Development Level

Tbio 192 | 10,625
Tdark 37 | 7,003
Tchem 28 | 1,890
Tclin 18 | 602

Collection

Ion Channel: IDG Consortium (Targets) 3 | 102
Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

abnormal behavior 7 | 226
decreased total body fat amoun... 6 | 186
preweaning lethality, complete... 6 | 633
decreased bone mineral content 5 | 157
decreased circulating HDL chol... 5 | 77
abnormal bone structure 4 | 131
abnormal sleep behavior 4 | 63
decreased body weight 4 | 174
decreased circulating choleste... 4 | 85
decreased NK T cell number 3 | 28
decreased bone mineral density 3 | 126
decreased circulating glucose ... 3 | 121
decreased lean body mass 3 | 195
hyperactivity 3 | 108
increased fasted circulating g... 3 | 68
increased lean body mass 3 | 107
increased mean corpuscular vol... 3 | 91
increased or absent threshold ... 3 | 128
preweaning lethality, incomple... 3 | 260
decreased body length 2 | 108
decreased exploration in new e... 2 | 9
decreased grip strength 2 | 123
decreased startle reflex 2 | 48
embryonic lethality prior to o... 2 | 148
increased bone mineral content 2 | 92
male infertility 2 | 62
shortened RR interval 2 | 19
abnormal behavioral response t... 1 | 52
abnormal cornea morphology 1 | 24
abnormal lip morphology 1 | 2
abnormal liver morphology 1 | 5
abnormal response to tactile s... 1 | 16
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal startle reflex 1 | 14
abnormal vitreous body morphol... 1 | 7
absent startle reflex 1 | 15
corneal opacity 1 | 25
decreased CD4-positive, alpha ... 1 | 19
decreased NK cell number 1 | 16
decreased T-helper cell number 1 | 4
decreased blood urea nitrogen ... 1 | 31
decreased caudal vertebrae num... 1 | 49
decreased circulating alkaline... 1 | 41
decreased circulating aspartat... 1 | 27
decreased circulating calcium ... 1 | 33
decreased circulating free fat... 1 | 39
decreased circulating glycerol... 1 | 19
decreased circulating iron lev... 1 | 25
decreased circulating phosphat... 1 | 15
decreased circulating serum al... 1 | 79
decreased circulating triglyce... 1 | 83
decreased effector memory CD4-... 1 | 6
decreased effector memory CD8-... 1 | 24
decreased lumbar vertebrae num... 1 | 62
decreased neutrophil cell numb... 1 | 37
decreased prepulse inhibition 1 | 52
decreased red blood cell distr... 1 | 11
enlarged adrenal glands 1 | 3
enlarged kidney 1 | 7
enlarged uterus 1 | 3
female infertility 1 | 34
hydrometra 1 | 13
hypoactivity 1 | 89
increased CD4-positive, CD25-p... 1 | 18
increased body length 1 | 20
increased bone mineral density 1 | 52
increased circulating alkaline... 1 | 119
increased circulating aspartat... 1 | 17
increased circulating calcium ... 1 | 32
increased circulating chloride... 1 | 43
increased circulating creatini... 1 | 29
increased circulating free fat... 1 | 17
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased circulating phosphat... 1 | 24
increased circulating sodium l... 1 | 71
increased eosinophil cell numb... 1 | 9
increased exploration in new e... 1 | 56
increased grip strength 1 | 83
increased heart rate 1 | 17
increased red blood cell distr... 1 | 21
increased rib number 1 | 41
increased sacral vertebrae num... 1 | 62
increased thermal nociceptive ... 1 | 9
increased vertical activity 1 | 18
irregularly shaped pupil 1 | 7
jumpy 1 | 2
limb grasping 1 | 35
polycystic kidney 1 | 9
prenatal lethality prior to he... 1 | 64
short tibia 1 | 82
tremors 1 | 34

Disease

medulloblastoma, large-cell 134 | 6,234
ovarian cancer 118 | 8,491
osteosarcoma 116 | 7,933
glioblastoma 113 | 5,572
psoriasis 108 | 6,685
atypical teratoid / rhabdoid tumor 107 | 4,369
lung cancer 87 | 4,473
oligodendroglioma 87 | 2,849
pilocytic astrocytoma 81 | 3,086
primitive neuroectodermal tumor 71 | 3,031
Carcinoma 68 | 2,147
pediatric high grade glioma 68 | 2,712
subependymal giant cell astrocytoma 67 | 2,287
malignant mesothelioma 66 | 3,163
invasive ductal carcinoma 61 | 2,950
lung carcinoma 61 | 2,844
intraductal papillary-mucinous neoplasm (IPMN) 60 | 3,289
ependymoma 59 | 2,514
Breast cancer 58 | 3,098
astrocytic glioma 57 | 2,241
intraductal papillary-mucinous adenoma (IPMA) 57 | 2,956
group 4 medulloblastoma 55 | 1,875
Pick disease 53 | 1,893
pituitary cancer 52 | 1,972
intraductal papillary-mucinous carcinoma (IPMC) 48 | 2,988
group 3 medulloblastoma 46 | 2,254
lung adenocarcinoma 46 | 2,714
Cancer 43 | 2,346
cystic fibrosis 42 | 1,670
adult high grade glioma 41 | 2,148
colon cancer 41 | 1,475
astrocytoma 36 | 1,493
ductal carcinoma in situ 36 | 1,745
non-small cell lung cancer 36 | 2,798
posterior fossa group A ependymoma 36 | 1,511
ulcerative colitis 36 | 2,087
Intellectual disability 35 | 573
interstitial cystitis 35 | 2,299
medulloblastoma 34 | 1,524
breast carcinoma 33 | 1,614
posterior fossa group B ependymoma 33 | 1,530
pancreatic cancer 32 | 2,300
Alzheimer's disease 31 | 644
sonic hedgehog group medulloblastoma 31 | 1,482
Epilepsy 27 | 346
Schizophrenia 27 | 503
atypical teratoid/rhabdoid tumor 26 | 1,095
Neurodegenerative disease 24 | 383
tuberculosis 24 | 1,563
Down syndrome 22 | 548
Parkinson's disease 21 | 364
diabetes mellitus 21 | 1,663
gastric carcinoma 21 | 832
primary pancreatic ductal adenocarcinoma 21 | 1,271
adrenocortical carcinoma 20 | 1,427
spina bifida 20 | 1,064
acute quadriplegic myopathy 18 | 1,157
aldosterone-producing adenoma 18 | 664
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,795
Obesity 17 | 616
Atopic dermatitis 16 | 944
active Crohn's disease 16 | 918
cutaneous lupus erythematosus 16 | 1,056
Rheumatoid Arthritis 15 | 1,170
Autistic Disorder 14 | 320
Mammary Neoplasms 14 | 410
dermatomyositis 14 | 966
juvenile dermatomyositis 14 | 1,189
progressive supranuclear palsy 14 | 674
Bipolar Disorder 13 | 266
Neuropathy 13 | 210
Waldenstrons macroglobulinemia 13 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 13 | 499
Duchenne muscular dystrophy 12 | 602
Hirschsprung's disease 12 | 44
Multiple myeloma 12 | 1,327
Amyotrophic Lateral Sclerosis 11 | 432
Asthma 11 | 349
active ulcerative colitis 11 | 477
primary Sjogren syndrome 11 | 788
Cerebrovascular disease 10 | 231
Endometriosis 10 | 535
Seizures 10 | 95
nasopharyngeal carcinoma 10 | 1,056
nephrosclerosis 10 | 329
non primary Sjogren syndrome sicca 10 | 840
non-small cell lung carcinoma 10 | 413
Cleft palate 9 | 125
Lung Neoplasms 9 | 171
Osteoporosis 9 | 259
Vascular disease 9 | 281
Attention deficit hyperactivity disorder 8 | 156
Heart disease 8 | 279
Prostatic Neoplasms 8 | 471
chronic rhinosinusitis 8 | 512
esophageal adenocarcinoma 8 | 737
fibroadenoma 8 | 557
inflammatory breast cancer 8 | 404
pancreatic carcinoma 8 | 567
tuberculosis and treatment for 6 months 8 | 686

Tissue

Digestive Tract 272 | 18,472
Endocrine System 272 | 18,511
Female tissues 272 | 18,646
Nervous System 272 | 18,560
Urinary Tract 272 | 18,443
Liver and Pancreas 270 | 18,135
Male tissues 269 | 17,968
Skin and soft tissues 269 | 18,114
Cardiovascular System 268 | 17,957
Blood and immune system 267 | 17,994
Respiratory system 264 | 17,483

Target Family

Non-IDG 164 | 11,969
Enzyme 42 | 4,146
Transcription Factor 28 | 1,400
Kinase 10 | 634
Epigenetic 9 | 242
Ion Channel 9 | 341
GPCR 8 | 408
Nuclear Receptor 2 | 48
Transporter 2 | 473
TF/Epigenetic 1 | 38

GO Process

nervous system development 275 | 275
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myelin transcription factor 1-like protein MYT1L Tbio Transcription Factor -1.43180 24.8 41
Short transient receptor potential channel 5 TRPC5 Tchem Ion Channel -2.22055 159.7 209
Large neutral amino acids transporter small subunit 1 SLC7A5 Tbio Transporter -1.84839 135.6 220
Signal transducer and activator of transcription 3 STAT3 Tchem Transcription Factor -3.75815 5706.6 1539
RNA-binding protein Musashi homolog 1 MSI1 Tbio Non-IDG -1.95806 99.7 371
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.12726 13094.7 961
Ninjurin-2 NINJ2 Tbio Non-IDG -1.26697 17.4 43
Protocadherin alpha-4 PCDHA4 Tdark Non-IDG -0.35218 2.17 87
Protocadherin alpha-6 PCDHA6 Tdark Non-IDG -0.03779 1.24 164
Protocadherin alpha-7 PCDHA7 Tdark Non-IDG -0.12494 0.50 83