Development Level

Tbio 13 | 11,445

IMPC Phenotype

decreased bone mineral density 2 | 126
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
decreased mature B cell number 1 | 7
decreased mean corpuscular vol... 1 | 79
enlarged spleen 1 | 41
preweaning lethality, complete... 1 | 979
scaly skin 1 | 4

Disease

lung cancer 8 | 4,740
ovarian cancer 8 | 8,520
Carcinoma 7 | 11,493
glioblastoma 7 | 5,792
osteosarcoma 7 | 7,950
psoriasis 7 | 6,694
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
juvenile dermatomyositis 5 | 1,187
lung carcinoma 4 | 2,843
pancreatic cancer 4 | 2,398
Astrocytoma, Pilocytic 3 | 3,081
Rheumatoid arthritis 3 | 1,191
active ulcerative colitis 3 | 764
acute quadriplegic myopathy 3 | 1,158
colon cancer 3 | 1,478
cutaneous lupus erythematosus 3 | 1,057
ependymoma 3 | 4,679
esophageal adenocarcinoma 3 | 737
group 3 medulloblastoma 3 | 4,104
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
pituitary cancer 3 | 1,972
tuberculosis 3 | 2,010
Cancer 2 | 2,499
Dull intelligence 2 | 645
Intellectual disability 2 | 1,016
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Multiple Sclerosis 2 | 540
Opitz-GBBB syndrome 2 | 18
Poor school performance 2 | 645
acute myeloid leukemia 2 | 783
adult high grade glioma 2 | 3,801
aldosterone-producing adenoma 2 | 665
astrocytoma 2 | 1,146
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
inflammatory breast cancer 2 | 286
non-small cell lung cancer 2 | 2,890
subependymal giant cell astrocytoma 2 | 2,287
urothelial carcinoma 2 | 318
Absent reflex 1 | 92
Absent speech 1 | 43
Absent tendon reflex 1 | 92
Acquired metabolic disease 1 | 336
Alopecia 1 | 115
Amyotrophic lateral sclerosis type 3 1 | 17
Antiphospholipid syndrome 1 | 19
Bell Palsy 1 | 58
COPD 1 | 118
Cachexia 1 | 50
Decreased tendon reflex 1 | 122
Electromyogram abnormal 1 | 49
FG syndrome 1 | 16
Facial Paresis 1 | 59
Facial muscle weakness of muscles innervated by CN VII 1 | 58
Gowers sign 1 | 24
Gowers sign present 1 | 24
Highly variable clinical phenotype 1 | 150
Highly variable phenotype and severity 1 | 150
Highly variable phenotype, even within families 1 | 150
Hyperactive behavior 1 | 91
Inflammation 1 | 120
Influenza 1 | 142
Influenza, Human 1 | 51
Keratoconjunctivitis sicca 1 | 25
Kidney Diseases 1 | 114
Leukopenia 1 | 72
Liver Cirrhosis 1 | 181
Lupus erythematosus 1 | 57
Muscle biopsy shows dystrophic changes 1 | 39
Muscular atrophy 1 | 71
Muscular dystrophy 1 | 75
Myositis 1 | 30
Pain agnosia 1 | 104
Phenotypic variability 1 | 150
Prenatal onset 1 | 139
Purpura 1 | 43
Reflex, Deep Tendon, Absent 1 | 92
Retinal Diseases 1 | 55
Rheumatic disease 1 | 8
Sjogren's syndrome 1 | 26
Slow progression 1 | 89
Systemic lupus erythematosus 1 | 194
Tall stature 1 | 34
Telangiectasis 1 | 36
Waddling gait 1 | 34
West Nile encephalitis 1 | 9
X- linked recessive 1 | 110
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
interstitial lung disease 1 | 298
limb-girdle muscular dystrophy 1 | 37
non-inflammatory breast cancer 1 | 66
nonverbal 1 | 43
posterior fossa group A ependymoma 1 | 468
sarcoidosis 1 | 370
tuberculosis and treatment for 6 months 1 | 409

Tissue

Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678
Blood and immune system 12 | 16,909
Cardiovascular System 12 | 15,192
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393

Target Family

Enzyme 8 | 4,145
Non-IDG 4 | 12,091
TF/Epigenetic 1 | 38

GO Process

negative regulation of viral t... 13 | 13
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Probable E3 ubiquitin-protein ligase MID2 MID2 Tbio Enzyme -2.49198 303.4 152
E3 ubiquitin-protein ligase TRIM62 TRIM62 Tbio Enzyme -0.68317 7.51 147
Interferon-induced transmembrane protein 3 IFITM3 Tbio Non-IDG -1.93256 151.2 200
E3 ubiquitin-protein ligase TRIM31 TRIM31 Tbio Enzyme -2.19476 152.7 142
Probable E3 ubiquitin-protein ligase TRIM8 TRIM8 Tbio Enzyme -1.50607 33.0 118
Tripartite motif-containing protein 14 TRIM14 Tbio Non-IDG -0.97373 8.40 93
E3 ubiquitin-protein ligase TRIM21 TRIM21 Tbio Enzyme -3.03008 1099.3 268
Zinc finger protein RFP TRIM27 Tbio Non-IDG -1.52798 33.0 172
mRNA decay activator protein ZFP36 ZFP36 Tbio Non-IDG -2.42848 236.6 0
E3 ubiquitin-protein ligase TRIM13 TRIM13 Tbio Enzyme -3.00079 962.9 185