Development Level

Tbio 44 | 11,651
Tchem 11 | 1,388
Tclin 6 | 612

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 3 | 499
decreased vertical activity 2 | 208
improved glucose tolerance 2 | 79
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
decreased caudal vertebrae num... 1 | 53
decreased circulating alanine ... 1 | 47
decreased circulating insulin ... 1 | 76
decreased circulating magnesiu... 1 | 13
decreased circulating phosphat... 1 | 27
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating magnesiu... 1 | 10
increased circulating total pr... 1 | 28
increased erythrocyte cell num... 1 | 39
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
persistence of hyaloid vascula... 1 | 33
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

psoriasis 38 | 6,694
interstitial cystitis 33 | 2,312
lung cancer 33 | 4,740
Cancer 30 | 2,499
ovarian cancer 30 | 8,520
lung carcinoma 28 | 2,843
ulcerative colitis 28 | 1,819
tuberculosis 26 | 2,010
non-small cell lung cancer 24 | 2,890
glioblastoma 23 | 5,792
osteosarcoma 23 | 7,950
Carcinoma 22 | 11,493
Asthma 21 | 385
cutaneous lupus erythematosus 21 | 1,057
invasive ductal carcinoma 20 | 2,951
malignant mesothelioma 20 | 3,232
lung adenocarcinoma 19 | 2,716
Breast cancer 18 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
Astrocytoma, Pilocytic 17 | 3,081
adult high grade glioma 17 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
medulloblastoma, large-cell 17 | 6,241
ependymoma 15 | 4,679
pancreatic cancer 15 | 2,398
Hypersensitivity 14 | 63
Pneumonia 14 | 174
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
Arthritis 13 | 290
Liver Cirrhosis, Experimental 13 | 769
atypical teratoid / rhabdoid tumor 13 | 5,112
cystic fibrosis 13 | 1,696
Allergic hypersensitivity disease 12 | 126
Multiple Sclerosis 12 | 540
colon cancer 12 | 1,478
diabetes mellitus 12 | 1,728
subependymal giant cell astrocytoma 12 | 2,287
Atherosclerosis 11 | 291
Atopic dermatitis 11 | 952
Hypereosinophilic syndrome 11 | 71
Dermatitis 10 | 157
Inflammatory bowel disease 10 | 151
Influenza 10 | 142
Lung disease 10 | 142
Rheumatoid arthritis 10 | 1,191
group 3 medulloblastoma 10 | 4,104
Coronary artery disease 9 | 268
Glomerulonephritis 9 | 46
Schizophrenia 9 | 1,160
breast carcinoma 9 | 1,638
nasopharyngeal carcinoma 9 | 1,058
Bipolar Disorder 8 | 666
Dermatitis, Atopic 8 | 37
esophageal adenocarcinoma 8 | 737
head and neck cancer 8 | 271
mucosa-associated lymphoid tissue lymphoma 8 | 484
periodontitis 8 | 293
pituitary cancer 8 | 1,972
primary Sjogren syndrome 8 | 735
Allergic rhinitis 7 | 95
Human immunodeficiency virus infectious disease 7 | 138
Hypersensitivity reaction type II disease 7 | 253
Hypertension 7 | 396
Inflammation 7 | 120
Kidney disease 7 | 430
Malaria 7 | 160
Mesothelioma, Malignant 7 | 105
Pulmonary Fibrosis 7 | 106
Vascular disease 7 | 319
active Crohn's disease 7 | 922
adrenocortical carcinoma 7 | 1,428
chronic lymphosyte leukemia 7 | 204
head and neck cancer and chronic obstructive pulmonary disease 7 | 239
hepatocellular carcinoma 7 | 547
Arsenic Poisoning 6 | 62
Common cold 6 | 69
Heart disease 6 | 306
Kidney cancer 6 | 2,613
Meningitis 6 | 67
Myocardial Ischemia 6 | 169
Waldenstrons macroglobulinemia 6 | 765
active ulcerative colitis 6 | 764
dermatomyositis 6 | 966
gastric carcinoma 6 | 807
sarcoidosis 6 | 370
Arthritis, Rheumatoid 5 | 174
Brain Ischemia 5 | 110
Cerebrovascular disease 5 | 238
Crohn's disease 5 | 321
Dermatologic disorders 5 | 93
Endometriosis 5 | 540
Hypertensive disease 5 | 292
Melanoma 5 | 711
Mental Depression 5 | 333
Obesity 5 | 678
Peritonitis 5 | 43
Prostatic Neoplasms 5 | 495
aldosterone-producing adenoma 5 | 665
gastric cancer 5 | 459
spina bifida 5 | 1,074

Tissue

Blood and immune system 61 | 16,909
Digestive Tract 61 | 17,369
Endocrine System 61 | 18,159
Female tissues 61 | 17,400
Liver and Pancreas 61 | 16,750
Respiratory system 61 | 16,393
Male tissues 60 | 17,142
Skin and soft tissues 60 | 17,230
Urinary Tract 59 | 16,678
Nervous System 55 | 16,725
Cardiovascular System 51 | 15,192

Target Family

Non-IDG 52 | 12,091
Kinase 4 | 634
Enzyme 3 | 4,145
GPCR 2 | 408

GO Process

neutrophil chemotaxis 61 | 61
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosine-protein kinase SYK SYK Tchem Kinase -3.14835 1437.4 1136
Integrin alpha-9 ITGA9 Tbio Non-IDG -1.46619 29.0 124
Guanine nucleotide exchange factor VAV3 VAV3 Tbio Non-IDG -1.82116 74.0 249
Proto-oncogene vav VAV1 Tchem Non-IDG -2.66356 489.1 548
Junctional adhesion molecule-like JAML Tbio Non-IDG -1.66747 47.0 202
Interleukin-1 beta IL1B Tclin Non-IDG -4.40738 24522.4 1588
Galectin-3 LGALS3 Tchem Non-IDG -3.36655 2447.4 1101
Interferon gamma IFNG Tbio Non-IDG -3.90985 5727.4 2248
C-C motif chemokine 25 CCL25 Tbio Non-IDG -1.79784 59.1 303
C-C motif chemokine 5 CCL5 Tchem Non-IDG -3.39732 2431.2 660