Development Level

Tbio 72 | 11,445
Tchem 18 | 1,598
Tclin 7 | 613
Tdark 3 | 6,588

Collection

Kinase: IDG Consortium (Comple... 3 | 37
GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, incomple... 7 | 499
preweaning lethality, complete... 6 | 979
abnormal heart morphology 3 | 162
decreased bone mineral content 3 | 151
decreased bone mineral density 3 | 126
decreased circulating HDL chol... 3 | 68
decreased vertical activity 3 | 208
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
enlarged heart 3 | 210
short tibia 3 | 97
abnormal liver morphology 2 | 17
decreased caudal vertebrae num... 2 | 53
decreased circulating serum al... 2 | 82
decreased circulating total pr... 2 | 49
decreased lean body mass 2 | 135
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
increased circulating HDL chol... 2 | 80
increased total body fat amoun... 2 | 134
small superior vagus ganglion 2 | 74
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal brain morphology 1 | 13
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal heart left ventricle ... 1 | 16
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal rib morphology 1 | 10
cataract 1 | 92
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating glycerol... 1 | 16
decreased circulating insulin ... 1 | 76
decreased total body fat amoun... 1 | 207
edema 1 | 59
female infertility 1 | 60
hydroencephaly 1 | 14
hydrometra 1 | 53
hydrops fetalis 1 | 1
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating insulin ... 1 | 3
increased fluid intake 1 | 1
increased grip strength 1 | 41
increased kidney weight 1 | 6
increased lean body mass 1 | 172
lordosis 1 | 1
microphthalmia 1 | 26
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small adrenal glands 1 | 16
small heart 1 | 10
small kidney 1 | 16
vertebral transformation 1 | 12

Disease

Carcinoma 68 | 11,493
ovarian cancer 44 | 8,520
glioblastoma 43 | 5,792
medulloblastoma, large-cell 43 | 6,241
psoriasis 43 | 6,694
ependymoma 41 | 4,679
atypical teratoid / rhabdoid tumor 40 | 5,112
lung cancer 38 | 4,740
osteosarcoma 38 | 7,950
Cancer 32 | 2,499
group 3 medulloblastoma 30 | 4,104
oligodendroglioma 27 | 2,850
adult high grade glioma 25 | 3,801
Breast cancer 24 | 3,578
Kidney cancer 23 | 2,613
malignant mesothelioma 23 | 3,232
primitive neuroectodermal tumor 23 | 3,035
astrocytic glioma 22 | 2,597
Astrocytoma, Pilocytic 20 | 3,081
interstitial cystitis 19 | 2,312
lung carcinoma 19 | 2,843
non-small cell lung cancer 19 | 2,890
lung adenocarcinoma 18 | 2,716
pituitary cancer 18 | 1,972
colon cancer 17 | 1,478
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
invasive ductal carcinoma 17 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
group 4 medulloblastoma 15 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
subependymal giant cell astrocytoma 15 | 2,287
Pick disease 14 | 1,894
Intellectual disability 13 | 1,016
Schizophrenia 13 | 1,160
cystic fibrosis 13 | 1,696
ductal carcinoma in situ 13 | 1,745
pancreatic cancer 13 | 2,398
tuberculosis 13 | 2,010
astrocytoma 11 | 1,146
pediatric high grade glioma 11 | 1,064
ulcerative colitis 11 | 1,819
breast carcinoma 10 | 1,638
active Crohn's disease 9 | 922
cutaneous lupus erythematosus 9 | 1,057
Dull intelligence 8 | 645
Epilepsy 8 | 792
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Obesity 8 | 678
Parkinson's disease 8 | 392
Poor school performance 8 | 645
Rheumatoid arthritis 8 | 1,191
active ulcerative colitis 8 | 764
acute myeloid leukemia 8 | 783
diabetes mellitus 8 | 1,728
Atopic dermatitis 7 | 952
Cognitive delay 7 | 608
Down syndrome 7 | 499
Global developmental delay 7 | 608
Mental and motor retardation 7 | 608
Multiple myeloma 7 | 1,332
Osteoporosis 7 | 363
non primary Sjogren syndrome sicca 7 | 891
spina bifida 7 | 1,074
Acquired scoliosis 6 | 281
Alzheimer's disease 6 | 658
Autistic Disorder 6 | 364
Autosomal recessive predisposition 6 | 1,442
Bipolar Disorder 6 | 666
Cleft Palate 6 | 271
Concave bridge of nose 6 | 195
Cryptorchidism 6 | 296
Curvature of spine 6 | 282
Depressed nasal bridge 6 | 195
Depressed nasal root/bridge 6 | 195
Hypoplastic mandible condyle 6 | 275
Kidney disease 6 | 430
Mandibular hypoplasia 6 | 275
Micrognathism 6 | 275
Orbital separation excessive 6 | 244
Seizures 6 | 596
Unipolar Depression 6 | 250
Vascular disease 6 | 319
acute quadriplegic myopathy 6 | 1,158
atypical teratoid/rhabdoid tumor 6 | 357
chronic lymphosyte leukemia 6 | 204
fibroadenoma 6 | 559
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Low set ears 5 | 181
Muscle hypotonia 5 | 571
Short nose 5 | 132
Short stature 5 | 531
Small nose 5 | 132
Strabismus 5 | 270
Type 2 diabetes mellitus 5 | 272
adrenocortical carcinoma 5 | 1,428
esophageal adenocarcinoma 5 | 737
medulloblastoma 5 | 720
primary pancreatic ductal adenocarcinoma 5 | 1,109

Tissue

Endocrine System 97 | 18,159
Female tissues 95 | 17,400
Nervous System 94 | 16,725
Digestive Tract 91 | 17,369
Male tissues 91 | 17,142
Skin and soft tissues 91 | 17,230
Urinary Tract 90 | 16,678
Blood and immune system 87 | 16,909
Respiratory system 86 | 16,393
Liver and Pancreas 85 | 16,750
Cardiovascular System 79 | 15,192

Target Family

Non-IDG 42 | 12,091
Transcription Factor 20 | 1,400
Kinase 12 | 634
Enzyme 11 | 4,145
GPCR 9 | 408
Epigenetic 3 | 242
Ion Channel 2 | 344
Transporter 1 | 473

GO Process

neuron differentiation 100 | 100
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone deacetylase 9 HDAC9 Tclin Epigenetic -2.27309 185.2 431
Protein BTG4 BTG4 Tbio Non-IDG -1.04941 12.0 112
Myelin transcription factor 1-like protein MYT1L Tbio Transcription Factor -1.49407 30.1 40
Protein Wnt-6 WNT6 Tbio Non-IDG -1.65830 46.6 186
Alpha-soluble NSF attachment protein NAPA Tbio Non-IDG -1.91664 86.4 148
DNA damage-inducible transcript 4 protein DDIT4 Tbio Non-IDG -2.11497 150.3 231
BarH-like 2 homeobox protein BARHL2 Tbio Transcription Factor -0.91713 9.51 53
Probable global transcription activator SNF2L1 SMARCA1 Tbio Non-IDG -2.20560 145.6 116
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.07197 862.4 2448
LIM domain-binding protein 1 LDB1 Tbio Non-IDG -2.22623 164.4 206