Development Level

Tbio 32 | 11,445
Tchem 11 | 1,598
Tclin 3 | 613
Tdark 2 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

increased circulating chloride... 3 | 41
preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
abnormal gait 2 | 69
convulsive seizures 2 | 13
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
increased circulating sodium l... 2 | 71
increased total body fat amoun... 2 | 134
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal hair growth 1 | 10
abnormal locomotor behavior 1 | 24
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal testis morphology 1 | 43
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased heart left ventricle... 1 | 28
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased pulmonary respirator... 1 | 5
decreased total body fat amoun... 1 | 207
enlarged stomach 1 | 2
head bobbing 1 | 5
hemorrhage 1 | 23
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
short tibia 1 | 97
small testis 1 | 58
small thymus 1 | 16
thin ventricular wall 1 | 24
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Carcinoma 35 | 11,493
adult high grade glioma 30 | 3,801
ependymoma 30 | 4,679
glioblastoma 30 | 5,792
atypical teratoid / rhabdoid tumor 28 | 5,112
medulloblastoma, large-cell 28 | 6,241
Astrocytoma, Pilocytic 25 | 3,081
group 3 medulloblastoma 24 | 4,104
oligodendroglioma 22 | 2,850
astrocytic glioma 20 | 2,597
primitive neuroectodermal tumor 20 | 3,035
psoriasis 20 | 6,694
Schizophrenia 19 | 1,160
ovarian cancer 19 | 8,520
osteosarcoma 17 | 7,950
lung carcinoma 15 | 2,843
subependymal giant cell astrocytoma 15 | 2,287
Pick disease 14 | 1,894
lung cancer 13 | 4,740
malignant mesothelioma 13 | 3,232
Kidney cancer 12 | 2,613
Bipolar Disorder 11 | 666
Epilepsy 9 | 792
Parkinson's disease 9 | 392
pituitary cancer 9 | 1,972
Alzheimer's disease 8 | 658
Breast cancer 8 | 3,578
Depressive disorder 8 | 409
non-small cell lung cancer 8 | 2,890
Cognitive delay 7 | 608
Global developmental delay 7 | 608
Intellectual disability 7 | 1,016
Mental Depression 7 | 333
Mental and motor retardation 7 | 608
Seizures 7 | 596
Autistic Disorder 6 | 364
astrocytoma 6 | 1,146
colon cancer 6 | 1,478
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
Cancer 5 | 2,499
cystic fibrosis 5 | 1,696
group 4 medulloblastoma 5 | 1,855
invasive ductal carcinoma 5 | 2,951
nasopharyngeal carcinoma 5 | 1,058
Alcoholic Intoxication, Chronic 4 | 289
Attention deficit hyperactivity disorder 4 | 278
Autosomal recessive predisposition 4 | 1,442
Blepharoptosis 4 | 231
Broad flat nasal bridge 4 | 236
Congenital Myasthenic Syndromes, Presynaptic 4 | 8
Congenital myasthenic syndrome 4 | 25
Hypoplastic mandible condyle 4 | 275
Liver cancer 4 | 604
Major Depressive Disorder 4 | 301
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Nasal bridge wide 4 | 236
Obesity 4 | 678
Strabismus 4 | 270
lung adenocarcinoma 4 | 2,716
pancreatic cancer 4 | 2,398
tuberculosis 4 | 2,010
Acquired scoliosis 3 | 281
Amyotrophic lateral sclerosis 3 | 451
Autism Spectrum Disorders 3 | 75
Botulism 3 | 24
Brain disease 3 | 96
Cleft Palate 3 | 271
Congenital Epicanthus 3 | 177
Curvature of spine 3 | 282
Dementia 3 | 175
Dull intelligence 3 | 645
Huntington's disease 3 | 76
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Mood Disorders 3 | 184
Nerve Degeneration 3 | 121
Neurodegenerative disease 3 | 414
Neurodevelopmental Disorders 3 | 70
Orbital separation excessive 3 | 244
Poor school performance 3 | 645
Prenatal onset 3 | 139
Rheumatoid arthritis 3 | 1,191
Severe mental retardation (I.Q. 20-34) 3 | 99
Short stature 3 | 531
Small head 3 | 374
Tetanus 3 | 68
Toxic encephalopathy 3 | 141
Unipolar Depression 3 | 250
Vascular disease 3 | 319
active ulcerative colitis 3 | 764
adrenocortical carcinoma 3 | 1,428
diabetes mellitus 3 | 1,728
medulloblastoma 3 | 720
non primary Sjogren syndrome sicca 3 | 891
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962

Tissue

Endocrine System 46 | 18,159
Nervous System 46 | 16,725
Skin and soft tissues 46 | 17,230
Digestive Tract 45 | 17,369
Female tissues 44 | 17,400
Liver and Pancreas 44 | 16,750
Male tissues 44 | 17,142
Urinary Tract 41 | 16,678
Blood and immune system 40 | 16,909
Respiratory system 39 | 16,393
Cardiovascular System 35 | 15,192

Target Family

Non-IDG 31 | 12,091
Enzyme 7 | 4,145
Transporter 5 | 473
GPCR 2 | 408
Kinase 2 | 634
Ion Channel 1 | 344

GO Process

neurotransmitter secretion 48 | 48
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Peripheral plasma membrane protein CASK CASK Tchem Kinase -2.12241 130.2 227
Heat shock cognate 71 kDa protein HSPA8 Tchem Non-IDG -2.95379 881.0 741
Glutamate decarboxylase 1 GAD1 Tbio Enzyme -2.96960 896.3 529
Synaptosomal-associated protein 25 SNAP25 Tbio Non-IDG -2.61491 385.0 821
Synaptotagmin-1 SYT1 Tbio Non-IDG -2.66042 455.0 616
Syntaxin-binding protein 1 STXBP1 Tbio Non-IDG -2.30714 221.0 351
Liprin-alpha-1 PPFIA1 Tbio Non-IDG -1.63222 44.0 131
Segment polarity protein dishevelled homolog DVL-1 DVL1 Tchem Non-IDG -2.11561 188.4 169
Receptor-type tyrosine-protein phosphatase N2 PTPRN2 Tbio Enzyme -2.46190 287.4 307
Synaptic vesicular amine transporter SLC18A2 Tclin Transporter -2.98620 970.1 251