Development Level

Tbio 350 | 11,651
Tchem 93 | 1,388
Tclin 22 | 612
Tdark 19 | 6,593

Collection

RFA-RM-18-021 4 | 328
GPCR: IDG Consortium (Complete... 2 | 25
GPCR: IDG Consortium (Targets) 2 | 126
Ion Channel: IDG Consortium (T... 2 | 99
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 27 | 979
preweaning lethality, incomple... 16 | 499
decreased vertical activity 9 | 208
embryonic lethality prior to t... 9 | 278
abnormal behavior 7 | 298
embryonic lethality prior to o... 7 | 239
short tibia 7 | 97
abnormal embryo size 6 | 220
cataract 5 | 92
decreased bone mineral density 5 | 126
decreased circulating insulin ... 5 | 76
decreased total body fat amoun... 5 | 207
increased circulating alkaline... 5 | 122
increased lean body mass 5 | 172
abnormal retina morphology 4 | 71
abnormal seminal vesicle morph... 4 | 114
decreased bone mineral content 4 | 151
decreased caudal vertebrae num... 4 | 53
enlarged lymph nodes 4 | 37
hyperactivity 4 | 148
hypoactivity 4 | 132
increased bone mineral content 4 | 108
increased bone mineral density 4 | 72
increased leukocyte cell numbe... 4 | 47
abnormal bone structure 3 | 187
abnormal heart morphology 3 | 162
abnormal lens morphology 3 | 81
decreased circulating choleste... 3 | 93
decreased circulating serum al... 3 | 82
enlarged heart 3 | 210
impaired glucose tolerance 3 | 75
increased circulating creatini... 3 | 38
increased circulating sodium l... 3 | 71
increased mean corpuscular vol... 3 | 92
abnormal coat appearance 2 | 31
abnormal kidney morphology 2 | 65
abnormal lung morphology 2 | 26
abnormal retinal vasculature m... 2 | 27
decreased circulating HDL chol... 2 | 68
decreased circulating amylase ... 2 | 28
decreased circulating bilirubi... 2 | 19
decreased circulating total pr... 2 | 49
decreased circulating triglyce... 2 | 79
decreased lean body mass 2 | 135
decreased mean corpuscular hem... 2 | 50
decreased threshold for audito... 2 | 26
edema 2 | 59
embryonic growth retardation 2 | 106
increased circulating chloride... 2 | 41
increased circulating free fat... 2 | 20
increased circulating potassiu... 2 | 29
increased circulating thyroxin... 2 | 7
increased circulating total pr... 2 | 28
increased circulating triglyce... 2 | 42
increased mean corpuscular hem... 2 | 36
increased or absent threshold ... 2 | 101
increased spleen weight 2 | 10
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
prenatal lethality 2 | 28
small adrenal glands 2 | 16
small superior vagus ganglion 2 | 74
abnormal behavioral response t... 1 | 66
abnormal cornea morphology 1 | 31
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal neural tube closure 1 | 46
abnormal testis morphology 1 | 43
absent pinna reflex 1 | 23
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased circulating calcium ... 1 | 36
decreased circulating sodium l... 1 | 22
decreased fluid intake 1 | 3
decreased food intake 1 | 13
decreased grip strength 1 | 116
decreased mean corpuscular hem... 1 | 31
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
hydrometra 1 | 53
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased cardiac muscle contr... 1 | 8
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating fructosa... 1 | 13
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 26
increased heart weight 1 | 62
limb grasping 1 | 41
long tibia 1 | 25
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
stereotypic behavior 1 | 3
thrombocytosis 1 | 27
trunk curl 1 | 16

Disease

osteosarcoma 295 | 7,950
ovarian cancer 290 | 8,519
Carcinoma 278 | 11,493
psoriasis 209 | 6,694
lung cancer 201 | 4,740
glioblastoma 189 | 5,792
medulloblastoma, large-cell 167 | 6,241
lung carcinoma 144 | 2,843
Cancer 137 | 2,499
non-small cell lung cancer 137 | 2,890
atypical teratoid / rhabdoid tumor 128 | 5,112
tuberculosis 128 | 2,010
malignant mesothelioma 127 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 125 | 3,290
Breast cancer 123 | 3,577
interstitial cystitis 120 | 2,312
Astrocytoma, Pilocytic 118 | 3,081
lung adenocarcinoma 116 | 2,716
ependymoma 114 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 112 | 2,954
subependymal giant cell astrocytoma 111 | 2,287
invasive ductal carcinoma 110 | 2,950
pancreatic cancer 109 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 108 | 2,988
adult high grade glioma 106 | 3,801
group 3 medulloblastoma 98 | 4,104
diabetes mellitus 96 | 1,728
ulcerative colitis 92 | 1,819
pancreatic ductal adenocarcinoma liver metastasis 89 | 1,962
Multiple myeloma 86 | 1,332
mucosa-associated lymphoid tissue lymphoma 83 | 484
Waldenstrons macroglobulinemia 79 | 765
astrocytoma 73 | 1,146
cutaneous lupus erythematosus 73 | 1,057
Autosomal recessive predisposition 70 | 1,442
Rheumatoid arthritis 66 | 1,191
oligodendroglioma 65 | 2,850
Liver Cirrhosis, Experimental 64 | 769
cystic fibrosis 64 | 1,695
juvenile dermatomyositis 64 | 1,187
Kidney cancer 62 | 2,613
dermatomyositis 62 | 966
acute quadriplegic myopathy 61 | 1,158
primitive neuroectodermal tumor 61 | 3,035
primary pancreatic ductal adenocarcinoma 59 | 1,108
breast carcinoma 57 | 1,637
colon cancer 53 | 1,478
astrocytic glioma 51 | 2,597
esophageal adenocarcinoma 50 | 737
Pick disease 49 | 1,894
ductal carcinoma in situ 49 | 1,744
pituitary cancer 49 | 1,972
group 4 medulloblastoma 47 | 1,855
Duchenne muscular dystrophy 45 | 601
adrenocortical carcinoma 44 | 1,428
Atopic dermatitis 43 | 952
Schizophrenia 43 | 1,160
nasopharyngeal carcinoma 43 | 1,058
gastric carcinoma 41 | 807
Alzheimer's disease 40 | 658
primary Sjogren syndrome 40 | 735
non primary Sjogren syndrome sicca 38 | 891
Kidney disease 36 | 430
active Crohn's disease 36 | 922
active ulcerative colitis 36 | 764
pediatric high grade glioma 36 | 1,064
Arthritis 35 | 290
periodontitis 34 | 293
Intellectual disability 33 | 1,016
Asthma 31 | 385
Hepatomegaly 31 | 285
Splenomegaly 31 | 190
spina bifida 31 | 1,074
Epilepsy 30 | 792
Seizures 30 | 596
Vascular disease 29 | 319
acute myeloid leukemia 28 | 783
Hypertension 27 | 396
Neurodegenerative disease 27 | 414
Anemia 26 | 365
Dull intelligence 26 | 645
Low intelligence 26 | 645
Mental Retardation 26 | 645
Mental deficiency 26 | 645
Multiple Sclerosis 26 | 540
Muscle hypotonia 26 | 571
Poor school performance 26 | 645
Prostatic Neoplasms 26 | 495
hepatocellular carcinoma 26 | 547
Atherosclerosis 25 | 291
Obesity 25 | 678
chronic lymphosyte leukemia 25 | 204
nephrosclerosis 25 | 333
pancreatic carcinoma 25 | 562
Melanoma 23 | 711
head and neck cancer and chronic obstructive pulmonary disease 23 | 239
Lung disease 22 | 142
autosomal dominant Emery-Dreifuss muscular dystrophy 22 | 510
gastric cancer 22 | 459
Down syndrome 21 | 499

Tissue

Blood and immune system 477 | 16,909
Female tissues 477 | 17,400
Skin and soft tissues 477 | 17,230
Digestive Tract 476 | 17,369
Endocrine System 474 | 18,159
Liver and Pancreas 473 | 16,750
Respiratory system 468 | 16,393
Urinary Tract 468 | 16,678
Male tissues 465 | 17,142
Nervous System 459 | 16,725
Cardiovascular System 449 | 15,192

Target Family

Non-IDG 255 | 12,091
Enzyme 181 | 4,145
Kinase 14 | 634
Transporter 12 | 473
GPCR 11 | 408
Ion Channel 9 | 344
Transcription Factor 2 | 1,400

GO Process

neutrophil degranulation 484 | 484
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myeloperoxidase MPO Tchem Enzyme -3.51470 3209.3 1255
Cytoplasmic FMR1-interacting protein 1 CYFIP1 Tbio Non-IDG -1.46134 28.5 64
Cysteine-rich secretory protein 3 CRISP3 Tbio Non-IDG -1.58618 43.2 129
Desmoglein-1 DSG1 Tbio Non-IDG -2.72159 516.2 406
Peroxiredoxin-4 PRDX4 Tbio Non-IDG -2.02710 109.0 300
Coatomer subunit beta COPB1 Tbio Non-IDG -1.94049 82.6 148
Drebrin-like protein DBNL Tbio Non-IDG -1.16567 21.1 172
Vesicle-associated membrane protein 8 VAMP8 Tbio Non-IDG -1.79654 64.6 107
Cytoplasmic dynein 1 light intermediate chain 1 DYNC1LI1 Tbio Non-IDG -1.67860 45.9 100
ATP-dependent 6-phosphofructokinase, liver type PFKL Tbio Kinase -2.07015 107.6 240