Development Level

Tbio 59 | 11,651
Tchem 5 | 1,388
Tclin 5 | 612
Tdark 3 | 6,593

IMPC Phenotype

preweaning lethality, complete... 11 | 979
abnormal embryo size 4 | 220
embryonic lethality prior to t... 4 | 278
embryonic growth retardation 3 | 106
embryonic lethality prior to o... 3 | 239
abnormal heart morphology 2 | 162
abnormal placenta size 2 | 20
anophthalmia 2 | 33
increased hematocrit 2 | 46
abnormal behavioral response t... 1 | 66
abnormal craniofacial morpholo... 1 | 33
abnormal forebrain morphology 1 | 10
abnormal head shape 1 | 10
abnormal hindbrain morphology 1 | 10
abnormal joint morphology 1 | 23
abnormal kidney morphology 1 | 65
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal placenta morphology 1 | 5
abnormal skin coloration 1 | 25
brachydactyly 1 | 19
decreased caudal vertebrae num... 1 | 53
decreased circulating alanine ... 1 | 47
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating total pr... 1 | 49
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased red blood cell distr... 1 | 41
decreased vertical activity 1 | 208
edema 1 | 59
enlarged heart 1 | 210
female infertility 1 | 60
increased basophil cell number 1 | 7
increased circulating alanine ... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating phosphat... 1 | 26
increased eosinophil cell numb... 1 | 11
increased erythrocyte cell num... 1 | 39
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
male infertility 1 | 123
microphthalmia 1 | 26
pallor 1 | 34
prenatal lethality 1 | 28
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
syndactyly 1 | 23
urinary bladder obstruction 1 | 4

Disease

ovarian cancer 52 | 8,520
lung cancer 34 | 4,740
Carcinoma 30 | 11,493
psoriasis 30 | 6,694
Multiple myeloma 28 | 1,332
glioblastoma 27 | 5,792
osteosarcoma 26 | 7,950
medulloblastoma, large-cell 18 | 6,241
Breast cancer 16 | 3,578
atypical teratoid / rhabdoid tumor 16 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
Cancer 15 | 2,499
group 3 medulloblastoma 15 | 4,104
HIV Infections 14 | 102
ependymoma 14 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
invasive ductal carcinoma 13 | 2,951
malignant mesothelioma 13 | 3,232
non-small cell lung cancer 13 | 2,890
Waldenstrons macroglobulinemia 12 | 765
adult high grade glioma 12 | 3,801
dermatomyositis 12 | 966
adrenocortical carcinoma 11 | 1,428
lung adenocarcinoma 11 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
pancreatic cancer 10 | 2,398
primitive neuroectodermal tumor 10 | 3,035
astrocytoma 9 | 1,146
colon cancer 8 | 1,478
non primary Sjogren syndrome sicca 8 | 891
oligodendroglioma 8 | 2,850
primary Sjogren syndrome 8 | 735
Atopic dermatitis 7 | 952
Endometriosis 7 | 540
breast carcinoma 7 | 1,638
diabetes mellitus 7 | 1,728
ductal carcinoma in situ 7 | 1,745
Pick disease 6 | 1,894
astrocytic glioma 6 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
Astrocytoma, Pilocytic 5 | 3,081
Liver Cirrhosis, Experimental 5 | 769
Mantle cell lymphoma 5 | 23
active Crohn's disease 5 | 922
acute quadriplegic myopathy 5 | 1,158
esophageal adenocarcinoma 5 | 737
interstitial cystitis 5 | 2,312
lung carcinoma 5 | 2,843
nasopharyngeal carcinoma 5 | 1,058
subependymal giant cell astrocytoma 5 | 2,287
Esophageal Squamous Cell Carcinoma 4 | 77
Osteoporosis 4 | 363
Squamous cell carcinoma of esophagus 4 | 77
juvenile dermatomyositis 4 | 1,187
pituitary cancer 4 | 1,972
tuberculosis 4 | 2,010
ulcerative colitis 4 | 1,819
Anemia 3 | 365
Hypoplastic mandible condyle 3 | 275
Intellectual disability 3 | 1,016
Mandibular hypoplasia 3 | 275
Micrognathism 3 | 275
Polycystic ovary syndrome 3 | 360
acute myeloid leukemia 3 | 783
cutaneous lupus erythematosus 3 | 1,057
group 4 medulloblastoma 3 | 1,855
primary pancreatic ductal adenocarcinoma 3 | 1,109
Abnormally small eyeball 2 | 97
Acquired metabolic disease 2 | 336
Alzheimer's disease 2 | 658
Animal Mammary Neoplasms 2 | 136
Autosomal recessive predisposition 2 | 1,442
Clouding of corneal stroma 2 | 50
Cognitive delay 2 | 608
Congenital Epicanthus 2 | 177
Congestive heart failure 2 | 113
Corneal Opacity 2 | 53
Decreased size of eyeball 2 | 97
Duchenne muscular dystrophy 2 | 601
Dull intelligence 2 | 645
Glaucoma 2 | 239
Global developmental delay 2 | 608
Kidney cancer 2 | 2,613
Lens Opacities 2 | 231
Mammary Neoplasms, Experimental 2 | 154
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Muscle biopsy shows dystrophic changes 2 | 39
Muscular dystrophy 2 | 75
Polyhydramnios 2 | 108
Poor school performance 2 | 645
Profound Mental Retardation 2 | 31
Profound intellectual disabilities 2 | 31
Rheumatoid arthritis 2 | 1,191
Triangular face 2 | 58
Uranostaphyloschisis 2 | 167
hepatocellular carcinoma 2 | 547
posterior fossa group A ependymoma 2 | 468
progressive supranuclear palsy 2 | 676
sonic hedgehog group medulloblastoma 2 | 467

Tissue

Blood and immune system 72 | 16,909
Digestive Tract 72 | 17,369
Endocrine System 72 | 18,159
Female tissues 72 | 17,400
Male tissues 72 | 17,142
Skin and soft tissues 72 | 17,230
Cardiovascular System 71 | 15,192
Liver and Pancreas 71 | 16,750
Nervous System 71 | 16,725
Respiratory system 71 | 16,393
Urinary Tract 71 | 16,678

Target Family

Enzyme 47 | 4,145
Non-IDG 22 | 12,091
Kinase 3 | 634

GO Process

negative regulation of ubiquit... 72 | 72
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
F-box only protein 5 FBXO5 Tbio Non-IDG -1.71993 56.0 137
26S proteasome regulatory subunit 6A PSMC3 Tbio Enzyme -1.29086 19.3 302
Anaphase-promoting complex subunit 5 ANAPC5 Tbio Enzyme -1.45912 28.7 251
26S proteasome non-ATPase regulatory subunit 13 PSMD13 Tbio Enzyme -1.09295 11.9 110
26S proteasome non-ATPase regulatory subunit 3 PSMD3 Tbio Enzyme -1.22269 15.9 168
Mitotic checkpoint protein BUB3 BUB3 Tbio Non-IDG -1.93368 76.1 256
Fizzy-related protein homolog FZR1 Tbio Non-IDG -1.78590 63.2 228
Proteasome activator complex subunit 3 PSME3 Tbio Non-IDG -1.87037 83.7 245
Cell division cycle protein 20 homolog CDC20 Tbio Non-IDG -2.60409 401.5 393
Proteasome activator complex subunit 2 PSME2 Tbio Non-IDG -1.47440 29.1 305