Development Level

Tbio 9 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

decreased body weight 1 | 161
decreased lean body mass 1 | 135
embryonic lethality prior to t... 1 | 278
impaired glucose tolerance 1 | 75
increased circulating triglyce... 1 | 42
increased mean corpuscular hem... 1 | 96
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 8 | 11,493
ovarian cancer 8 | 8,520
osteosarcoma 6 | 7,950
psoriasis 5 | 6,694
Breast cancer 4 | 3,578
Cancer 4 | 2,499
Multiple myeloma 4 | 1,332
Epilepsy 3 | 792
Intellectual disability 3 | 1,016
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
Carcinoma, Hepatocellular 2 | 228
Cognitive delay 2 | 608
Dull intelligence 2 | 645
Flexion contracture of proximal interphalangeal joint 2 | 75
Global developmental delay 2 | 608
Holoprosencephaly 2 | 56
Kidney cancer 2 | 2,613
Liver carcinoma 2 | 240
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Microcephaly 2 | 166
Parkinson's disease 2 | 392
Poor school performance 2 | 645
Seizures 2 | 596
Strabismus 2 | 270
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
atypical teratoid / rhabdoid tumor 2 | 5,112
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
pancreatic cancer 2 | 2,398
spina bifida 2 | 1,074
Abnormally low-pitched voice 1 | 6
Abnormally small eyeball on both sides 1 | 5
Ameloblastoma 1 | 24
Ataxia telangiectasia 1 | 34
Baller-Gerold syndrome 1 | 12
Basal cell carcinoma of skin 1 | 2
Bilateral nanophthalmos 1 | 5
Biliary tract cancer 1 | 19
Bloom syndrome 1 | 29
Calcaneovalgus deformity 1 | 8
Choanal Atresia 1 | 42
Coloboma 1 | 51
Coloboma, Ocular, Autosomal Dominant 1 | 6
Congenital duplication of uterus 1 | 3
Craniosynostoses 1 | 16
Deep philtrum 1 | 21
Deep-set nails 1 | 2
Depressed philtrum 1 | 21
Diastasis recti 1 | 9
Diffuse large B-cell lymphoma 1 | 39
Dilation of lateral ventricles 1 | 4
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 54 1 | 1
Familial schizencephaly 1 | 4
Fetal alcohol syndrome 1 | 22
Hemiparesis 1 | 34
Holoprosencephaly 3 1 | 7
Hyperkyphosis 1 | 111
Hypoplastic iliac wing 1 | 19
Hypoplastic tibiae-postaxial polydactyly syndrome 1 | 2
Hypoplastic toenails 1 | 22
Increased hepatocellular carcinoma risk 1 | 27
Increased incidence of hepatocellular carcinoma 1 | 27
Kuhnt-Junius degeneration 1 | 14
Kyphosis deformity of spine 1 | 114
Large hand 1 | 18
Leukemia, Megakaryoblastic, of Down Syndrome 1 | 8
Lymphoma, Large B-Cell, Diffuse 1 | 34
Micronodular cirrhosis 1 | 12
Microphthalmia, bilateral 1 | 5
Narrow nose 1 | 20
Overriding toe 1 | 10
POLYDACTYLY, PREAXIAL II (disorder) 1 | 2
Parkinson Disease, Secondary 1 | 9
Pinched bridge of nose 1 | 14
Pinched nasal bridge 1 | 14
Polydactyly preaxial type 1 1 | 9
Polydactyly, Preaxial 2 1 | 2
Porencephaly 1 | 20
Rapadilino syndrome 1 | 7
Rothmund-Thomson syndrome 1 | 19
SOLITARY MEDIAN MAXILLARY CENTRAL INCISOR 1 | 5
Schizencephaly 1 | 4
Secondary Parkinson Disease 1 | 10
Short ribs 1 | 30
Smith-Lemli-Opitz syndrome 1 | 9
Subacute progressive viral hepatitis 1 | 9
Syndactyly, Type IV 1 | 2
Thin nails 1 | 5
Thyroid cancer 1 | 36
Tibia, Hypoplasia of, with Polydactyly 1 | 2
Uterus bilocularis 1 | 3
Werner syndrome 1 | 29

Tissue

Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678
Blood and immune system 10 | 16,909
Cardiovascular System 10 | 15,192

Target Family

Non-IDG 7 | 12,091
Enzyme 3 | 4,145
Epigenetic 1 | 242

GO Process

negative regulation of transcr... 11 | 11
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Negative elongation factor B NELFB Tbio Non-IDG -1.16040 16.4 158
ATP-dependent DNA helicase Q5 RECQL5 Tbio Enzyme -1.67373 56.2 148
Heterogeneous nuclear ribonucleoprotein U HNRNPU Tbio Non-IDG -2.33813 207.8 169
E3 ubiquitin-protein ligase RNF8 RNF8 Tbio Enzyme -1.80196 70.0 250
Transcription elongation factor SPT4 SUPT4H1 Tbio Non-IDG -1.65513 43.4 92
E3 ubiquitin-protein ligase RNF168 RNF168 Tbio Enzyme -1.53836 33.4 166
E2F-associated phosphoprotein EAPP Tbio Non-IDG -1.48763 32.4 94
Axin-1 AXIN1 Tbio Non-IDG -2.52218 301.0 370
Sonic hedgehog protein SHH Tchem Non-IDG -3.44287 2879.1 383
Histone-lysine N-methyltransferase EZH2 EZH2 Tchem Epigenetic -3.16893 1399.0 606