Development Level

Tbio 5 | 11,445

Collection

GPCR: IDG Consortium (Targets) 1 | 126

Disease

Carcinoma 5 | 11,493
ovarian cancer 5 | 8,520
psoriasis 4 | 6,694
Breast cancer 3 | 3,578
atypical teratoid / rhabdoid tumor 3 | 5,112
breast carcinoma 3 | 1,638
cystic fibrosis 3 | 1,696
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
interstitial cystitis 3 | 2,312
lung cancer 3 | 4,740
non-small cell lung cancer 3 | 2,890
osteosarcoma 3 | 7,950
Autosomal dominant Robinow syndrome 1 2 | 15
Cancer 2 | 2,499
Robinow Syndrome, Autosomal Dominant 2 | 3
Robinow syndrome 2 | 11
astrocytic glioma 2 | 2,597
colon cancer 2 | 1,478
ductal carcinoma in situ 2 | 1,745
fibroadenoma 2 | 559
medulloblastoma, large-cell 2 | 6,241
Abnormal iris vasculature 1 | 2
Anteverted nostril 1 | 191
Atopic dermatitis 1 | 952
Autosomal dominant nonsyndromic deafness 25 1 | 6
Big calvaria 1 | 147
Blindness 1 | 88
Brachydactyly 1 | 156
Broad flat nasal bridge 1 | 236
Broad thumbs 1 | 28
Cell Transformation, Neoplastic 1 | 97
Clitoral hypoplasia 1 | 11
Decreased projection of midface 1 | 105
Delayed bone age 1 | 136
Downward slant of palpebral fissure 1 | 158
Exophthalmos 1 | 112
Female Urogenital Diseases 1 | 18
Flat face 1 | 52
Frontal bossing 1 | 157
GLAUCOMA 1, OPEN ANGLE, A 1 | 3
GLAUCOMA 3, PRIMARY CONGENITAL, A 1 | 4
Gingival Hyperplasia 1 | 34
Gingival Hypertrophy 1 | 34
Gingival Overgrowth 1 | 36
Glaucoma of childhood 1 | 2
Glaucoma, Open-Angle 1 | 11
Hernia, Inguinal 1 | 89
Hydronephrosis 1 | 89
Hydrophthalmos 1 | 19
Hypotrophic malar bone 1 | 129
Hypotrophic midface 1 | 105
Inadequate arch length for tooth size 1 | 45
Increased head circumference 1 | 147
Increased size of cranium 1 | 147
Increased size of skull 1 | 147
Late tooth eruption 1 | 61
Liver Cirrhosis, Experimental 1 | 769
Long palpebral fissure 1 | 17
Long philtrum 1 | 137
Lung Neoplasms 1 | 232
Macroglossia 1 | 65
Malar flattening 1 | 129
Midface retrusion 1 | 105
Myopia 1 | 176
Nasal bridge wide 1 | 236
Neoplastic Cell Transformation 1 | 89
Ocular hypertension 1 | 42
Optic nerve disease 1 | 10
Pectus excavatum 1 | 100
Pigment dispersion syndrome 1 | 11
Posteriorly rotated ear 1 | 61
Primary open angle glaucoma juvenile onset 1 1 | 2
Prominent eyes 1 | 96
Prominent globes 1 | 96
Protruding eyes 1 | 96
Short hands 1 | 50
Small midface 1 | 105
Thin upper lip vermilion 1 | 67
Tooth Crowding 1 | 45
Tooth mass arch size discrepancy 1 | 45
Tooth size discrepancy 1 | 45
Umbilical hernia 1 | 93
Uterine Cervical Neoplasm 1 | 25
Uterine Cervical Neoplasms 1 | 26
Ventricular Outflow Obstruction, Right 1 | 3
Wide anterior fontanel 1 | 44
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
acute quadriplegic myopathy 1 | 1,158
astrocytoma 1 | 1,146
chronic kidney disease 1 | 90
head and neck cancer 1 | 271
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
medulloblastoma 1 | 720
nasopharyngeal carcinoma 1 | 1,058
pituitary cancer 1 | 1,972
primary congenital glaucoma 1 | 5
primary open angle glaucoma 1 | 16
tuberculosis 1 | 2,010

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Non-IDG 3 | 12,091
GPCR 2 | 408

GO Process

non-canonical Wnt signaling pa... 5 | 5
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myocilin MYOC Tbio Non-IDG -2.65916 482.8 169
Frizzled-7 FZD7 Tbio GPCR -1.81873 66.4 345
Protein Wnt-5a WNT5A Tbio Non-IDG -2.77525 650.2 321
Frizzled-10 FZD10 Tbio GPCR -1.39120 24.2 172
Segment polarity protein dishevelled homolog DVL-3 DVL3 Tbio Non-IDG -1.54019 31.2 206