Development Level

Tbio 79 | 11,445
Tchem 16 | 1,598
Tdark 7 | 6,588
Tclin 3 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 11 | 979
abnormal behavior 4 | 298
abnormal bone structure 4 | 187
short tibia 4 | 97
abnormal embryo size 3 | 220
decreased circulating creatini... 3 | 39
embryonic lethality prior to o... 3 | 239
preweaning lethality, incomple... 3 | 499
abnormal spleen morphology 2 | 55
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating choleste... 2 | 93
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
decreased lymphocyte cell numb... 2 | 83
decreased startle reflex 2 | 75
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
edema 2 | 59
embryonic lethality prior to t... 2 | 278
hemorrhage 2 | 23
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
increased anti-nuclear antigen... 2 | 19
increased blood urea nitrogen ... 2 | 48
increased circulating chloride... 2 | 41
increased circulating creatini... 2 | 38
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased or absent threshold ... 2 | 101
prenatal lethality prior to he... 2 | 87
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal embryo turning 1 | 31
abnormal gait 1 | 69
abnormal iris pigmentation 1 | 4
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal maxilla morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal sensory capabilities-... 1 | 8
abnormal skin coloration 1 | 25
cataract 1 | 92
convulsive seizures 1 | 13
decreased KLRG1+ CD4 alpha bet... 1 | 5
decreased blood urea nitrogen ... 1 | 51
decreased cardiac muscle contr... 1 | 11
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating fructosa... 1 | 30
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased pulmonary respirator... 1 | 5
decreased respiratory quotient 1 | 16
embryonic growth retardation 1 | 106
enlarged spleen 1 | 41
enlarged stomach 1 | 2
enlarged urinary bladder 1 | 8
hyperactivity 1 | 148
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased body length 1 | 32
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
pale liver 1 | 6
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
premature death 1 | 5
prenatal lethality 1 | 28
prolonged ST segment 1 | 36
small epididymis 1 | 3
small superior vagus ganglion 1 | 74
small testis 1 | 58
small thymus 1 | 16
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

Carcinoma 66 | 11,493
medulloblastoma, large-cell 61 | 6,241
ovarian cancer 59 | 8,520
osteosarcoma 56 | 7,950
glioblastoma 53 | 5,792
psoriasis 50 | 6,694
atypical teratoid / rhabdoid tumor 49 | 5,112
ependymoma 49 | 4,679
adult high grade glioma 47 | 3,801
Astrocytoma, Pilocytic 36 | 3,081
lung cancer 35 | 4,740
Breast cancer 34 | 3,578
group 3 medulloblastoma 33 | 4,104
oligodendroglioma 31 | 2,850
astrocytic glioma 27 | 2,597
lung carcinoma 27 | 2,843
Kidney cancer 25 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
malignant mesothelioma 25 | 3,232
Cancer 24 | 2,499
subependymal giant cell astrocytoma 24 | 2,287
Pick disease 23 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,955
non-small cell lung cancer 23 | 2,890
pituitary cancer 22 | 1,972
primitive neuroectodermal tumor 22 | 3,035
Schizophrenia 21 | 1,160
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
group 4 medulloblastoma 19 | 1,855
lung adenocarcinoma 19 | 2,716
Bipolar Disorder 18 | 666
colon cancer 17 | 1,478
invasive ductal carcinoma 17 | 2,951
Epilepsy 14 | 792
interstitial cystitis 14 | 2,312
pancreatic cancer 14 | 2,398
ulcerative colitis 14 | 1,819
Depressive disorder 13 | 409
Rheumatoid arthritis 13 | 1,191
pediatric high grade glioma 13 | 1,064
Alzheimer's disease 12 | 658
Parkinson's disease 12 | 392
breast carcinoma 12 | 1,638
tuberculosis 12 | 2,010
Intellectual disability 11 | 1,016
diabetes mellitus 11 | 1,728
ductal carcinoma in situ 11 | 1,745
spina bifida 11 | 1,074
Mental Depression 10 | 333
aldosterone-producing adenoma 10 | 665
cystic fibrosis 10 | 1,696
Alcoholic Intoxication, Chronic 9 | 289
Multiple myeloma 9 | 1,332
Seizures 9 | 596
Vascular disease 9 | 319
dermatomyositis 9 | 966
Amyotrophic lateral sclerosis 8 | 451
Brain disease 8 | 96
Liver cancer 8 | 604
Major Depressive Disorder 8 | 301
Neurodegenerative disease 8 | 414
astrocytoma 8 | 1,146
esophageal adenocarcinoma 8 | 737
gastric carcinoma 8 | 807
juvenile dermatomyositis 8 | 1,187
medulloblastoma 8 | 720
nasopharyngeal carcinoma 8 | 1,058
Dementia 7 | 175
Toxic encephalopathy 7 | 141
Unipolar Depression 7 | 250
acute quadriplegic myopathy 7 | 1,158
adrenocortical carcinoma 7 | 1,428
fibroadenoma 7 | 559
non primary Sjogren syndrome sicca 7 | 891
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
progressive supranuclear palsy 7 | 676
Autistic Disorder 6 | 364
Cerebrovascular disease 6 | 238
Chronic Lymphocytic Leukemia 6 | 262
Down syndrome 6 | 499
Dull intelligence 6 | 645
Hermansky-Pudlak syndrome 6 | 42
Liver Cirrhosis, Experimental 6 | 769
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Platelet storage pool deficiency 6 | 21
Poor school performance 6 | 645
acute myeloid leukemia 6 | 783
primary pancreatic ductal adenocarcinoma 6 | 1,109
Autosomal recessive predisposition 5 | 1,442
Breast Neoplasms 5 | 445
Endometriosis 5 | 540
Hypertension 5 | 396
Mammary Neoplasms 5 | 425
Prostatic Neoplasms 5 | 495
Pulmonary Fibrosis 5 | 106
Waldenstrons macroglobulinemia 5 | 765
cutaneous lupus erythematosus 5 | 1,057
hereditary spastic paraplegia 5 | 318

Tissue

Endocrine System 104 | 18,159
Blood and immune system 103 | 16,909
Digestive Tract 103 | 17,369
Female tissues 102 | 17,400
Liver and Pancreas 102 | 16,750
Male tissues 102 | 17,142
Nervous System 102 | 16,725
Skin and soft tissues 102 | 17,230
Urinary Tract 100 | 16,678
Respiratory system 99 | 16,393
Cardiovascular System 95 | 15,192

Target Family

Non-IDG 74 | 12,091
Enzyme 14 | 4,145
Kinase 9 | 634
Transcription Factor 3 | 1,400
Epigenetic 2 | 242
GPCR 2 | 408
TF/Epigenetic 1 | 38

GO Process

neuron projection development 105 | 105
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Leucine-rich glioma-inactivated protein 1 LGI1 Tbio Non-IDG -2.52790 342.7 207
Myocilin MYOC Tbio Non-IDG -2.65916 482.8 169
EF-hand domain-containing protein D1 EFHD1 Tbio Non-IDG -1.96673 92.2 187
Rap guanine nucleotide exchange factor 2 RAPGEF2 Tbio Non-IDG -1.41107 29.0 79
Protein BTG2 BTG2 Tbio Non-IDG -2.10376 142.7 209
Neurturin NRTN Tbio Non-IDG -2.21792 170.4 331
Hepatoma-derived growth factor-related protein 3 HDGFL3 Tbio Epigenetic -0.42051 3.29 139
Biogenesis of lysosome-related organelles complex 1 subunit 4 BLOC1S4 Tdark Non-IDG 0.00000 53
Contactin-associated protein-like 2 CNTNAP2 Tbio Non-IDG -2.36156 228.4 191
Biogenesis of lysosome-related organelles complex 1 subunit 2 BLOC1S2 Tbio Non-IDG -2.89123 759.6 79