Melanoma 2 | 261
Micronuclei, Chromosome-Defective 2 | 20
Multiple myeloma 2 | 1,327
Myofibrillar myopathy 1 2 | 6
Myofibrillar myopathy 3 2 | 5
Neoplasm Metastasis 2 | 138
Neoplasms, Germ Cell and Embryonal 2 | 13
Neurodegenerative disease 2 | 383
Obesity 2 | 616
Pick's disease 2 | 14
Rothmund-Thomson syndrome 2 | 22
Skin Neoplasms 2 | 49
Skin benign neoplasm 2 | 5
Testicular Neoplasms 2 | 5
acute quadriplegic myopathy 2 | 1,157
adrenocortical carcinoma 2 | 1,427
adult high grade glioma 2 | 2,148
breast carcinoma 2 | 1,614
chronic lymphocytic leukemia 2 | 244
cystic fibrosis and chronic rhinosinusitis 2 | 213
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
gastric cancer 2 | 436
invasive ductal carcinoma 2 | 2,950
juvenile dermatomyositis 2 | 1,189
non primary Sjogren syndrome sicca 2 | 840
pancreatic carcinoma 2 | 567
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
posterior fossa group B ependymoma 2 | 1,530
primary pancreatic ductal adenocarcinoma 2 | 1,271
sonic hedgehog group medulloblastoma 2 | 1,482
tuberculosis and treatment for 6 months 2 | 686
Meningeal Leukemia 1 | 7

Tissue

Blood and immune system 38 | 17,994
Cardiovascular System 38 | 17,957
Digestive Tract 38 | 18,472
Endocrine System 38 | 18,511
Female tissues 38 | 18,646
Liver and Pancreas 38 | 18,135
Male tissues 38 | 17,968
Nervous System 38 | 18,560
Respiratory system 38 | 17,483
Skin and soft tissues 38 | 18,114
Urinary Tract 38 | 18,443

Target Family

Non-IDG 24 | 11,969
Enzyme 14 | 4,146

GO Process

nucleotide-excision repair, DN... 38 | 38
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
General transcription factor IIH subunit 3 GTF2H3 Tbio Non-IDG -0.87291 6.02 65
General transcription factor IIH subunit 2 GTF2H2 Tbio Non-IDG -1.31733 6.84 120
DNA repair protein complementing XP-G cells ERCC5 Tchem Enzyme -2.05009 296.8 215
General transcription factor IIH subunit 1 GTF2H1 Tbio Non-IDG -1.64263 41.9 218
DNA excision repair protein ERCC-1 ERCC1 Tbio Non-IDG -3.01167 969.9 606
DNA damage-binding protein 2 DDB2 Tbio Non-IDG -2.05065 116.6 146
General transcription factor IIH subunit 5 GTF2H5 Tbio Non-IDG -1.62240 36.4 42
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.10500 124.2 150
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG -1.62947 56.7 150
N-glycosylase/DNA lyase OGG1 Tbio Enzyme -3.24506 1747.3 234