Development Level

Tbio 20 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

decreased bone mineral density 3 | 126
decreased body weight 2 | 161
decreased total body fat amoun... 2 | 207
preweaning lethality, complete... 2 | 979
thrombocytopenia 2 | 56
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal eating behavior 1 | 1
abnormal eye pigmentation 1 | 3
abnormal forced expiratory flo... 1 | 1
abnormal lung morphology 1 | 26
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal vertebrae morphology 1 | 18
abnormal whole-body plethysmog... 1 | 4
absent pinna reflex 1 | 23
altered righting response 1 | 1
corneal opacity 1 | 32
corneal vascularization 1 | 6
decreased body length 1 | 101
decreased body temperature 1 | 2
decreased bone mineral content 1 | 151
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased tidal volume 1 | 1
female infertility 1 | 60
hyperactivity 1 | 148
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased grip strength 1 | 41
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
male infertility 1 | 123
short tibia 1 | 97

Disease

Carcinoma 19 | 11,493
medulloblastoma, large-cell 16 | 6,241
Cancer 13 | 2,499
ovarian cancer 13 | 8,520
psoriasis 13 | 6,694
ependymoma 12 | 4,679
osteosarcoma 12 | 7,950
atypical teratoid / rhabdoid tumor 11 | 5,112
glioblastoma 11 | 5,792
group 3 medulloblastoma 11 | 4,104
lung cancer 11 | 4,740
oligodendroglioma 9 | 2,850
primitive neuroectodermal tumor 9 | 3,035
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
Astrocytoma, Pilocytic 7 | 3,081
Kidney cancer 7 | 2,613
astrocytic glioma 7 | 2,597
Breast cancer 6 | 3,578
adult high grade glioma 6 | 3,801
invasive ductal carcinoma 6 | 2,951
lung adenocarcinoma 6 | 2,716
lung carcinoma 6 | 2,843
malignant mesothelioma 6 | 3,232
Breast Neoplasms 5 | 445
Strabismus 5 | 270
acute quadriplegic myopathy 5 | 1,158
adrenocortical carcinoma 5 | 1,428
gastric carcinoma 5 | 807
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
non-small cell lung cancer 5 | 2,890
pediatric high grade glioma 5 | 1,064
Abnormally small eyeball 4 | 97
Adenoid Cystic Carcinoma 4 | 99
Autosomal recessive predisposition 4 | 1,442
Carcinoma, Adenoid Cystic 4 | 99
Cryptorchidism 4 | 296
Deafness 4 | 198
Decreased size of eyeball 4 | 97
Intellectual disability 4 | 1,016
Mammary Neoplasms 4 | 425
Microphthalmos 4 | 100
aldosterone-producing adenoma 4 | 665
astrocytoma 4 | 1,146
breast carcinoma 4 | 1,638
ductal carcinoma in situ 4 | 1,745
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
pancreatic cancer 4 | 2,398
pituitary cancer 4 | 1,972
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis 4 | 2,010
Anemia 3 | 365
Bipolar Disorder 3 | 666
Brain Neoplasms 3 | 33
Carcinoma, Pancreatic Ductal 3 | 20
Cognitive delay 3 | 608
Congenital Heart Defects 3 | 58
Congenital deafness 3 | 185
Congenital heart disease 3 | 93
Endometriosis 3 | 540
Esophageal atresia 3 | 43
Esophageal atresia with or without tracheoesophageal fistula 3 | 21
Global developmental delay 3 | 608
Hearing Loss, Partial 3 | 185
Liver disease 3 | 237
Lung Neoplasms 3 | 232
Mental and motor retardation 3 | 608
Neoplasm Metastasis 3 | 168
Rheumatoid arthritis 3 | 1,191
Short stature 3 | 531
Small head 3 | 374
Tracheoesophageal Fistula 3 | 36
chronic rhinosinusitis 3 | 512
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
dermatomyositis 3 | 966
diabetes mellitus 3 | 1,728
esophageal atresia/tracheoesophageal fistula 3 | 22
hearing impairment 3 | 199
hereditary spastic paraplegia 3 | 318
juvenile dermatomyositis 3 | 1,187
primary pancreatic ductal adenocarcinoma 3 | 1,109
Acquired scoliosis 2 | 281
Adenocarcinoma of lung 2 | 142
Colonic Neoplasms 2 | 142
Hemoglobin low 2 | 124
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Liver Cirrhosis 2 | 181
Liver cancer 2 | 604
Low Birth Weights 2 | 69
Microcephaly 2 | 166
Multiple Sclerosis 2 | 540
Pancytopenia 2 | 45
Pediatric failure to thrive 2 | 365
Phenotypic variability 2 | 150
Specific learning disability 2 | 47
cystic fibrosis and chronic rhinosinusitis 2 | 214

Tissue

Blood and immune system 22 | 16,909
Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Respiratory system 22 | 16,393
Urinary Tract 22 | 16,678
Cardiovascular System 21 | 15,192
Male tissues 21 | 17,142
Nervous System 21 | 16,725
Skin and soft tissues 21 | 17,230

Target Family

Non-IDG 13 | 12,091
Transcription Factor 7 | 1,400
Enzyme 2 | 4,145

GO Process

neuronal stem cell population ... 22 | 22
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paired mesoderm homeobox protein 1 PRRX1 Tbio Transcription Factor -1.58479 38.8 304
Matrix metalloproteinase-24 MMP24 Tbio Enzyme -1.38282 25.8 147
Alpha-(1,3)-fucosyltransferase 10 FUT10 Tdark Enzyme -0.25307 1.95 121
Forkhead box protein O1 FOXO1 Tbio Transcription Factor -3.05358 1143.3 1478
Forkhead box protein O3 FOXO3 Tbio Transcription Factor -2.94477 863.9 864
Fanconi anemia group C protein FANCC Tbio Non-IDG -2.85516 703.4 348
Transcription factor HES-5 HES5 Tbio Transcription Factor -2.08501 97.6 139
Abnormal spindle-like microcephaly-associated protein ASPM Tbio Non-IDG -1.52453 32.7 40
Insulin-like growth factor 2 mRNA-binding protein 1 IGF2BP1 Tbio Non-IDG -1.85997 76.0 207
Fanconi anemia group D2 protein FANCD2 Tbio Non-IDG -2.59123 391.6 404