Development Level

Tbio 19 | 11,445
Tclin 5 | 613
Tchem 4 | 1,598

IMPC Phenotype

preweaning lethality, complete... 6 | 979
embryonic lethality prior to t... 3 | 278
decreased lean body mass 2 | 135
enlarged heart 2 | 210
impaired glucose tolerance 2 | 75
increased total body fat amoun... 2 | 134
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal heart morphology 1 | 162
abnormal pericardium morpholog... 1 | 26
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
embryonic lethality prior to o... 1 | 239
improved glucose tolerance 1 | 79
increased circulating thyroxin... 1 | 7
increased heart rate variabili... 1 | 7
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
limb grasping 1 | 41

Disease

Carcinoma 21 | 11,493
psoriasis 15 | 6,694
medulloblastoma, large-cell 14 | 6,241
ovarian cancer 14 | 8,520
Cancer 13 | 2,499
Breast cancer 10 | 3,578
atypical teratoid / rhabdoid tumor 10 | 5,112
breast carcinoma 10 | 1,638
group 3 medulloblastoma 10 | 4,104
invasive ductal carcinoma 10 | 2,951
lung cancer 10 | 4,740
osteosarcoma 10 | 7,950
Hirschsprung's disease 9 | 46
ependymoma 9 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
Constipation 8 | 181
Dyschezia 8 | 135
Intellectual disability 8 | 1,016
malignant mesothelioma 8 | 3,232
Abdominal Pain 7 | 98
Dull intelligence 7 | 645
Hirschsprung Disease 7 | 31
Intestinal Obstruction 7 | 31
Low intelligence 7 | 645
Megacolon 7 | 29
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
cystic fibrosis 7 | 1,696
glioblastoma 7 | 5,792
oligodendroglioma 7 | 2,850
pancreatic cancer 7 | 2,398
Bipolar Disorder 6 | 666
Breast Neoplasms 6 | 445
Broad flat nasal bridge 6 | 236
Cognitive delay 6 | 608
Global developmental delay 6 | 608
Kidney cancer 6 | 2,613
Mental and motor retardation 6 | 608
Muscle hypotonia 6 | 571
Nasal bridge wide 6 | 236
Nausea and vomiting 6 | 97
Sensorineural Hearing Loss (disorder) 6 | 284
Weight decreased 6 | 103
cutaneous lupus erythematosus 6 | 1,057
gastric carcinoma 6 | 807
group 4 medulloblastoma 6 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
lung carcinoma 6 | 2,843
ulcerative colitis 6 | 1,819
Autosomal recessive predisposition 5 | 1,442
Downward slant of palpebral fissure 5 | 158
Epilepsy 5 | 792
Mammary Neoplasms 5 | 425
Neoplasm Invasiveness 5 | 161
Orbital separation excessive 5 | 244
Pick disease 5 | 1,894
Schizophrenia 5 | 1,160
Small head 5 | 374
Thin hypoplastic alae nasi 5 | 51
diabetes mellitus 5 | 1,728
ductal carcinoma in situ 5 | 1,745
hypopigmented skin patch 5 | 59
interstitial cystitis 5 | 2,312
juvenile dermatomyositis 5 | 1,187
non-small cell lung cancer 5 | 2,890
primary pancreatic ductal adenocarcinoma 5 | 1,109
subependymal giant cell astrocytoma 5 | 2,287
Abnormality of vision 4 | 40
Acquired scoliosis 4 | 281
Amyotrophic lateral sclerosis 4 | 451
Bilateral fifth finger clinodactyly 4 | 110
Cleft Palate 4 | 271
Congenital deafness 4 | 185
Convex nasal bridge 4 | 57
Curvature of little finger 4 | 110
Curvature of spine 4 | 282
Deafness 4 | 198
Hearing Loss, Partial 4 | 185
Heart disease 4 | 306
Heart failure 4 | 162
Hypertension 4 | 396
Hypertensive disease 4 | 292
Liver cancer 4 | 604
Low set ears 4 | 181
Obesity 4 | 678
Pectus excavatum 4 | 100
Premature canities 4 | 24
Prominent nasal bridge 4 | 57
Seizures 4 | 596
acute quadriplegic myopathy 4 | 1,158
astrocytic glioma 4 | 2,597
colon cancer 4 | 1,478
fibroadenoma 4 | 559
hearing impairment 4 | 199
lung adenocarcinoma 4 | 2,716
pediatric high grade glioma 4 | 1,064
primitive neuroectodermal tumor 4 | 3,035
spina bifida 4 | 1,074

Tissue

Endocrine System 28 | 18,159
Female tissues 28 | 17,400
Male tissues 27 | 17,142
Nervous System 27 | 16,725
Skin and soft tissues 27 | 17,230
Urinary Tract 27 | 16,678
Digestive Tract 26 | 17,369
Liver and Pancreas 26 | 16,750
Blood and immune system 25 | 16,909
Respiratory system 25 | 16,393
Cardiovascular System 22 | 15,192

Target Family

Non-IDG 11 | 12,091
Transcription Factor 10 | 1,400
GPCR 3 | 408
Kinase 3 | 634
Enzyme 1 | 4,145

GO Process

neural crest cell migration 28 | 28
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
5-hydroxytryptamine receptor 2B HTR2B Tclin GPCR -2.66641 486.3 265
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
Transcription factor Ovo-like 2 OVOL2 Tbio Transcription Factor -1.20117 17.4 110
Neurturin NRTN Tbio Non-IDG -2.21792 170.4 331
Fibroblast growth factor 19 FGF19 Tbio Non-IDG -2.54882 334.2 305
T-box transcription factor TBX1 TBX1 Tbio Transcription Factor -1.99519 95.5 207
Ephrin-B1 EFNB1 Tbio Non-IDG -2.26015 197.6 359
Insulin gene enhancer protein ISL-1 ISL1 Tbio Transcription Factor -2.63352 410.3 382
Endothelin-3 EDN3 Tbio Non-IDG -2.96371 794.0 219
Transcription factor SOX-8 SOX8 Tbio Transcription Factor -1.36449 24.3 254