Development Level

Tbio 28 | 11,445
Tchem 7 | 1,598
Tclin 4 | 613
Tdark 3 | 6,588

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

abnormal behavior 4 | 298
decreased grip strength 3 | 116
abnormal locomotor behavior 2 | 24
decreased body weight 2 | 161
decreased circulating HDL chol... 2 | 68
decreased total body fat amoun... 2 | 207
hyperactivity 2 | 148
hypoactivity 2 | 132
increased circulating chloride... 2 | 41
increased lean body mass 2 | 172
preweaning lethality, incomple... 2 | 499
tremors 2 | 39
abnormal bone structure 1 | 187
abnormal gait 1 | 69
abnormal locomotor activation 1 | 16
decreased basophil cell number 1 | 16
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased pulmonary respirator... 1 | 5
enlarged stomach 1 | 2
impaired glucose tolerance 1 | 75
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased mean corpuscular vol... 1 | 92
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
premature death 1 | 5
preweaning lethality, complete... 1 | 979
short tibia 1 | 97
small testis 1 | 58
small thymus 1 | 16
thrombocytosis 1 | 27

Disease

Carcinoma 27 | 11,493
glioblastoma 21 | 5,792
ovarian cancer 21 | 8,520
atypical teratoid / rhabdoid tumor 20 | 5,112
medulloblastoma, large-cell 20 | 6,241
osteosarcoma 18 | 7,950
ependymoma 17 | 4,679
group 3 medulloblastoma 17 | 4,104
Astrocytoma, Pilocytic 16 | 3,081
Kidney cancer 15 | 2,613
psoriasis 15 | 6,694
adult high grade glioma 13 | 3,801
oligodendroglioma 13 | 2,850
primitive neuroectodermal tumor 12 | 3,035
Breast cancer 11 | 3,578
Intellectual disability 11 | 1,016
Schizophrenia 11 | 1,160
subependymal giant cell astrocytoma 11 | 2,287
Autosomal recessive predisposition 10 | 1,442
Pick disease 10 | 1,894
Epilepsy 9 | 792
Neurodegenerative disease 8 | 414
lung cancer 8 | 4,740
malignant mesothelioma 8 | 3,232
tuberculosis 8 | 2,010
astrocytic glioma 7 | 2,597
pediatric high grade glioma 7 | 1,064
pituitary cancer 7 | 1,972
Bipolar Disorder 6 | 666
Cancer 6 | 2,499
Cognitive delay 6 | 608
Global developmental delay 6 | 608
Mental and motor retardation 6 | 608
Muscle hypotonia 6 | 571
Rheumatoid arthritis 6 | 1,191
Seizures 6 | 596
group 4 medulloblastoma 6 | 1,855
lung carcinoma 6 | 2,843
Alzheimer's disease 5 | 658
Autistic Disorder 5 | 364
Cerebral atrophy 5 | 178
Depressive disorder 5 | 409
Down syndrome 5 | 499
Dull intelligence 5 | 645
Liver cancer 5 | 604
Low intelligence 5 | 645
Major Depressive Disorder 5 | 301
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Poor school performance 5 | 645
Unipolar Depression 5 | 250
astrocytoma 5 | 1,146
cystic fibrosis 5 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
Absent reflex 4 | 92
Absent tendon reflex 4 | 92
Choreatic disease 4 | 52
Dementia 4 | 175
Dysarthria 4 | 192
Mental Depression 4 | 333
Reflex, Deep Tendon, Absent 4 | 92
Splenomegaly 4 | 190
Toxic encephalopathy 4 | 141
dermatomyositis 4 | 966
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
invasive ductal carcinoma 4 | 2,951
juvenile dermatomyositis 4 | 1,187
medulloblastoma 4 | 720
pancreatic cancer 4 | 2,398
ulcerative colitis 4 | 1,819
Autism spectrum disorder 3 | 101
Blind Vision 3 | 111
Blindness, Legal 3 | 110
Endometrial cancer 3 | 311
Fetal Growth Retardation 3 | 189
Fragile X syndrome 3 | 34
Highly variable severity 3 | 157
Infant, Small for Gestational Age 3 | 176
Intrauterine retardation 3 | 176
Multiple myeloma 3 | 1,332
Neurodevelopmental Disorders 3 | 70
Neuropathy 3 | 261
Parkinson's disease 3 | 392
Polycystic ovary syndrome 3 | 360
Precursor Cell Lymphoblastic Leukemia-Lymphoma 3 | 49
Prostatic Neoplasms 3 | 495
Short stature 3 | 531
Small head 3 | 374
Variable expressivity 3 | 157
Vascular disease 3 | 319
acute lymphocytic leukemia 3 | 33
adrenocortical carcinoma 3 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
colon cancer 3 | 1,478
diabetes mellitus 3 | 1,728
esophageal adenocarcinoma 3 | 737
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
primary Sjogren syndrome 3 | 735
primary pancreatic ductal adenocarcinoma 3 | 1,109

Tissue

Digestive Tract 39 | 17,369
Endocrine System 39 | 18,159
Skin and soft tissues 38 | 17,230
Female tissues 37 | 17,400
Liver and Pancreas 36 | 16,750
Male tissues 36 | 17,142
Nervous System 36 | 16,725
Blood and immune system 35 | 16,909
Urinary Tract 35 | 16,678
Respiratory system 34 | 16,393
Cardiovascular System 30 | 15,192

Target Family

Non-IDG 20 | 12,091
Enzyme 10 | 4,145
Transcription Factor 7 | 1,400
GPCR 1 | 408
Ion Channel 1 | 344
Kinase 1 | 634
Nuclear Receptor 1 | 48
Transporter 1 | 473

GO Process

neuromuscular process controll... 42 | 42
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Junctophilin-3 JPH3 Tbio Non-IDG -1.51901 34.8 165
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Biogenesis of lysosome-related organelles complex 1 subunit 4 BLOC1S4 Tdark Non-IDG 0.00000 53
Alanine--tRNA ligase, cytoplasmic AARS Tbio Enzyme -2.49617 295.2 140
POU domain, class 4, transcription factor 2 POU4F2 Tbio Transcription Factor -1.94397 90.2 145
Calmodulin-binding transcription activator 1 CAMTA1 Tbio Transcription Factor -1.48601 33.1 26
TRAF-interacting protein with FHA domain-containing protein B TIFAB Tbio Non-IDG -0.55328 2.93 54
Breakpoint cluster region protein BCR Tclin Non-IDG -2.99605 934.2 437
Neuroligin-2 NLGN2 Tbio Enzyme -1.71616 50.4 77
Immunoglobulin superfamily DCC subclass member 3 IGDCC3 Tdark Non-IDG -0.74905 5.49 28