Development Level

Tbio 22 | 11,445
Tclin 1 | 613

IMPC Phenotype

abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal liver size 1 | 5
abnormal pericardium morpholog... 1 | 26
abnormal retinal inner nuclear... 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal thymus morphology 1 | 7
abnormal urinary bladder morph... 1 | 11
decreased bone mineral density 1 | 126
decreased circulating serum al... 1 | 82
decreased prepulse inhibition 1 | 82
decreased total retina thickne... 1 | 17
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hydrometra 1 | 53
improved glucose tolerance 1 | 79
increased body weight 1 | 25
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 36
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
small seminal vesicle 1 | 10
small spleen 1 | 19
small superior vagus ganglion 1 | 74
small thymus 1 | 16

Disease

ovarian cancer 18 | 8,520
Carcinoma 11 | 11,493
osteosarcoma 9 | 7,950
Cancer 8 | 2,499
Multiple myeloma 8 | 1,332
lung cancer 8 | 4,740
Cockayne syndrome 7 | 60
Xeroderma pigmentosum 7 | 43
malignant mesothelioma 6 | 3,232
medulloblastoma, large-cell 5 | 6,241
Breast cancer 4 | 3,578
Cryptorchidism 4 | 296
Hypogonadism 4 | 173
Melanoma 4 | 711
Stevens-Johnson syndrome 4 | 92
Waldenstrons macroglobulinemia 4 | 765
atypical teratoid / rhabdoid tumor 4 | 5,112
ependymoma 4 | 4,679
psoriasis 4 | 6,694
Anemia 3 | 365
Arthralgia 3 | 90
Atrophic condition of skin 3 | 25
Autosomal recessive predisposition 3 | 1,442
Basal cell carcinoma 3 | 54
Cataract 3 | 297
Conjunctival telangiectasis 3 | 14
Conjunctivitis 3 | 53
Conjunctivitis, recurrent 3 | 37
Defective DNA repair after ultraviolet radiation damage 3 | 7
Dental abnormalities 3 | 60
Developmental regression 3 | 95
Disease Progression 3 | 136
Dry skin 3 | 75
Ectropion 3 | 38
Electroencephalogram abnormal 3 | 101
Entropion 3 | 22
Erythema 3 | 58
Failure to gain weight 3 | 365
Fatigue 3 | 182
Fever 3 | 138
Flushing 3 | 60
Freckles 3 | 33
Hyperkeratosis 3 | 50
Hyperpigmented macules 3 | 42
Impaired cognition 3 | 96
Intellectual disability 3 | 1,016
Keratitis 3 | 62
Lens Opacities 3 | 231
Loss of developmental milestones 3 | 95
Mental deterioration in childhood 3 | 95
Mental impairment 3 | 95
Neurodevelopmental regression 3 | 95
Optic Atrophy 3 | 242
Papilloma 3 | 44
Pediatric failure to thrive 3 | 365
Photodysphoria 3 | 121
Photophobia 3 | 121
Photosensitivity of skin 3 | 51
Poikiloderma 3 | 14
Progressive mental retardation 3 | 37
Psychomotor regression 3 | 95
Psychomotor regression beginning in infancy 3 | 95
Psychomotor regression in infants 3 | 95
Psychomotor regression, progressive 3 | 95
Sensorineural Hearing Loss (disorder) 3 | 284
Spider Veins 3 | 17
Strabismus 3 | 270
Telangiectasia of the skin 3 | 39
Telangiectasis 3 | 36
Thin skin 3 | 47
Tooth Abnormalities 3 | 69
Xerosis 3 | 75
acute myeloid leukemia 3 | 783
astrocytic glioma 3 | 2,597
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
hypopigmented skin patch 3 | 59
progressive supranuclear palsy 3 | 676
tuberculosis and treatment for 6 months 3 | 409
Alzheimer's disease 2 | 658
Asthma 2 | 385
Dull intelligence 2 | 645
Epilepsy 2 | 792
Liver neoplasms 2 | 130
Mental deficiency 2 | 645
Poor school performance 2 | 645
Prostatic Neoplasms 2 | 495
Schizophrenia 2 | 1,160
Seizures 2 | 596
Stomach Neoplasms 2 | 300
acute quadriplegic myopathy 2 | 1,158
astrocytoma 2 | 1,146
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
primitive neuroectodermal tumor 2 | 3,035

Tissue

Blood and immune system 23 | 16,909
Cardiovascular System 23 | 15,192
Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Skin and soft tissues 23 | 17,230
Urinary Tract 23 | 16,678

Target Family

Non-IDG 21 | 12,091
Enzyme 2 | 4,145

GO Process

nucleotide-excision repair, DN... 23 | 23
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
COP9 signalosome complex subunit 4 COPS4 Tbio Non-IDG -0.91181 7.39 88
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
COP9 signalosome complex subunit 7a COPS7A Tbio Non-IDG -1.50943 32.2 154
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG -1.66231 61.9 139
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.12534 131.4 181
DNA damage-binding protein 1 DDB1 Tbio Non-IDG -2.34719 202.5 353
COP9 signalosome complex subunit 1 GPS1 Tbio Non-IDG -1.62973 42.8 246
Cullin-4A CUL4A Tbio Non-IDG -1.92199 80.1 276
DNA repair protein complementing XP-C cells XPC Tbio Non-IDG -2.21142 154.0 208