Development Level

Tbio 21 | 11,445
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
decreased KLRG1+ CD4 alpha bet... 1 | 5
decreased total retina thickne... 1 | 17
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased anti-nuclear antigen... 1 | 19
increased circulating potassiu... 1 | 29
preweaning lethality, incomple... 1 | 499

Disease

ovarian cancer 16 | 8,520
Cockayne syndrome 14 | 60
Carcinoma 12 | 11,493
Xeroderma pigmentosum 11 | 43
lung cancer 10 | 4,740
osteosarcoma 10 | 7,950
Photosensitive trichothiodystrophy 9 | 30
Cancer 8 | 2,499
Cryptorchidism 6 | 296
Hypogonadism 6 | 173
Melanoma 6 | 711
medulloblastoma, large-cell 6 | 6,241
Arthralgia 5 | 90
Atrophic condition of skin 5 | 25
Autosomal recessive predisposition 5 | 1,442
Basal cell carcinoma 5 | 54
Cataract 5 | 297
Conjunctival telangiectasis 5 | 14
Dental abnormalities 5 | 60
Developmental regression 5 | 95
Dry skin 5 | 75
Electroencephalogram abnormal 5 | 101
Erythema 5 | 58
Failure to gain weight 5 | 365
Fatigue 5 | 182
Fever 5 | 138
Flushing 5 | 60
Freckles 5 | 33
Hyperkeratosis 5 | 50
Hyperpigmented macules 5 | 42
Impaired cognition 5 | 96
Intellectual disability 5 | 1,016
Keratitis 5 | 62
Lens Opacities 5 | 231
Loss of developmental milestones 5 | 95
Mental deterioration in childhood 5 | 95
Mental impairment 5 | 95
Neurodevelopmental regression 5 | 95
Optic Atrophy 5 | 242
Papilloma 5 | 44
Pediatric failure to thrive 5 | 365
Photosensitivity of skin 5 | 51
Poikiloderma 5 | 14
Progressive mental retardation 5 | 37
Psychomotor regression 5 | 95
Psychomotor regression beginning in infancy 5 | 95
Psychomotor regression in infants 5 | 95
Psychomotor regression, progressive 5 | 95
Sensorineural Hearing Loss (disorder) 5 | 284
Strabismus 5 | 270
Telangiectasia of the skin 5 | 39
Thin skin 5 | 47
Tooth Abnormalities 5 | 69
Xerosis 5 | 75
atypical teratoid / rhabdoid tumor 5 | 5,112
hypopigmented skin patch 5 | 59
Basal cell nevi 4 | 23
Breast cancer 4 | 3,578
Conjunctivitis 4 | 53
Conjunctivitis, recurrent 4 | 37
Defective DNA repair after ultraviolet radiation damage 4 | 7
Dull intelligence 4 | 645
Ectropion 4 | 38
Entropion 4 | 22
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Photodysphoria 4 | 121
Photophobia 4 | 121
Poor school performance 4 | 645
Spider Veins 4 | 17
Squamous cell carcinoma of skin 4 | 11
Telangiectasis 4 | 36
Xeroderma pigmentosum group B 4 | 20
Xeroderma pigmentosum group D 4 | 33
acute myeloid leukemia 4 | 783
ependymoma 4 | 4,679
glioblastoma 4 | 5,792
malignant mesothelioma 4 | 3,232
psoriasis 4 | 6,694
Anemia 3 | 365
Cachexia 3 | 50
Cerebellar Ataxia 3 | 304
Epilepsy 3 | 792
Multiple myeloma 3 | 1,332
Muscle Spasticity 3 | 195
Obesity 3 | 678
Prostatic Neoplasms 3 | 495
Seizures 3 | 596
Short stature 3 | 531
Small head 3 | 374
Stevens-Johnson syndrome 3 | 92
Trichothiodystrophy 1, photosensitive 3 | 4
Trichothiodystrophy Syndromes 3 | 6
Xeroderma pigmentosum group G 3 | 16
astrocytoma 3 | 1,146
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
progressive supranuclear palsy 3 | 676
pediatric high grade glioma 2 | 1,064

Tissue

Blood and immune system 22 | 16,909
Cardiovascular System 22 | 15,192
Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678

Target Family

Non-IDG 17 | 12,091
Enzyme 5 | 4,145

GO Process

nucleotide-excision repair, DN... 22 | 22
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
General transcription factor IIH subunit 2 GTF2H2 Tbio Non-IDG -1.32757 20.2 148
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.12534 131.4 181
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG -1.66231 61.9 139
TFIIH basal transcription factor complex helicase XPD subunit ERCC2 Tbio Enzyme -2.58326 365.8 191
DNA damage-binding protein 1 DDB1 Tbio Non-IDG -2.34719 202.5 353
UV excision repair protein RAD23 homolog B RAD23B Tbio Non-IDG -1.99412 96.8 313
Chromodomain-helicase-DNA-binding protein 1-like CHD1L Tbio Enzyme -2.22453 176.8 129
Cullin-4A CUL4A Tbio Non-IDG -1.92199 80.1 276