Development Level

Tbio 30 | 10,625
Tchem 3 | 1,890
Tdark 2 | 7,003

IMPC Phenotype

embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
increased mean corpuscular vol... 2 | 91
preweaning lethality, complete... 2 | 633
abnormal cornea morphology 1 | 24
abnormal cranium morphology 1 | 32
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal placement of pupils 1 | 4
abnormal retina morphology 1 | 100
anophthalmia 1 | 20
corneal opacity 1 | 25
decreased body weight 1 | 174
increased bone mineral density 1 | 52
increased circulating aspartat... 1 | 17
increased circulating potassiu... 1 | 31
increased heart weight 1 | 37
narrow eye opening 1 | 15
thrombocytopenia 1 | 46

Disease

ovarian cancer 23 | 8,491
osteosarcoma 21 | 7,933
Xeroderma pigmentosum 16 | 41
Cancer 13 | 2,346
Cockayne syndrome 12 | 54
psoriasis 12 | 6,685
lung cancer 11 | 4,473
Breast cancer 10 | 3,098
glioblastoma 10 | 5,572
medulloblastoma, large-cell 10 | 6,234
malignant mesothelioma 8 | 3,163
Fanconi's anemia 7 | 50
Peripheral Neuropathy 7 | 303
Photosensitive trichothiodystrophy 7 | 24
atypical teratoid / rhabdoid tumor 7 | 4,369
pediatric high grade glioma 7 | 2,712
Stomach Neoplasms 5 | 282
group 3 medulloblastoma 5 | 2,254
nasopharyngeal carcinoma 5 | 1,056
primitive neuroectodermal tumor 5 | 3,031
sonic hedgehog group medulloblastoma 5 | 1,482
Anemia 4 | 252
Arsenic Poisoning 4 | 59
Fanconi Anemia 4 | 22
Prostatic Neoplasms 4 | 471
esophageal atresia/tracheoesophageal fistula 4 | 19
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
non primary Sjogren syndrome sicca 4 | 840
oligodendroglioma 4 | 2,849
pancreatic carcinoma 4 | 567
Bladder Neoplasm 3 | 109
Carcinoma 3 | 2,147
Hereditary Breast and Ovarian Cancer Syndrome 3 | 14
Lung Neoplasms 3 | 171
Lynch syndrome 3 | 35
Neoplasm Metastasis 3 | 138
Neoplastic Syndromes, Hereditary 3 | 48
Pick disease 3 | 1,893
Trichothiodystrophy 1, photosensitive 3 | 4
Trichothiodystrophy Syndromes 3 | 5
Waldenstrons macroglobulinemia 3 | 764
Xeroderma pigmentosum-Cockayne syndrome complex 3 | 4
astrocytoma 3 | 1,493
atypical teratoid/rhabdoid tumor 3 | 1,095
dermatomyositis 3 | 966
diabetes mellitus 3 | 1,663
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
lung adenocarcinoma 3 | 2,714
pancreatic cancer 3 | 2,300
pituitary cancer 3 | 1,972
posterior fossa group A ependymoma 3 | 1,511
subependymal giant cell astrocytoma 3 | 2,287
Adenocarcinoma of lung (disorder) 2 | 48
Ataxia telangiectasia 2 | 32
Baller-Gerold syndrome 2 | 14
Bloom syndrome 2 | 30
Cataract 2 | 104
Chromosome Aberrations 2 | 15
Colorectal Neoplasms 2 | 217
Disease Progression 2 | 125
Glioma 2 | 66
Li-Fraumeni syndrome 2 | 13
Machado-Joseph disease 2 | 18
Male infertility 2 | 170
Malignant neoplasm of lung 2 | 16
Malignant neoplasm of prostate 2 | 67
Mammary Neoplasms 2 | 410
Melanoma 2 | 261
Micronuclei, Chromosome-Defective 2 | 20
Multiple myeloma 2 | 1,327
Neoplasms, Germ Cell and Embryonal 2 | 13
Neurodegenerative disease 2 | 383
Nijmegen breakage syndrome 2 | 23
Pancreatic Neoplasm 2 | 79
Pancreatic carcinoma, familial 2 | 8
Peutz-Jeghers syndrome 2 | 23
Polycystic Ovary Syndrome 2 | 334
Prostate cancer 2 | 172
Rheumatoid Arthritis 2 | 1,170
Rothmund-Thomson syndrome 2 | 22
Schizophrenia 2 | 503
Skin Neoplasms 2 | 49
Skin benign neoplasm 2 | 5
Squamous cell carcinoma 2 | 96
Testicular Neoplasms 2 | 5
adrenocortical carcinoma 2 | 1,427
astrocytic glioma 2 | 2,241
chronic lymphocytic leukemia 2 | 244
colon cancer 2 | 1,475
glioblastoma multiforme 2 | 347
hepatocellular carcinoma 2 | 550
invasive ductal carcinoma 2 | 2,950
lung carcinoma 2 | 2,844
medulloblastoma 2 | 1,524
non-small cell lung carcinoma 2 | 413
ovarian neoplasm 2 | 97
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
pilocytic astrocytoma 2 | 3,086

Tissue

Blood and immune system 35 | 17,994
Cardiovascular System 35 | 17,957
Digestive Tract 35 | 18,472
Endocrine System 35 | 18,511
Female tissues 35 | 18,646
Liver and Pancreas 35 | 18,135
Male tissues 35 | 17,968
Nervous System 35 | 18,560
Respiratory system 35 | 17,483
Skin and soft tissues 35 | 18,114
Urinary Tract 35 | 18,443

Target Family

Non-IDG 23 | 11,969
Enzyme 10 | 4,146
Transcription Factor 1 | 1,400
Transporter 1 | 473

GO Process

nucleotide-excision repair 35 | 35
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA repair protein complementing XP-C cells XPC Tbio Non-IDG -2.18675 151.0 193
General transcription factor IIH subunit 3 GTF2H3 Tbio Non-IDG -0.87291 6.02 65
Fanconi anemia group C protein FANCC Tbio Non-IDG -2.81714 629.4 323
MMS19 nucleotide excision repair protein homolog MMS19 Tbio Non-IDG -1.63430 40.6 112
Ataxin-3 ATXN3 Tbio Non-IDG -2.85838 721.6 233
DNA excision repair protein ERCC-1 ERCC1 Tbio Non-IDG -3.01167 969.9 606
Replication protein A 30 kDa subunit RPA4 Tbio Non-IDG -1.32394 20.7 110
DNA damage-binding protein 2 DDB2 Tbio Non-IDG -2.05065 116.6 146
General transcription factor IIH subunit 5 GTF2H5 Tbio Non-IDG -1.62240 36.4 42
Endonuclease 8-like 2 NEIL2 Tbio Enzyme -1.70662 46.9 91