Development Level

Tbio 6 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
embryonic lethality prior to o... 2 | 239
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal nail morphology 1 | 8
abnormal retina morphology 1 | 71
absent spleen 1 | 3
cataract 1 | 92
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
hypoactivity 1 | 132
increased circulating iron lev... 1 | 30
limb grasping 1 | 41
preweaning lethality, incomple... 1 | 499

Disease

malignant mesothelioma 7 | 3,232
Carcinoma 6 | 11,493
Cancer 5 | 2,499
lung cancer 5 | 4,740
osteosarcoma 5 | 7,950
ovarian cancer 5 | 8,520
atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
ulcerative colitis 4 | 1,819
Astrocytoma, Pilocytic 3 | 3,081
Atopic dermatitis 3 | 952
Breast cancer 3 | 3,578
adult high grade glioma 3 | 3,801
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung carcinoma 3 | 2,843
medulloblastoma, large-cell 3 | 6,241
primitive neuroectodermal tumor 3 | 3,035
Endometriosis 2 | 540
Kidney cancer 2 | 2,613
Neurodegenerative disease 2 | 414
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
adrenocortical carcinoma 2 | 1,428
astrocytic glioma 2 | 2,597
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
gastric carcinoma 2 | 807
hereditary spastic paraplegia 2 | 318
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
medulloblastoma 2 | 720
oligodendroglioma 2 | 2,850
psoriasis 2 | 6,694
spina bifida 2 | 1,074
tuberculosis 2 | 2,010
Abdominal Pain 1 | 98
Abnormality of metabolism/homeostasis 1 | 134
Ataxia, Appendicular 1 | 25
Ataxia, Spinocerebellar 1 | 16
Autosomal dominant cerebellar ataxia 1 | 33
Basal cell carcinoma 1 | 54
Basal cell nevi 1 | 23
Blepharoptosis 1 | 231
Cerebellar Dysmetria 1 | 56
Colonic Polyps 1 | 3
Congenital hypoplasia of breast 1 | 25
Constipation 1 | 181
Decreased bone mineral density Z score 1 | 31
Decreased fertility 1 | 33
Deglutition Disorders 1 | 132
Delayed Puberty 1 | 97
Dyschezia 1 | 135
Dysdiadochokinesis 1 | 25
Dysmetric saccades 1 | 9
Early myoclonic encephalopathy 1 | 15
Endometrial Neoplasms 1 | 55
Epilepsies, Myoclonic 1 | 32
Fragile X syndrome 1 | 34
Frontotemporal dementia 1 | 51
Gaucher disease type 1 1 | 180
Generalized myoclonic seizures 1 | 30
Granulosa cell tumor 1 | 6
Hirschsprung Disease 1 | 31
Hirschsprung's disease 1 | 46
Hypogonadism, Isolated Hypogonadotropic 1 | 71
Hypogonadotropic hypogonadism 1 | 89
Increased intramyocellular lipid droplets 1 | 13
Intestinal Obstruction 1 | 31
Liver diseases 1 | 87
Lower limb hyperreflexia 1 | 10
Lymphedema 1 | 42
Megacolon 1 | 29
Muscle Weakness 1 | 170
Myoclonic Epilepsies, Progressive 1 | 44
Myoclonus 1 | 74
Nausea and vomiting 1 | 97
Neurogenic muscle atrophy, especially in the lower limbs 1 | 139
Nystagmus, End-Position 1 | 12
Oligospermia 1 | 36
Ophthalmoparesis 1 | 11
Papillary thyroid carcinoma 1 | 43
Paraparesis, Spastic 1 | 16
Prion disease 1 | 16
Ptosis 1 | 48
Renal Cell Carcinoma 1 | 214
Rhabdomyosarcoma 1 | 39
Seminoma 1 | 15
Slowed saccades 1 | 12
Small testicle 1 | 75
Spastic Ataxia 1 | 18
Spinocerebellar Ataxias 1 | 34
Tonic - clonic seizures 1 | 44
Weight decreased 1 | 103
Wilms Tumor 1 | 28
ovarian neoplasm 1 | 99
permanent atrial fibrillation 1 | 45
sarcoidosis 1 | 370

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Non-IDG 5 | 12,091
Enzyme 3 | 4,145
Kinase 1 | 634

GO Process

nerve development 9 | 9
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neurturin NRTN Tbio Non-IDG -2.21792 170.4 331
AFG3-like protein 2 AFG3L2 Tbio Enzyme -1.58716 39.9 164
Semaphorin-3A SEMA3A Tbio Non-IDG -2.70786 548.1 185
Semaphorin-3F SEMA3F Tbio Non-IDG -1.97011 94.5 125
Integrin-linked protein kinase ILK Tchem Kinase -2.75450 679.1 608
Endoribonuclease Dicer DICER1 Tbio Enzyme -3.34177 2054.3 327
Cathepsin L2 CTSV Tchem Enzyme -1.70732 46.3 237
Neuropilin-1 NRP1 Tchem Non-IDG -2.71062 531.2 587
Neuropilin-2 NRP2 Tbio Non-IDG -2.07484 128.2 305