Development Level

Tbio 31 | 10,625
Tchem 6 | 1,890
Tclin 5 | 602
Tdark 3 | 7,003

IMPC Phenotype

preweaning lethality, complete... 5 | 633
decreased bone mineral content 2 | 157
decreased lean body mass 2 | 195
decreased rib number 2 | 59
embryonic lethality prior to t... 2 | 187
enlarged heart 2 | 111
impaired glucose tolerance 2 | 52
increased or absent threshold ... 2 | 128
limb grasping 2 | 35
abnormal QRS complex 1 | 25
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal embryo development 1 | 2
abnormal embryo turning 1 | 15
abnormal gait 1 | 51
abnormal nail morphology 1 | 7
abnormal pericardium morpholog... 1 | 11
cataract 1 | 26
decreased T cell number 1 | 31
decreased blood urea nitrogen ... 1 | 31
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased total body fat amoun... 1 | 186
enlarged spleen 1 | 26
hypoactivity 1 | 89
improved glucose tolerance 1 | 56
increased circulating alkaline... 1 | 119
increased circulating iron lev... 1 | 25
increased heart rate variabili... 1 | 4
increased total body fat amoun... 1 | 57
preweaning lethality, incomple... 1 | 260

Disease

psoriasis 25 | 6,685
medulloblastoma, large-cell 21 | 6,234
ovarian cancer 21 | 8,491
lung cancer 20 | 4,473
osteosarcoma 16 | 7,933
invasive ductal carcinoma 14 | 2,950
glioblastoma 13 | 5,572
group 3 medulloblastoma 13 | 2,254
malignant mesothelioma 13 | 3,163
breast carcinoma 12 | 1,614
Cancer 11 | 2,346
Carcinoma 11 | 2,147
cystic fibrosis 11 | 1,670
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,289
oligodendroglioma 11 | 2,849
ulcerative colitis 11 | 2,087
Breast cancer 10 | 3,098
lung adenocarcinoma 10 | 2,714
lung carcinoma 10 | 2,844
subependymal giant cell astrocytoma 10 | 2,287
Hirschsprung's disease 9 | 44
astrocytic glioma 9 | 2,241
atypical teratoid / rhabdoid tumor 9 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
colon cancer 8 | 1,475
ependymoma 8 | 2,514
non-small cell lung cancer 8 | 2,798
pediatric high grade glioma 8 | 2,712
Hirschsprung Disease 7 | 11
atypical teratoid/rhabdoid tumor 7 | 1,095
cutaneous lupus erythematosus 7 | 1,056
ductal carcinoma in situ 7 | 1,745
interstitial cystitis 7 | 2,299
pancreatic cancer 7 | 2,300
pilocytic astrocytoma 7 | 3,086
primitive neuroectodermal tumor 7 | 3,031
Pick disease 6 | 1,893
gastric carcinoma 6 | 832
group 4 medulloblastoma 6 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
pituitary cancer 6 | 1,972
posterior fossa group A ependymoma 6 | 1,511
primary pancreatic ductal adenocarcinoma 6 | 1,271
sonic hedgehog group medulloblastoma 6 | 1,482
adult high grade glioma 5 | 2,148
diabetes mellitus 5 | 1,663
posterior fossa group B ependymoma 5 | 1,530
Heart disease 4 | 279
Waardenburg's syndrome 4 | 16
adrenocortical carcinoma 4 | 1,427
astrocytoma 4 | 1,493
fibroadenoma 4 | 557
non-small cell lung carcinoma 4 | 413
Amyotrophic Lateral Sclerosis 3 | 432
Atopic dermatitis 3 | 944
CCHS WITH HIRSCHSPRUNG DISEASE 3 | 5
Congenital central hypoventilation 3 | 6
Congenital central hypoventilation syndrome 3 | 6
Hirschsprung disease 1 3 | 9
Hypertension 3 | 293
Hypertensive disease 3 | 193
Intestinal obstruction 3 | 16
Kallmann Syndrome 3 | 33
Mammary Neoplasms 3 | 410
Multiple endocrine neoplasia type 2A 3 | 22
Multiple endocrine neoplasia type 2B 3 | 16
Obesity 3 | 616
Parkinson's disease 3 | 364
Pulmonary hypertension 3 | 52
Sensorineural hearing loss 3 | 107
Skin Neoplasms 3 | 49
WAARDENBURG SYNDROME, TYPE 4A 3 | 3
Waardenburg-Shah syndrome 3 | 3
acute quadriplegic myopathy 3 | 1,157
glioblastoma multiforme 3 | 347
inflammatory breast cancer 3 | 404
juvenile dermatomyositis 3 | 1,189
progressive supranuclear palsy 3 | 674
spina bifida 3 | 1,064
tuberculosis 3 | 1,563
urothelial carcinoma 3 | 318
Cerebrovascular disease 2 | 231
Down syndrome 2 | 548
Endometriosis 2 | 535
IGA Glomerulonephritis 2 | 454
Microphthalmia 2 | 79
Multiple Sclerosis 2 | 498
Neuropathy 2 | 210
Nevoid basal cell carcinoma syndrome 2 | 9
Status Epilepticus 2 | 85
active Crohn's disease 2 | 918
adrenocortical adenoma 2 | 134
aldosterone-producing adenoma 2 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
chronic rhinosinusitis 2 | 512
cystic fibrosis and chronic rhinosinusitis 2 | 213
esophageal adenocarcinoma 2 | 737
nasopharyngeal carcinoma 2 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
pulmonary arterial hypertension 2 | 36

Tissue

Digestive Tract 45 | 18,472
Endocrine System 45 | 18,511
Female tissues 45 | 18,646
Liver and Pancreas 45 | 18,135
Nervous System 45 | 18,560
Skin and soft tissues 45 | 18,114
Urinary Tract 45 | 18,443
Blood and immune system 44 | 17,994
Cardiovascular System 44 | 17,957
Male tissues 44 | 17,968
Respiratory system 43 | 17,483

Target Family

Non-IDG 29 | 11,969
Transcription Factor 9 | 1,400
GPCR 3 | 408
Kinase 3 | 634
Enzyme 1 | 4,146

GO Process

neural crest cell migration 45 | 45
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-3 EDN3 Tbio Non-IDG -2.95199 766.2 196
Coronin-1C CORO1C Tbio Non-IDG -1.43193 23.4 192
T-box transcription factor TBX1 TBX1 Tbio Transcription Factor -1.96037 90.3 180
Semaphorin-4C SEMA4C Tbio Non-IDG -1.65110 41.6 103
Semaphorin-3A SEMA3A Tbio Non-IDG -2.66866 501.0 166
Proto-oncogene tyrosine-protein kinase receptor Ret RET Tclin Kinase -3.40611 2681.1 809
ALX homeobox protein 1 ALX1 Tbio Transcription Factor -1.51988 27.5 102
Semaphorin-4B SEMA4B Tbio Non-IDG -1.80364 62.3 0
Semaphorin-6A SEMA6A Tbio Non-IDG -2.09298 116.1 189
Semaphorin-7A SEMA7A Tbio Non-IDG -1.93916 94.5 210