Development Level

Tbio 14 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal eating behavior 1 | 1
abnormal forced expiratory flo... 1 | 1
abnormal whole-body plethysmog... 1 | 4
altered righting response 1 | 1
decreased body temperature 1 | 2
decreased body weight 1 | 161
decreased circulating glycerol... 1 | 16
decreased tidal volume 1 | 1
increased blood urea nitrogen ... 1 | 48
increased circulating iron lev... 1 | 30
increased fluid intake 1 | 1
increased grip strength 1 | 41
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 10 | 11,493
medulloblastoma, large-cell 9 | 6,241
adult high grade glioma 7 | 3,801
oligodendroglioma 7 | 2,850
psoriasis 7 | 6,694
ovarian cancer 6 | 8,520
Astrocytoma, Pilocytic 5 | 3,081
Cancer 5 | 2,499
atypical teratoid / rhabdoid tumor 5 | 5,112
ependymoma 5 | 4,679
glioblastoma 5 | 5,792
lung cancer 5 | 4,740
lung carcinoma 5 | 2,843
pituitary cancer 5 | 1,972
Breast cancer 4 | 3,578
astrocytic glioma 4 | 2,597
group 3 medulloblastoma 4 | 4,104
malignant mesothelioma 4 | 3,232
osteosarcoma 4 | 7,950
primitive neuroectodermal tumor 4 | 3,035
Dull intelligence 3 | 645
Intellectual disability 3 | 1,016
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Poor school performance 3 | 645
Vesico-Ureteral Reflux 3 | 33
breast carcinoma 3 | 1,638
diabetes mellitus 3 | 1,728
group 4 medulloblastoma 3 | 1,855
interstitial cystitis 3 | 2,312
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
Abnormality of the cerebrum 2 | 3
Absent auditory canals 2 | 23
Absent external auditory canals 2 | 23
Atresia of the external auditory canal 2 | 23
Atretic auditory canal 2 | 23
Bipolar Disorder 2 | 666
Branchioma 2 | 3
Branchiootic syndrome 2 | 12
Branchiootorenal syndrome 2 | 8
Breast Neoplasms 2 | 445
Byzanthine arch palate 2 | 194
Cholesteatoma 2 | 16
Cleft uvula 2 | 27
Conductive hearing loss 2 | 123
Congenital Abnormalities 2 | 11
Congenital Abnormality 2 | 11
Congenital central hypoventilation syndrome 2 | 18
Congenital deafness 2 | 185
Craniofacial Abnormalities 2 | 151
Deafness 2 | 198
Decreased size of teeth 2 | 62
Decreased width of tooth 2 | 59
Deep overbite 2 | 4
Euthyroid Goiter 2 | 3
Glaucoma 2 | 239
Hearing Loss, Mixed Conductive-Sensorineural 2 | 12
Hearing Loss, Partial 2 | 185
Highly variable severity 2 | 157
Hip Dislocation, Congenital 2 | 48
Hypoplastic cochlea 2 | 6
Incomplete partition of the cochlea type II 2 | 3
Kidney cancer 2 | 2,613
Major Depressive Disorder 2 | 301
Malformed ossicles 2 | 3
Malformed pinnae 2 | 37
Mammary Neoplasms 2 | 425
Mental and motor retardation 2 | 608
Microdontia (disorder) 2 | 59
Middle ear malformations 2 | 5
Mondini malformation 2 | 3
Mood Disorders 2 | 184
Narrow face 2 | 54
Narrowing of ear canal 2 | 13
Nonsyndromic deafness 2 | 142
Overbite 2 | 4
Pick disease 2 | 1,894
Posterior lingual occlusion of mandibular teeth 2 | 4
Preauricular Fistulae, Congenital 2 | 27
Preauricular dimple 2 | 27
Preauricular sinus 2 | 27
Preauricular skin tag 2 | 19
RENAL ADYSPLASIA 2 | 25
Renal agenesis 2 | 29
Renal dysplasia 2 | 28
Renal hypoplasia/aplasia 2 | 7
Schizophrenia 2 | 1,160
Sensorineural Hearing Loss (disorder) 2 | 284
Stenosis of external auditory canal 2 | 13
Thin face 2 | 54
Townes-Brocks syndrome 2 | 15
Unipolar Depression 2 | 250
Variable expressivity 2 | 157
hearing impairment 2 | 199
non-small cell lung cancer 2 | 2,890
pediatric high grade glioma 2 | 1,064
sonic hedgehog group medulloblastoma 2 | 467
subependymal giant cell astrocytoma 2 | 2,287

Tissue

Endocrine System 14 | 18,159
Nervous System 13 | 16,725
Digestive Tract 12 | 17,369
Skin and soft tissues 11 | 17,230
Blood and immune system 10 | 16,909
Male tissues 10 | 17,142
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Urinary Tract 8 | 16,678
Respiratory system 7 | 16,393
Cardiovascular System 4 | 15,192

Target Family

Transcription Factor 12 | 1,400
Non-IDG 2 | 12,091
Kinase 1 | 634

GO Process

neuron fate specification 15 | 15
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myelin transcription factor 1-like protein MYT1L Tbio Transcription Factor -1.49407 30.1 40
Achaete-scute homolog 1 ASCL1 Tbio Transcription Factor -2.44791 277.6 405
POU domain, class 4, transcription factor 1 POU4F1 Tbio Transcription Factor -2.19846 154.8 107
Doublesex- and mab-3-related transcription factor A2 DMRTA2 Tbio Transcription Factor -1.06699 14.5 78
Insulin gene enhancer protein ISL-1 ISL1 Tbio Transcription Factor -2.63352 410.3 382
T-cell leukemia homeobox protein 3 TLX3 Tbio Transcription Factor -1.71132 52.4 122
GS homeobox 2 GSX2 Tbio Transcription Factor -1.56813 38.8 92
Hepatocyte nuclear factor 3-alpha FOXA1 Tbio Transcription Factor -2.41829 249.1 744
POU domain, class 3, transcription factor 2 POU3F2 Tbio Transcription Factor -2.09509 119.7 272
Homeobox protein Nkx-2.2 NKX2-2 Tbio Transcription Factor -2.06202 108.0 379