Development Level

Tbio 3 | 11,445
Tclin 1 | 613

IMPC Phenotype

abnormal allantois morphology 1 | 8
abnormal heart morphology 1 | 162
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
decreased fasted circulating g... 1 | 65
embryonic lethality prior to o... 1 | 239
male infertility 1 | 123
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 4 | 11,493
ovarian cancer 4 | 8,520
Astrocytoma, Pilocytic 3 | 3,081
Breast cancer 3 | 3,578
Schizophrenia 3 | 1,160
Waldenstrons macroglobulinemia 3 | 765
glioblastoma 3 | 5,792
invasive ductal carcinoma 3 | 2,951
lung cancer 3 | 4,740
medulloblastoma, large-cell 3 | 6,241
ulcerative colitis 3 | 1,819
Bipolar Disorder 2 | 666
Duchenne muscular dystrophy 2 | 601
acute quadriplegic myopathy 2 | 1,158
aldosterone-producing adenoma 2 | 665
atypical teratoid / rhabdoid tumor 2 | 5,112
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 4,679
gastric cancer 2 | 459
group 3 medulloblastoma 2 | 4,104
lung adenocarcinoma 2 | 2,716
malignant mesothelioma 2 | 3,232
oligodendroglioma 2 | 2,850
osteosarcoma 2 | 7,950
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
psoriasis 2 | 6,694
spina bifida 2 | 1,074
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
Acquired immunodeficiency syndrome 1 | 197
Adenocarcinoma of lung 1 | 142
Alcoholic Intoxication, Chronic 1 | 289
Amphetamine-Related Disorders 1 | 74
Amyotrophic lateral sclerosis 1 | 451
Animal Mammary Neoplasms 1 | 136
Arsenic Poisoning 1 | 62
Atopic dermatitis 1 | 952
Autistic Disorder 1 | 364
Cancer 1 | 2,499
Carcinoma, Squamous Cell 1 | 110
Chronic obstructive pulmonary disease 1 | 184
Congenital heart disease 1 | 93
Craniofacial Abnormalities 1 | 151
Depressive disorder 1 | 409
Dermatologic disorders 1 | 93
Disease of anatomical entity 1 | 32
Down syndrome 1 | 499
Dysuria 1 | 26
Esophageal Squamous Cell Carcinoma 1 | 77
Heart disease 1 | 306
Homocystinuria 1 | 21
Hyperhomocysteinemia 1 | 37
Hypertension 1 | 396
Kidney Diseases 1 | 114
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Liver Cirrhosis, Experimental 1 | 769
Lymphoid leukemia 1 | 160
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Megaloblastic anemia 1 | 18
Mental Depression 1 | 333
Methylmalonic acidemia 1 | 37
Mouth Neoplasms 1 | 55
Myocardial Ischemia 1 | 169
Neoplasm Invasiveness 1 | 161
Neoplasm Metastasis 1 | 168
Neural Tube Defects 1 | 31
Neural tube defect, folate-sensitive 1 | 4
Orofacial cleft 1 | 54
Peripheral vascular disease 1 | 87
Skin Diseases 1 | 71
Squamous cell carcinoma 1 | 129
Squamous cell carcinoma of esophagus 1 | 77
Type 2 diabetes mellitus 1 | 272
Urinary Incontinence 1 | 50
Urinary Tract Irritation 1 | 24
active Crohn's disease 1 | 922
astrocytoma 1 | 1,146
atypical teratoid/rhabdoid tumor 1 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
chronic lymphosyte leukemia 1 | 204
chronic rhinosinusitis 1 | 512
colon cancer 1 | 1,478
esophageal adenocarcinoma 1 | 737
fascioscapulohumeral muscular dystrophy 1 | 100
fibroadenoma 1 | 559
head and neck cancer 1 | 271
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
nasopharyngeal carcinoma 1 | 1,058
neural tube defect 1 | 9
pancreatic carcinoma 1 | 562
pediatric high grade glioma 1 | 1,064
posterior fossa group B ependymoma 1 | 416
progressive supranuclear palsy 1 | 676

Tissue

Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Enzyme 2 | 4,145
Non-IDG 2 | 12,091

GO Process

neutrophil homeostasis 4 | 4
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B Tclin Enzyme -2.13222 124.3 341
C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 Tbio Enzyme -1.97029 90.6 101
Junctional adhesion molecule C JAM3 Tbio Non-IDG -1.93757 97.1 251
Annexin A1 ANXA1 Tbio Non-IDG -2.90864 897.0 765