Development Level

Tbio 5 | 11,445

IMPC Phenotype

abnormal bone structure 2 | 187
abnormal locomotor behavior 2 | 24
decreased circulating HDL chol... 2 | 68
decreased circulating alkaline... 2 | 46
decreased circulating choleste... 2 | 93
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
decreased lymphocyte cell numb... 2 | 83
decreased pulmonary respirator... 2 | 5
decreased total body fat amoun... 2 | 207
enlarged stomach 2 | 2
impaired glucose tolerance 2 | 75
increased circulating alkaline... 2 | 122
increased circulating amylase ... 2 | 25
increased circulating chloride... 2 | 41
increased lean body mass 2 | 172
increased red blood cell distr... 2 | 34
increased total body fat amoun... 2 | 134
short tibia 2 | 97
small thymus 2 | 16
tremors 2 | 39
decreased body weight 1 | 161
increased body weight 1 | 25
increased circulating triglyce... 1 | 42

Disease

Carcinoma 5 | 11,493
Kidney cancer 5 | 2,613
Bipolar Disorder 4 | 666
Liver cancer 4 | 604
Schizophrenia 4 | 1,160
atypical teratoid / rhabdoid tumor 4 | 5,112
psoriasis 4 | 6,694
Autism spectrum disorder 3 | 101
Autistic Disorder 3 | 364
Pitt-Hopkins syndrome 3 | 20
ependymoma 3 | 4,679
medulloblastoma, large-cell 3 | 6,241
ovarian cancer 3 | 8,520
subependymal giant cell astrocytoma 3 | 2,287
Alzheimer's disease 2 | 658
Asperger syndrome 2 | 37
Autism Spectrum Disorders 2 | 75
Breast cancer 2 | 3,578
Endometrial cancer 2 | 311
Epilepsy 2 | 792
Gilles de la Tourette syndrome 2 | 47
Intellectual disability 2 | 1,016
Large intestine cancer 2 | 126
Mental Depression 2 | 333
Motor neuron disease 2 | 49
Nicotine dependence 2 | 54
Obesity 2 | 678
Pitt-Hopkins-Like Syndrome 2 2 | 2
Rheumatoid arthritis 2 | 1,191
Systemic lupus erythematosus 2 | 194
Vascular disease 2 | 319
adult high grade glioma 2 | 3,801
colon cancer 2 | 1,478
glioblastoma 2 | 5,792
group 4 medulloblastoma 2 | 1,855
interstitial cystitis 2 | 2,312
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
oligodendroglioma 2 | 2,850
osteosarcoma 2 | 7,950
pituitary cancer 2 | 1,972
Acquired metabolic disease 1 | 336
Acquired scoliosis 1 | 281
Adenoid Cystic Carcinoma 1 | 99
Astrocytoma, Pilocytic 1 | 3,081
Atopic dermatitis 1 | 952
Breast Neoplasms 1 | 445
Cancer 1 | 2,499
Carcinoma, Adenoid Cystic 1 | 99
Cardiomyopathy 1 | 116
Cardiovascular system disease 1 | 246
Constipation 1 | 181
Cortical Dysplasia-Focal Epilepsy Syndrome 1 | 2
Craniofacial Abnormalities 1 | 151
Curvature of spine 1 | 282
Depressive disorder 1 | 409
Disease Models, Animal 1 | 155
Disease Progression 1 | 136
Drooling 1 | 27
Dyschezia 1 | 135
Epileptic encephalopathy 1 | 26
Gastroesophageal reflux disease 1 | 110
Gout 1 | 106
Heartburn 1 | 78
Hyperventilation 1 | 6
Kidney disease 1 | 430
Language Development Disorders 1 | 11
Liver disease 1 | 237
Lymphoid leukemia 1 | 160
MAJOR AFFECTIVE DISORDER 2 1 | 22
Melanoma 1 | 711
Myocardial Ischemia 1 | 169
Neoplasm Invasiveness 1 | 161
Neoplasm Metastasis 1 | 168
Nerve Degeneration 1 | 121
Osteoporosis 1 | 363
Pick disease 1 | 1,894
Protrusion of tongue 1 | 11
Severe mental retardation (I.Q. 20-34) 1 | 99
Sialorrhea 1 | 28
Skin cancer 1 | 469
Status Epilepticus 1 | 98
Stomach Neoplasms 1 | 300
Strabismus 1 | 270
active ulcerative colitis 1 | 764
acute myeloid leukemia 1 | 783
adrenocortical carcinoma 1 | 1,428
astrocytoma 1 | 1,146
breast carcinoma 1 | 1,638
chronic rhinosinusitis 1 | 512
ductal carcinoma in situ 1 | 1,745
gastric carcinoma 1 | 807
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
invasive ductal carcinoma 1 | 2,951
nasopharyngeal carcinoma 1 | 1,058
non-inflammatory breast cancer 1 | 66
pediatric high grade glioma 1 | 1,064
posterior fossa group B ependymoma 1 | 416
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Non-IDG 4 | 12,091
Enzyme 1 | 4,145

GO Process

neuroligin clustering involved... 5 | 5
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 MAGI2 Tbio Enzyme -1.54170 33.0 178
Cadherin-2 CDH2 Tbio Non-IDG -3.19431 1382.9 993
Neurexin-2 NRXN2 Tbio Non-IDG -0.88939 10.0 42
Neurexin-1-beta NRXN1 Tbio Non-IDG -1.88807 125.1 174