Development Level

Tbio 217 | 11,651
Tdark 62 | 6,593
Tchem 25 | 1,388
Tclin 17 | 612

Collection

RFA-RM-18-021 4 | 328
Ion Channel: IDG Consortium (T... 3 | 99
Kinase: IDG Consortium (Comple... 2 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 11 | 979
abnormal behavior 10 | 298
preweaning lethality, incomple... 8 | 499
abnormal bone structure 6 | 187
decreased total body fat amoun... 6 | 207
increased lean body mass 5 | 172
abnormal gait 4 | 69
abnormal sleep behavior 4 | 70
decreased bone mineral content 4 | 151
hyperactivity 4 | 148
decreased bone mineral density 3 | 126
decreased circulating HDL chol... 3 | 68
decreased circulating choleste... 3 | 93
decreased lean body mass 3 | 135
increased fasted circulating g... 3 | 76
increased vertical activity 3 | 24
short tibia 3 | 97
abnormal behavioral response t... 2 | 66
decreased body length 2 | 101
decreased body weight 2 | 161
decreased circulating alkaline... 2 | 46
decreased circulating glucose ... 2 | 126
decreased exploration in new e... 2 | 11
decreased grip strength 2 | 116
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
embryonic lethality prior to o... 2 | 239
increased bone mineral content 2 | 108
increased circulating calcium ... 2 | 34
increased circulating sodium l... 2 | 71
increased exploration in new e... 2 | 8
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased or absent threshold ... 2 | 101
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
shortened RR interval 2 | 17
abnormal cornea morphology 1 | 31
abnormal lens morphology 1 | 81
abnormal lip morphology 1 | 2
abnormal liver morphology 1 | 17
abnormal motor capabilities-co... 1 | 5
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal startle reflex 1 | 15
abnormal vitreous body morphol... 1 | 10
absent startle reflex 1 | 24
brachydactyly 1 | 19
cataract 1 | 92
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating glycerol... 1 | 16
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased red blood cell distr... 1 | 41
decreased vertical activity 1 | 208
enlarged adrenal glands 1 | 3
enlarged kidney 1 | 14
enlarged uterus 1 | 11
female infertility 1 | 60
hydrometra 1 | 53
hypoactivity 1 | 132
increased anxiety-related resp... 1 | 2
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating triglyce... 1 | 42
increased coping response 1 | 4
increased fluid intake 1 | 1
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased thermal nociceptive ... 1 | 9
irregularly shaped pupil 1 | 7
limb grasping 1 | 41
male infertility 1 | 123
polycystic kidney 1 | 15
prenatal lethality prior to he... 1 | 87
shortened ST segment 1 | 10
small spleen 1 | 19
syndactyly 1 | 23
tremors 1 | 39

Disease

Carcinoma 231 | 11,493
medulloblastoma, large-cell 142 | 6,241
ovarian cancer 127 | 8,520
atypical teratoid / rhabdoid tumor 126 | 5,112
osteosarcoma 126 | 7,950
psoriasis 125 | 6,694
ependymoma 121 | 4,679
glioblastoma 121 | 5,792
group 3 medulloblastoma 107 | 4,104
lung cancer 101 | 4,740
oligodendroglioma 99 | 2,850
Kidney cancer 98 | 2,613
adult high grade glioma 94 | 3,801
astrocytic glioma 89 | 2,597
Astrocytoma, Pilocytic 88 | 3,081
primitive neuroectodermal tumor 77 | 3,035
Breast cancer 71 | 3,578
malignant mesothelioma 71 | 3,232
subependymal giant cell astrocytoma 70 | 2,287
Schizophrenia 63 | 1,160
lung carcinoma 63 | 2,843
intraductal papillary-mucinous neoplasm (IPMN) 61 | 3,291
invasive ductal carcinoma 60 | 2,951
Pick disease 58 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 58 | 2,955
pituitary cancer 52 | 1,972
Epilepsy 50 | 792
Cancer 49 | 2,499
intraductal papillary-mucinous carcinoma (IPMC) 49 | 2,989
lung adenocarcinoma 49 | 2,716
Intellectual disability 48 | 1,016
group 4 medulloblastoma 47 | 1,855
cystic fibrosis 44 | 1,696
pancreatic cancer 44 | 2,398
non-small cell lung cancer 43 | 2,890
colon cancer 41 | 1,478
ductal carcinoma in situ 39 | 1,745
Seizures 38 | 596
Bipolar Disorder 37 | 666
ulcerative colitis 37 | 1,819
interstitial cystitis 35 | 2,312
tuberculosis 35 | 2,010
Dull intelligence 34 | 645
Low intelligence 34 | 645
Mental Retardation 34 | 645
Mental deficiency 34 | 645
Poor school performance 34 | 645
breast carcinoma 33 | 1,638
Muscle hypotonia 30 | 571
Autosomal recessive predisposition 29 | 1,442
Liver cancer 28 | 604
Melanoma 28 | 711
Alzheimer's disease 27 | 658
Cognitive delay 26 | 608
Global developmental delay 26 | 608
Mental and motor retardation 26 | 608
Neurodegenerative disease 26 | 414
diabetes mellitus 24 | 1,728
Autistic Disorder 23 | 364
Skin cancer 23 | 469
primary pancreatic ductal adenocarcinoma 23 | 1,109
Cerebellar Ataxia 22 | 304
Depressive disorder 22 | 409
Down syndrome 22 | 499
Parkinson's disease 21 | 392
Strabismus 21 | 270
adrenocortical carcinoma 21 | 1,428
gastric carcinoma 21 | 807
pediatric high grade glioma 21 | 1,064
Mental Depression 20 | 333
Rheumatoid arthritis 20 | 1,191
acute quadriplegic myopathy 20 | 1,158
astrocytoma 20 | 1,146
Endometrial cancer 19 | 311
Major Depressive Disorder 19 | 301
Obesity 19 | 678
Short stature 19 | 531
aldosterone-producing adenoma 19 | 665
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,962
Neuropathy 18 | 261
spina bifida 18 | 1,074
active Crohn's disease 17 | 922
Nystagmus 16 | 317
Small head 16 | 374
Unipolar Depression 16 | 250
cutaneous lupus erythematosus 16 | 1,057
juvenile dermatomyositis 16 | 1,187
Amyotrophic lateral sclerosis 15 | 451
Atopic dermatitis 15 | 952
Attention deficit hyperactivity disorder 15 | 278
Breast Neoplasms 15 | 445
Mammary Neoplasms 15 | 425
active ulcerative colitis 15 | 764
medulloblastoma 15 | 720
progressive supranuclear palsy 15 | 676
Cleft Palate 14 | 271
Mood Disorders 14 | 184
Waldenstrons macroglobulinemia 14 | 765
autosomal dominant Emery-Dreifuss muscular dystrophy 14 | 510
dermatomyositis 14 | 966

Tissue

Endocrine System 311 | 18,159
Nervous System 311 | 16,725
Female tissues 307 | 17,400
Digestive Tract 305 | 17,369
Male tissues 304 | 17,142
Skin and soft tissues 300 | 17,230
Liver and Pancreas 296 | 16,750
Urinary Tract 294 | 16,678
Blood and immune system 288 | 16,909
Respiratory system 283 | 16,393
Cardiovascular System 265 | 15,192

Target Family

Non-IDG 202 | 12,091
Enzyme 42 | 4,145
Transcription Factor 30 | 1,400
Kinase 15 | 634
Epigenetic 9 | 242
Ion Channel 9 | 344
GPCR 8 | 408
Nuclear Receptor 2 | 48
TF/Epigenetic 2 | 38
Transporter 2 | 473

GO Process

nervous system development 321 | 321
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription factor HES-1 HES1 Tbio Transcription Factor -1.77409 55.5 444
Disks large homolog 2 DLG2 Tbio Non-IDG -1.75838 53.6 227
Basic leucine zipper and W2 domain-containing protein 2 BZW2 Tbio Non-IDG -0.20261 1.21 83
RNA binding protein fox-1 homolog 1 RBFOX1 Tbio Non-IDG -2.00815 99.2 207
Protein mab-21-like 2 MAB21L2 Tbio Non-IDG -1.11941 14.4 11
Chordin-like protein 1 CHRDL1 Tbio Non-IDG -1.99743 97.9 191
E3 ubiquitin-protein ligase MYLIP MYLIP Tbio Enzyme -2.05580 115.6 135
Protein inturned INTU Tbio Non-IDG -1.76006 53.9 56
Roundabout homolog 1 ROBO1 Tbio Non-IDG -2.15518 129.8 261
Short transient receptor potential channel 5 TRPC5 Tchem Ion Channel -2.25002 172.0 220