Development Level

Tbio 9 | 11,445
Tclin 8 | 613
Tchem 7 | 1,598
Tdark 1 | 6,588

Collection

Ion Channel: IDG Consortium (T... 3 | 99

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal behavioral response t... 1 | 66
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal facial morphology 1 | 17
abnormal hair growth 1 | 10
abnormal head shape 1 | 10
abnormal joint morphology 1 | 23
abnormal limb morphology 1 | 13
abnormal outer ear morphology 1 | 3
brachydactyly 1 | 19
cyanosis 1 | 7
decreased circulating glucose ... 1 | 126
decreased mean corpuscular hem... 1 | 31
enlarged heart 1 | 210
hemorrhage 1 | 23
hyperactivity 1 | 148
increased circulating chloride... 1 | 41
increased circulating glucose ... 1 | 24
increased circulating sodium l... 1 | 71
increased grip strength 1 | 41
increased hematocrit 1 | 46
preweaning lethality, incomple... 1 | 499
syndactyly 1 | 23
thrombocytosis 1 | 27

Disease

Carcinoma 21 | 11,493
psoriasis 14 | 6,694
Nicotine dependence 9 | 54
glioblastoma 9 | 5,792
medulloblastoma, large-cell 9 | 6,241
atypical teratoid / rhabdoid tumor 8 | 5,112
osteosarcoma 8 | 7,950
Astrocytoma, Pilocytic 7 | 3,081
adult high grade glioma 7 | 3,801
astrocytic glioma 7 | 2,597
ependymoma 7 | 4,679
ovarian cancer 7 | 8,520
Epilepsy 6 | 792
General anesthesia 6 | 53
Neuropathy 6 | 261
Pellagra 6 | 26
Schizophrenia 6 | 1,160
lung cancer 6 | 4,740
oligodendroglioma 6 | 2,850
primitive neuroectodermal tumor 6 | 3,035
Autosomal recessive predisposition 5 | 1,442
Blepharoptosis 5 | 231
Byzanthine arch palate 5 | 194
Congenital myasthenic syndrome 5 | 25
Frontal lobe epilepsy 5 | 10
Multiple pterygium syndrome 5 | 18
Muscle relaxation, function 5 | 8
Niacin deficiency 5 | 5
Nicotine Withdrawal Symptoms 5 | 5
Seizures 5 | 596
Skeletal Muscle Relaxation for Endotracheal Intubation 5 | 5
Skeletal Muscle Relaxation for Endotracheal Intubation in C-Section 5 | 5
Smoking cessation assistance 5 | 8
acute quadriplegic myopathy 5 | 1,158
lung carcinoma 5 | 2,843
Bell Palsy 4 | 58
Bipolar Disorder 4 | 666
Cleft Palate 4 | 271
Congenital Myasthenic Syndromes, Postsynaptic 4 | 11
Depressive disorder 4 | 409
Easy fatigability 4 | 18
Facial Paresis 4 | 59
Facial muscle weakness of muscles innervated by CN VII 4 | 58
Feeding difficulties 4 | 127
Mental Depression 4 | 333
Muscle hypotonia 4 | 571
Myasthenic Syndrome, Congenital, 1A, Slow-Channel 4 | 4
Myasthenic Syndromes, Congenital 4 | 16
Myasthenic syndrome, congenital, postsynaptic slow-channel 4 | 4
Neonatal Hypotonia 4 | 64
Ophthalmoplegia 4 | 106
TOBACCO ADDICTION, SUSCEPTIBILITY TO 4 | 12
TOBACCO ADDICTION, SUSCEPTIBILITY TO (finding) 4 | 12
Tires quickly 4 | 18
interstitial cystitis 4 | 2,312
lung adenocarcinoma 4 | 2,716
pituitary cancer 4 | 1,972
Abnormal behavior 3 | 52
Akinesia 3 | 13
Alcohol dependence 3 | 107
Alcoholic Intoxication, Chronic 3 | 289
Amyotrophic lateral sclerosis 3 | 451
Arthrogryposis 3 | 54
Breast cancer 3 | 3,578
Cancer 3 | 2,499
Congenital Epicanthus 3 | 177
Congenital anomaly of face 3 | 56
Contracture 3 | 96
Contracture of joint 3 | 93
Cystic lymphangioma 3 | 19
Deglutition Disorders 3 | 132
Distortion of face 3 | 46
Dysmorphic facies 3 | 46
Early severe fetal akinesia sequence 3 | 11
Flexion contracture 3 | 93
Flexion contractures of joints 3 | 93
Funny looking face 3 | 46
Fused vertebrae 3 | 25
Highly variable severity 3 | 157
Increased susceptibility to fractures 3 | 21
Infantile onset 3 | 238
Lymphangioma, Cystic 3 | 21
MULTIPLE PTERYGIUM SYNDROME, LETHAL TYPE 3 | 5
Neck muscle weakness 3 | 17
Neurogenic bladder 3 | 16
Pena-Shokeir syndrome type I 3 | 12
Polyhydramnios 3 | 108
Prenatal onset 3 | 139
Respiratory Insufficiency 3 | 132
Respiratory function loss 3 | 121
Thin rib 3 | 21
Variable expressivity 3 | 157
Vertebral body fusion 3 | 25
facial deformity 3 | 46
juvenile dermatomyositis 3 | 1,187
medulloblastoma 3 | 720
pediatric high grade glioma 3 | 1,064
pterygium 3 | 76
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010

Tissue

Endocrine System 24 | 18,159
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Digestive Tract 22 | 17,369
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Skin and soft tissues 22 | 17,230
Blood and immune system 20 | 16,909
Urinary Tract 19 | 16,678
Respiratory system 18 | 16,393
Cardiovascular System 15 | 15,192

Target Family

Ion Channel 13 | 344
Non-IDG 6 | 12,091
Enzyme 2 | 4,145
GPCR 1 | 408
Kinase 1 | 634
Transcription Factor 1 | 1,400
Transporter 1 | 473

GO Process

neuromuscular synaptic transmi... 25 | 25
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuronal acetylcholine receptor subunit beta-2 CHRNB2 Tclin Ion Channel -1.62448 37.6 174
Double-stranded RNA-specific editase 1 ADARB1 Tbio Enzyme -2.08959 118.0 103
Acetylcholine receptor subunit alpha CHRNA1 Tclin Ion Channel -1.66400 41.7 307
F-BAR and double SH3 domains protein 2 FCHSD2 Tbio Non-IDG -1.56117 35.3 75
F-BAR and double SH3 domains protein 1 FCHSD1 Tdark Non-IDG -0.23145 1.99 81
Muscarinic acetylcholine receptor M1 CHRM1 Tclin GPCR -2.16159 140.8 222
P2X purinoceptor 3 P2RX3 Tchem Ion Channel -2.55623 360.2 162
Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 Tchem Ion Channel -1.31722 18.3 117
Dystrobrevin alpha DTNA Tbio Non-IDG -2.25692 181.5 151
Acetylcholine receptor subunit delta CHRND Tclin Ion Channel -1.30154 18.9 155