Development Level

Tbio 108 | 11,445
Tdark 5 | 6,588
Tchem 4 | 1,598

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
decreased body length 2 | 101
embryonic growth retardation 2 | 106
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal pericardium morpholog... 1 | 26
abnormal vitreous body morphol... 1 | 10
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
exencephaly 1 | 2
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
increased cardiac muscle contr... 1 | 8
increased heart weight 1 | 62
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
prenatal lethality 1 | 28
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38

Disease

ovarian cancer 52 | 8,520
lung cancer 38 | 4,740
Carcinoma 30 | 11,493
diabetes mellitus 28 | 1,728
Multiple myeloma 27 | 1,332
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,291
medulloblastoma, large-cell 27 | 6,241
osteosarcoma 26 | 7,950
Diamond-Blackfan anemia 24 | 31
psoriasis 21 | 6,694
Breast cancer 18 | 3,578
group 3 medulloblastoma 18 | 4,104
Waldenstrons macroglobulinemia 17 | 765
Anemia 15 | 365
Cleft Palate 15 | 271
acute quadriplegic myopathy 15 | 1,158
glioblastoma 15 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
Uranostaphyloschisis 14 | 167
atypical teratoid / rhabdoid tumor 14 | 5,112
Abnormality of the urinary system 13 | 21
Anemia, Diamond-Blackfan 13 | 16
Anemia, Macrocytic 13 | 18
Cardiac Arrhythmia 13 | 103
Cardiac conduction abnormalities 13 | 78
Conduction disorder of the heart 13 | 79
Delayed Puberty 13 | 97
EKG abnormalities 13 | 78
Electrocardiogram abnormal 13 | 81
Electrocardiogram change 13 | 78
Fatigue 13 | 182
Hand deformities 13 | 32
Intermittent migraine headaches 13 | 68
Migraine Disorders 13 | 76
Pallor 13 | 40
genital abnormal 13 | 17
reproductive system abnormality 13 | 17
malignant mesothelioma 12 | 3,232
cystic fibrosis 10 | 1,696
Disease Progression 9 | 136
Kidney cancer 9 | 2,613
Stomach Neoplasms 9 | 300
astrocytoma 9 | 1,146
invasive ductal carcinoma 9 | 2,951
sonic hedgehog group medulloblastoma 9 | 467
acute myeloid leukemia 8 | 783
lung adenocarcinoma 8 | 2,716
Breast Neoplasms 7 | 445
Cancer 7 | 2,499
Mammary Neoplasms 7 | 425
adult high grade glioma 7 | 3,801
breast carcinoma 7 | 1,638
mucosa-associated lymphoid tissue lymphoma 7 | 484
oligodendroglioma 7 | 2,850
subependymal giant cell astrocytoma 7 | 2,287
Adenocarcinoma of lung 6 | 142
Disease Models, Animal 6 | 155
Intellectual disability 6 | 1,016
ependymoma 6 | 4,679
non-small cell lung cancer 6 | 2,890
primitive neuroectodermal tumor 6 | 3,035
Cognitive delay 5 | 608
Global developmental delay 5 | 608
Infantile onset 5 | 238
Mental and motor retardation 5 | 608
Reticulocytopenia 5 | 10
Rheumatoid arthritis 5 | 1,191
Short stature 5 | 531
aldosterone-producing adenoma 5 | 665
colon cancer 5 | 1,478
group 4 medulloblastoma 5 | 1,855
spina bifida 5 | 1,074
Amyotrophic lateral sclerosis 4 | 451
Autosomal recessive predisposition 4 | 1,442
Hemoglobin low 4 | 124
Hereditary spherocytosis type 4 4 | 18
Hypoplastic mandible condyle 4 | 275
Mandibular hypoplasia 4 | 275
Microcephaly 4 | 166
Micrognathism 4 | 275
Parkinson Disease 4 | 64
Pick disease 4 | 1,894
Ventricular Septal Defects 4 | 119
astrocytic glioma 4 | 2,597
inflammatory breast cancer 4 | 286
lung carcinoma 4 | 2,843
medulloblastoma 4 | 720
progressive supranuclear palsy 4 | 676
tuberculosis and treatment for 6 months 4 | 409
Astrocytoma, Pilocytic 3 | 3,081
Polycystic ovary syndrome 3 | 360
Prostatic Neoplasms 3 | 495
adrenocortical carcinoma 3 | 1,428
cutaneous lupus erythematosus 3 | 1,057
juvenile dermatomyositis 3 | 1,187
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
primary pancreatic ductal adenocarcinoma 3 | 1,109

Tissue

Blood and immune system 117 | 16,909
Digestive Tract 117 | 17,369
Endocrine System 117 | 18,159
Female tissues 117 | 17,400
Liver and Pancreas 117 | 16,750
Male tissues 117 | 17,142
Nervous System 117 | 16,725
Respiratory system 117 | 16,393
Skin and soft tissues 117 | 17,230
Cardiovascular System 116 | 15,192
Urinary Tract 116 | 16,678

Target Family

Non-IDG 106 | 12,091
Enzyme 10 | 4,145
Kinase 1 | 634

GO Process

nuclear-transcribed mRNA catab... 117 | 117
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
60S ribosomal protein L3 RPL3 Tbio Non-IDG -2.02901 103.9 190
40S ribosomal protein S19 RPS19 Tbio Non-IDG -3.14746 1380.8 267
60S ribosomal protein L36 RPL36 Tbio Non-IDG -1.62928 39.9 123
RNA-binding protein 8A RBM8A Tbio Non-IDG -3.16448 1415.1 94
Exosome component 10 EXOSC10 Tbio Non-IDG -2.45249 279.1 123
Serine/threonine-protein kinase SMG1 SMG1 Tchem Kinase -1.61615 60.9 195
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A GSPT1 Tbio Enzyme -1.35573 22.8 99
60S ribosomal protein L35 RPL35 Tbio Non-IDG -1.30696 19.1 124
60S ribosomal protein L10 RPL10 Tbio Non-IDG -0.94919 8.10 191
Telomerase-binding protein EST1A SMG6 Tbio Enzyme -1.48788 32.6 37