Development Level

Tbio 21 | 11,445
Tchem 5 | 1,598
Tdark 2 | 6,588
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal embryo size 2 | 220
abnormal QT variability 1 | 10
abnormal craniofacial morpholo... 1 | 33
abnormal forebrain morphology 1 | 10
abnormal forelimb morphology 1 | 2
abnormal hindbrain morphology 1 | 10
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal response to tactile s... 1 | 17
abnormal vertebrae morphology 1 | 18
cataract 1 | 92
decreased CD4-positive, alpha ... 1 | 7
decreased IgG1 level 1 | 8
decreased IgG2b level 1 | 4
decreased T cell number 1 | 15
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating total pr... 1 | 49
decreased lactate dehydrogenas... 1 | 16
decreased threshold for audito... 1 | 26
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
increased B cell number 1 | 9
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
syndactyly 1 | 23

Disease

Carcinoma 25 | 11,493
ovarian cancer 17 | 8,520
Kidney cancer 11 | 2,613
atypical teratoid / rhabdoid tumor 11 | 5,112
glioblastoma 11 | 5,792
lung cancer 11 | 4,740
osteosarcoma 10 | 7,950
psoriasis 10 | 6,694
adult high grade glioma 9 | 3,801
ependymoma 9 | 4,679
group 3 medulloblastoma 9 | 4,104
Breast cancer 8 | 3,578
Cancer 8 | 2,499
malignant mesothelioma 8 | 3,232
medulloblastoma, large-cell 8 | 6,241
oligodendroglioma 8 | 2,850
pancreatic cancer 8 | 2,398
astrocytic glioma 7 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
primitive neuroectodermal tumor 7 | 3,035
Astrocytoma, Pilocytic 6 | 3,081
Pick disease 6 | 1,894
invasive ductal carcinoma 6 | 2,951
lung carcinoma 6 | 2,843
spina bifida 6 | 1,074
Autosomal recessive predisposition 5 | 1,442
Dull intelligence 5 | 645
Intellectual disability 5 | 1,016
Liver cancer 5 | 604
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Poor school performance 5 | 645
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
pituitary cancer 5 | 1,972
Acquired scoliosis 4 | 281
Alzheimer's disease 4 | 658
Cognitive delay 4 | 608
Curvature of spine 4 | 282
Global developmental delay 4 | 608
Hypotrophic malar bone 4 | 129
Malar flattening 4 | 129
Mental and motor retardation 4 | 608
Schizophrenia 4 | 1,160
chronic rhinosinusitis 4 | 512
cystic fibrosis 4 | 1,696
ductal carcinoma in situ 4 | 1,745
interstitial cystitis 4 | 2,312
non-small cell lung cancer 4 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
sarcoidosis 4 | 370
subependymal giant cell astrocytoma 4 | 2,287
ulcerative colitis 4 | 1,819
Atopic dermatitis 3 | 952
Cataract 3 | 297
Decreased projection of midface 3 | 105
Exophthalmos 3 | 112
Heart disease 3 | 306
Hypotrophic midface 3 | 105
Kidney disease 3 | 430
Midface retrusion 3 | 105
Multiple Sclerosis 3 | 540
Myopia 3 | 176
Orbital separation excessive 3 | 244
Prenatal onset 3 | 139
Small head 3 | 374
Small midface 3 | 105
active Crohn's disease 3 | 922
aldosterone-producing adenoma 3 | 665
colon cancer 3 | 1,478
gastric carcinoma 3 | 807
lung adenocarcinoma 3 | 2,716
medulloblastoma 3 | 720
primary pancreatic ductal adenocarcinoma 3 | 1,109
progressive supranuclear palsy 3 | 676
Anteverted nostril 2 | 191
Broad flat nasal bridge 2 | 236
Cerebrovascular disease 2 | 238
Congenital Epicanthus 2 | 177
Endometrial cancer 2 | 311
Hypertension 2 | 396
Kidney Failure 2 | 111
Liver Cirrhosis 2 | 181
Liver Cirrhosis, Experimental 2 | 769
Long philtrum 2 | 137
Microcephaly 2 | 166
Nasal bridge wide 2 | 236
Neoplasm Invasiveness 2 | 161
Posteriorly rotated ear 2 | 61
Renal Insufficiency 2 | 90
Renal failure in adulthood 2 | 76
Severe mental retardation (I.Q. 20-34) 2 | 99
Short nose 2 | 132
Skin cancer 2 | 469
Small nose 2 | 132
Upward slant of palpebral fissure 2 | 75
active ulcerative colitis 2 | 764
posterior fossa group A ependymoma 2 | 468
tuberculosis and treatment for 6 months 2 | 409

Tissue

Blood and immune system 29 | 16,909
Endocrine System 29 | 18,159
Female tissues 29 | 17,400
Nervous System 29 | 16,725
Respiratory system 29 | 16,393
Urinary Tract 29 | 16,678
Digestive Tract 28 | 17,369
Liver and Pancreas 28 | 16,750
Male tissues 28 | 17,142
Skin and soft tissues 28 | 17,230
Cardiovascular System 27 | 15,192

Target Family

Non-IDG 16 | 12,091
Transcription Factor 6 | 1,400
Enzyme 3 | 4,145
Kinase 2 | 634
Epigenetic 1 | 242
Ion Channel 1 | 344

GO Process

neural tube development 29 | 29
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 358 ZNF358 Tdark Transcription Factor 0.02 1.33 96
Polycystin-2 PKD2 Tchem Ion Channel -2.63806 461.3 231
Cat eye syndrome critical region protein 2 CECR2 Tchem Epigenetic -2.17030 147.0 44
Transcription factor HES-5 HES5 Tbio Transcription Factor -2.08501 97.6 139
Dapper homolog 1 DACT1 Tbio Non-IDG -1.86707 79.6 106
Retinal dehydrogenase 2 ALDH1A2 Tbio Enzyme -2.25078 175.3 229
mRNA decay activator protein ZFP36L1 ZFP36L1 Tbio Non-IDG -1.51339 38.6 285
Polycystin-1 PKD1 Tbio Non-IDG -2.60276 379.9 123
Neurofibromin NF1 Tbio Non-IDG -3.60161 4054.2 355
Prospero homeobox protein 1 PROX1 Tbio Transcription Factor -2.31691 210.1 472