Development Level

Tbio 16 | 11,445
Tdark 5 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal body wall morphology 1 | 9
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
enlarged spleen 1 | 41
female infertility 1 | 60
hyperactivity 1 | 148
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased fasted circulating g... 1 | 76
increased leukocyte cell numbe... 1 | 47
male infertility 1 | 123
protruding tongue 1 | 3
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

osteosarcoma 15 | 7,950
Carcinoma 13 | 11,493
ovarian cancer 11 | 8,520
atypical teratoid / rhabdoid tumor 8 | 5,112
psoriasis 8 | 6,694
ependymoma 7 | 4,679
lung cancer 7 | 4,740
Emery-Dreifuss muscular dystrophy 6 | 23
glioblastoma 6 | 5,792
medulloblastoma, large-cell 5 | 6,241
Astrocytoma, Pilocytic 4 | 3,081
Breast cancer 4 | 3,578
Progeria 4 | 25
diabetes mellitus 4 | 1,728
group 3 medulloblastoma 4 | 4,104
malignant mesothelioma 4 | 3,232
pancreatic cancer 4 | 2,398
Atrial Fibrillation 3 | 124
Autosomal recessive predisposition 3 | 1,442
Contracture 3 | 96
Contracture of joint 3 | 93
Failure to gain weight 3 | 365
Fetal Growth Retardation 3 | 189
Flexion contracture 3 | 93
Flexion contractures of joints 3 | 93
Hyperkyphosis 3 | 111
Infant, Small for Gestational Age 3 | 176
Intrauterine retardation 3 | 176
Joint stiffness 3 | 84
Kyphosis deformity of spine 3 | 114
Lipodystrophy 3 | 40
Muscle hypotonia 3 | 571
Orbital separation excessive 3 | 244
Pediatric failure to thrive 3 | 365
Polyhydramnios 3 | 108
Reduced fetal movement 3 | 51
Short stature 3 | 531
acute quadriplegic myopathy 3 | 1,158
astrocytic glioma 3 | 2,597
oligodendroglioma 3 | 2,850
primary pancreatic ductal adenocarcinoma 3 | 1,109
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
Abnormal urinary amino-acid findings 2 | 38
Absence of pubertal development 2 | 17
Absent eyelashes 2 | 16
Acanthosis Nigricans 2 | 27
Acro-Osteolysis 2 | 12
Aminoaciduria 2 | 38
Aplasia of eyelashes 2 | 16
Aplasia/Hypoplasia of the earlobes 2 | 10
Atrophic condition of skin 2 | 25
Auricular malformation 2 | 41
Bird-like facies 2 | 4
Brachyonychia 2 | 6
Bullet vertebral body 2 | 17
Calcinosis 2 | 70
Choanal Atresia 2 | 42
Congenital hypoplasia of clavicle 2 | 18
Convex nasal ridge 2 | 37
Decreased testosterone in males 2 | 28
Dry Eye Syndromes 2 | 8
Failure of development of eyelashes 2 | 16
Fetal Membranes, Premature Rupture 2 | 5
High pitched voice 2 | 23
Hyperglycemia 2 | 137
Hypernasal voice 2 | 39
Hyperphosphatemia (disorder) 2 | 17
Insulin resistant diabetes 2 | 13
Keratitis sicca 2 | 6
Keratoconjunctivitis sicca 2 | 25
Kyphoscoliosis deformity of spine 2 | 60
Lack of skin elasticity 2 | 10
Lordosis 2 | 54
Low serum estradiol levels 2 | 22
Metaphyseal widening 2 | 22
Mottled pigmentation 2 | 4
Nasal voice 2 | 39
Ovoid vertebral bodies 2 | 17
Premature canities 2 | 24
Reticular pigmentation pattern 2 | 7
Reticulate skin pigmentation 2 | 7
SERUM PHOSPHATE ELEVATED 2 | 14
Scleroderma 2 | 7
Scleroderma-like secondary cutaneous sclerosis 2 | 7
Short distal phalanges 2 | 50
Simple ear 2 | 41
Skin Erosion 2 | 12
Sparse eyebrow 2 | 42
Sparse eyelashes 2 | 31
Steatohepatitis 2 | 44
Stillbirth 2 | 17
Stippled pigmentation 2 | 4
Stretched skin 2 | 10
Submucous cleft of hard palate 2 | 11
Submucous clefting 2 | 9
Tapering pointed ends of distal finger phalanges 2 | 3
Thin nails 2 | 5
Widely patent fontanels and sutures 2 | 12
Xerophthalmia 2 | 16

Tissue

Endocrine System 22 | 18,159
Blood and immune system 21 | 16,909
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Nervous System 21 | 16,725
Skin and soft tissues 21 | 17,230
Digestive Tract 20 | 17,369
Respiratory system 20 | 16,393
Urinary Tract 20 | 16,678
Cardiovascular System 19 | 15,192

Target Family

Non-IDG 18 | 12,091
Enzyme 3 | 4,145
Kinase 1 | 634

GO Process

nuclear envelope organization 22 | 22
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
Inner nuclear membrane protein Man1 LEMD3 Tbio Non-IDG -2.30311 196.6 73
Transmembrane protein 170A TMEM170A Tdark Non-IDG 0.00000 1.18 3
Myotonin-protein kinase DMPK Tchem Kinase -2.70945 496.6 196
Transmembrane protein 201 TMEM201 Tdark Non-IDG -2.07296 119.8 17
Sperm-associated antigen 4 protein SPAG4 Tdark Non-IDG -1.24413 17.4 48
CAAX prenyl protease 1 homolog ZMPSTE24 Tbio Enzyme -2.10187 125.8 321
Nuclear pore complex protein Nup93 NUP93 Tbio Non-IDG -1.35565 22.2 62
Ankyrin repeat and LEM domain-containing protein 1 ANKLE1 Tbio Non-IDG -1.22574 16.7 31
LEM domain-containing protein 2 LEMD2 Tdark Non-IDG -0.53782 3.95 95