Development Level

Tbio 20 | 11,445
Tchem 6 | 1,598
Tclin 3 | 613

Collection

Ion Channel: IDG Consortium (T... 5 | 99

IMPC Phenotype

impaired glucose tolerance 3 | 75
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal bone structure 1 | 187
abnormal joint morphology 1 | 23
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal rib morphology 1 | 10
abnormal testis morphology 1 | 43
brachydactyly 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased large unstained cell... 1 | 5
increased lymphocyte cell numb... 1 | 32
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
small testis 1 | 58
syndactyly 1 | 23

Disease

Carcinoma 27 | 11,493
ovarian cancer 17 | 8,520
medulloblastoma, large-cell 16 | 6,241
Kidney cancer 15 | 2,613
atypical teratoid / rhabdoid tumor 15 | 5,112
glioblastoma 15 | 5,792
Astrocytoma, Pilocytic 14 | 3,081
adult high grade glioma 14 | 3,801
lung cancer 14 | 4,740
ependymoma 13 | 4,679
psoriasis 12 | 6,694
group 3 medulloblastoma 11 | 4,104
lung carcinoma 10 | 2,843
malignant mesothelioma 10 | 3,232
oligodendroglioma 10 | 2,850
subependymal giant cell astrocytoma 10 | 2,287
Liver cancer 9 | 604
Pick disease 9 | 1,894
lung adenocarcinoma 9 | 2,716
osteosarcoma 9 | 7,950
primitive neuroectodermal tumor 9 | 3,035
ulcerative colitis 9 | 1,819
Breast cancer 8 | 3,578
astrocytic glioma 8 | 2,597
invasive ductal carcinoma 8 | 2,951
acute quadriplegic myopathy 7 | 1,158
ductal carcinoma in situ 7 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
pituitary cancer 7 | 1,972
Autosomal recessive predisposition 6 | 1,442
Bipolar Disorder 6 | 666
Endometrial cancer 6 | 311
Schizophrenia 6 | 1,160
breast carcinoma 6 | 1,638
interstitial cystitis 6 | 2,312
non-small cell lung cancer 6 | 2,890
Duchenne muscular dystrophy 5 | 601
Epilepsy 5 | 792
Intellectual disability 5 | 1,016
Melanoma 5 | 711
Skin cancer 5 | 469
astrocytoma 5 | 1,146
pancreatic cancer 5 | 2,398
Becker muscular dystrophy 4 | 191
Cancer 4 | 2,499
Major Depressive Disorder 4 | 301
Muscle Spasticity 4 | 195
active Crohn's disease 4 | 922
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
colon cancer 4 | 1,478
cystic fibrosis 4 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
juvenile dermatomyositis 4 | 1,187
nasopharyngeal carcinoma 4 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
spina bifida 4 | 1,074
Amyotrophic lateral sclerosis 3 | 451
Atopic dermatitis 3 | 952
Blepharoptosis 3 | 231
Cerebellar Ataxia 3 | 304
Down syndrome 3 | 499
Dull intelligence 3 | 645
Dysarthria 3 | 192
Highly variable severity 3 | 157
Hypoplastic mandible condyle 3 | 275
Infantile onset 3 | 238
Kidney disease 3 | 430
Low intelligence 3 | 645
Mandibular hypoplasia 3 | 275
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Micrognathism 3 | 275
Muscle hypotonia 3 | 571
Nephrotic Syndrome 3 | 78
Neurodegenerative disease 3 | 414
Neuropathy 3 | 261
Orbital separation excessive 3 | 244
Parkinson's disease 3 | 392
Poor school performance 3 | 645
Variable expressivity 3 | 157
cutaneous lupus erythematosus 3 | 1,057
group 4 medulloblastoma 3 | 1,855
pediatric high grade glioma 3 | 1,064
Acquired scoliosis 2 | 281
Cerebellar degeneration 2 | 103
Cerebrovascular disease 2 | 238
Curvature of spine 2 | 282
Long philtrum 2 | 137
Lung Neoplasms 2 | 232
Mood Disorders 2 | 184
Neuroblastoma 2 | 80
Paraplegia 2 | 74
Posteriorly rotated ear 2 | 61
Status Epilepticus 2 | 98
Strabismus 2 | 270
Toxic encephalopathy 2 | 141
Unipolar Depression 2 | 250
medulloblastoma 2 | 720
tuberculosis 2 | 2,010

Tissue

Blood and immune system 29 | 16,909
Digestive Tract 29 | 17,369
Endocrine System 29 | 18,159
Female tissues 28 | 17,400
Liver and Pancreas 28 | 16,750
Male tissues 28 | 17,142
Nervous System 28 | 16,725
Respiratory system 28 | 16,393
Skin and soft tissues 28 | 17,230
Urinary Tract 28 | 16,678
Cardiovascular System 26 | 15,192

Target Family

Non-IDG 12 | 12,091
Ion Channel 8 | 344
Kinase 5 | 634
Enzyme 4 | 4,145

GO Process

neuromuscular junction develop... 29 | 29
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 Tbio Ion Channel -1.46356 25.4 471
Acetylcholine receptor subunit alpha CHRNA1 Tclin Ion Channel -1.66400 41.7 307
Collagen alpha-1(IV) chain COL4A1 Tbio Non-IDG -2.28595 186.9 391
E3 ubiquitin-protein ligase PDZRN3 PDZRN3 Tbio Enzyme -1.20019 15.7 71
AFG3-like protein 2 AFG3L2 Tbio Enzyme -1.58716 39.9 164
Nardilysin NRDC Tbio Enzyme -1.70648 55.0 88
Protein unc-13 homolog A UNC13A Tbio Non-IDG -1.84052 68.3 23
Ankyrin-3 ANK3 Tbio Non-IDG -2.25280 172.9 170
Tenascin TNC Tbio Non-IDG -2.34421 216.5 642
E3 ubiquitin-protein ligase NEDD4 NEDD4 Tchem Enzyme -2.44046 259.8 167