Development Level

Tbio 18 | 11,651
Tchem 3 | 1,388
Tclin 2 | 612

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to o... 4 | 239
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal pharyngeal arch morph... 1 | 8
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 13 | 11,493
group 3 medulloblastoma 12 | 4,104
malignant mesothelioma 12 | 3,232
ovarian cancer 12 | 8,520
lung cancer 11 | 4,740
osteosarcoma 11 | 7,950
medulloblastoma, large-cell 8 | 6,241
non-small cell lung cancer 8 | 2,890
primitive neuroectodermal tumor 8 | 3,035
Cancer 7 | 2,499
atypical teratoid / rhabdoid tumor 7 | 5,112
glioblastoma 7 | 5,792
psoriasis 7 | 6,694
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
Kidney cancer 5 | 2,613
Breast cancer 4 | 3,578
Hypoplastic mandible condyle 4 | 275
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Short stature 4 | 531
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
nasopharyngeal carcinoma 4 | 1,058
Alzheimer's disease 3 | 658
Colorectal Neoplasms 3 | 243
Waldenstrons macroglobulinemia 3 | 765
Xeroderma pigmentosum 3 | 43
acute myeloid leukemia 3 | 783
adrenocortical carcinoma 3 | 1,428
adult high grade glioma 3 | 3,801
astrocytoma 3 | 1,146
diabetes mellitus 3 | 1,728
ependymoma 3 | 4,679
oligodendroglioma 3 | 2,850
progressive supranuclear palsy 3 | 676
Acute lymphoid leukemia 2 | 25
Acute myeloid leukemia, disease 2 | 30
Acute promyelocytic leukemia, FAB M3 2 | 11
Adenocarcinoma of pancreas 2 | 14
Anemia 2 | 365
Ataxia telangiectasia 2 | 34
Attention deficit hyperactivity disorder 2 | 278
Autosomal recessive predisposition 2 | 1,442
Bilateral fifth finger clinodactyly 2 | 110
Blepharophimosis 2 | 70
Broad flat nasal bridge 2 | 236
Broad forehead 2 | 59
Chronic Lymphocytic Leukemia 2 | 262
Cognitive delay 2 | 608
Colonic Neoplasms 2 | 142
Congenital Epicanthus 2 | 177
Cryptorchidism 2 | 296
Curvature of little finger 2 | 110
DNA ligase IV deficiency 2 | 7
Deafness 2 | 198
Dull intelligence 2 | 645
Erythema 2 | 58
Familial adenomatous polyposis 2 | 32
Global developmental delay 2 | 608
Hepatomegaly 2 | 285
Hyperkyphosis 2 | 111
Intellectual disability 2 | 1,016
Kyphosis deformity of spine 2 | 114
Low intelligence 2 | 645
Low-set, posteriorly rotated ears 2 | 110
Lymphomatous meningitis 2 | 3
Lynch syndrome 2 | 35
Malignant tumor of ovary 2 | 25
Meningeal Leukemia 2 | 7
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Metastatic Breast Carcinoma 2 | 21
Micronuclei, Chromosome-Defective 2 | 25
Multiple myeloma 2 | 1,332
Myofibrillar myopathy 1 2 | 6
Myofibrillar myopathy 3 2 | 5
Narrow face 2 | 54
Nasal bridge wide 2 | 236
Neurodegenerative disease 2 | 414
Photosensitivity of skin 2 | 51
Pick disease 2 | 1,894
Pick's disease 2 | 15
Poor school performance 2 | 645
Prominent ear 2 | 56
Protruding ears 2 | 56
Rheumatoid arthritis 2 | 1,191
Seckel syndrome 2 | 34
Sensorineural Hearing Loss (disorder) 2 | 284
Small head 2 | 374
Submucous cleft of hard palate 2 | 11
Thin face 2 | 54
astrocytic glioma 2 | 2,597
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,109

Tissue

Blood and immune system 23 | 16,909
Cardiovascular System 23 | 15,192
Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Skin and soft tissues 23 | 17,230
Urinary Tract 23 | 16,678

Target Family

Non-IDG 14 | 12,091
Enzyme 9 | 4,145

GO Process

nucleotide-excision repair, DN... 23 | 23
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA polymerase delta catalytic subunit POLD1 Tclin Enzyme -2.06760 110.4 225
DNA polymerase delta subunit 2 POLD2 Tbio Enzyme -0.95222 8.52 115
Replication protein A 70 kDa DNA-binding subunit RPA1 Tchem Non-IDG -2.48277 297.9 350
Replication factor C subunit 4 RFC4 Tbio Non-IDG -1.17661 13.7 195
Replication factor C subunit 5 RFC5 Tbio Non-IDG -1.06074 11.3 79
Proliferating cell nuclear antigen PCNA Tchem Non-IDG -1.13711 11.3 1721
Replication protein A 32 kDa subunit RPA2 Tbio Non-IDG -1.79461 61.4 510
DNA polymerase epsilon catalytic subunit A POLE Tclin Enzyme -2.22644 169.3 112
DNA ligase 3 LIG3 Tbio Enzyme -2.75144 531.1 239
DNA polymerase delta subunit 3 POLD3 Tbio Enzyme -1.31704 20.0 144