Development Level

Tbio 13 | 11,445

IMPC Phenotype

increased fasted circulating g... 2 | 76
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal lens morphology 1 | 81
abnormal sleep behavior 1 | 70
cataract 1 | 92
decreased circulating serum al... 1 | 82
decreased fasted circulating g... 1 | 65
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
enlarged adrenal glands 1 | 3
enlarged kidney 1 | 14
enlarged uterus 1 | 11
hydrometra 1 | 53
impaired righting response 1 | 26
increased circulating thyroxin... 1 | 7
increased heart weight 1 | 62
irregularly shaped pupil 1 | 7
polycystic kidney 1 | 15
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 10 | 11,493
ovarian cancer 10 | 8,520
pancreatic cancer 10 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
invasive ductal carcinoma 8 | 2,951
medulloblastoma, large-cell 8 | 6,241
osteosarcoma 8 | 7,950
atypical teratoid / rhabdoid tumor 7 | 5,112
Breast cancer 6 | 3,578
glioblastoma 6 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
lung carcinoma 6 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
psoriasis 6 | 6,694
Astrocytoma, Pilocytic 5 | 3,081
adult high grade glioma 5 | 3,801
cystic fibrosis 5 | 1,696
ductal carcinoma in situ 5 | 1,745
interstitial cystitis 5 | 2,312
lung adenocarcinoma 5 | 2,716
lung cancer 5 | 4,740
malignant mesothelioma 5 | 3,232
oligodendroglioma 5 | 2,850
astrocytic glioma 4 | 2,597
breast carcinoma 4 | 1,638
cutaneous lupus erythematosus 4 | 1,057
ependymoma 4 | 4,679
non-small cell lung cancer 4 | 2,890
primary pancreatic ductal adenocarcinoma 4 | 1,109
primitive neuroectodermal tumor 4 | 3,035
Atopic dermatitis 3 | 952
Cancer 3 | 2,499
Duchenne muscular dystrophy 3 | 601
acute quadriplegic myopathy 3 | 1,158
astrocytoma 3 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
dermatomyositis 3 | 966
esophageal adenocarcinoma 3 | 737
fibroadenoma 3 | 559
gastric carcinoma 3 | 807
group 3 medulloblastoma 3 | 4,104
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
juvenile dermatomyositis 3 | 1,187
limb girdle muscular dystrophy 2A 3 | 213
nasopharyngeal carcinoma 3 | 1,058
pituitary cancer 3 | 1,972
tuberculosis 3 | 2,010
Asthma 2 | 385
Endometriosis 2 | 540
Kidney cancer 2 | 2,613
Multiple Sclerosis 2 | 540
Pick disease 2 | 1,894
Rheumatoid arthritis 2 | 1,191
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
acute myeloid leukemia 2 | 783
fascioscapulohumeral muscular dystrophy 2 | 100
gastric cancer 2 | 459
hepatocellular carcinoma 2 | 547
mucosa-associated lymphoid tissue lymphoma 2 | 484
primary Sjogren syndrome 2 | 735
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Alcoholic Intoxication, Chronic 1 | 289
Amyotrophic lateral sclerosis 1 | 451
Asthma, Aspirin-Induced 1 | 13
Cerebral atrophy 1 | 178
Cerebral palsy 1 | 40
Cholestasis 1 | 155
Colorectal Neoplasms 1 | 243
Corneal dystrophy 1 | 24
Craniofacial Abnormalities 1 | 151
Degenerative brain disorder 1 | 100
Dilated ventricles (finding) 1 | 121
Focal glomerulosclerosis 1 | 37
Glomerulonephritis, IGA 1 | 34
Glomerulosclerosis, Focal Segmental 1 | 28
Heart disease 1 | 306
Hypoalbuminemia 1 | 24
IGA Glomerulonephritis 1 | 50
Influenza 1 | 142
Influenza, Human 1 | 51
Kidney disease 1 | 430
Liver Cirrhosis, Experimental 1 | 769
Low Vision 1 | 174
Melanoma 1 | 711
Osteoporosis 1 | 363
Proteinuria 1 | 144
Quadriplegia 1 | 20
Reperfusion Injury 1 | 86
Supratentorial atrophy 1 | 94
Syndactyly of the toes 1 | 45
Visual Impairment 1 | 174
X-linked cerebral adrenoleukodystrophy 1 | 116
medulloblastoma 1 | 720
posterior fossa group A ependymoma 1 | 468
pulmonary arterial hypertension 1 | 75
sarcoidosis 1 | 370
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678

Target Family

Non-IDG 13 | 12,091

GO Process

negative regulation of substra... 13 | 13
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-actinin-4 ACTN4 Tbio Non-IDG -2.22522 178.2 300
Integrin beta-1-binding protein 1 ITGB1BP1 Tbio Non-IDG -1.23128 20.8 138
Melanotransferrin MELTF Tbio Non-IDG -1.94641 92.5 191
Fibulin-1 FBLN1 Tbio Non-IDG -1.97380 101.1 218
AP-1 complex-associated regulatory protein AP1AR Tbio Non-IDG -2.00840 96.3 21
Periostin POSTN Tbio Non-IDG -2.84323 747.5 396
Tumor-associated calcium signal transducer 2 TACSTD2 Tbio Non-IDG -2.85837 711.1 440
Protein RCC2 RCC2 Tbio Non-IDG -1.49831 31.4 148
KN motif and ankyrin repeat domain-containing protein 1 KANK1 Tbio Non-IDG -1.52122 36.6 64
Coronin-1C CORO1C Tbio Non-IDG -1.47050 32.6 211