Development Level

Tbio 8 | 11,445
Tchem 5 | 1,598

Collection

Kinase: IDG Consortium (Comple... 2 | 37

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal bone structure 1 | 187
abnormal vertebrae morphology 1 | 18
decreased bone mineral content 1 | 151
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
increased fasted circulating g... 1 | 76
increased startle reflex 1 | 112

Disease

Carcinoma 9 | 11,493
ovarian cancer 8 | 8,520
osteosarcoma 7 | 7,950
ependymoma 6 | 4,679
glioblastoma 6 | 5,792
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
lung cancer 6 | 4,740
medulloblastoma, large-cell 6 | 6,241
psoriasis 6 | 6,694
Astrocytoma, Pilocytic 5 | 3,081
Breast cancer 5 | 3,578
Kidney cancer 5 | 2,613
cystic fibrosis 5 | 1,696
gastric carcinoma 5 | 807
oligodendroglioma 5 | 2,850
primitive neuroectodermal tumor 5 | 3,035
Breast Neoplasms 4 | 445
Cancer 4 | 2,499
Mammary Neoplasms 4 | 425
adult high grade glioma 4 | 3,801
aldosterone-producing adenoma 4 | 665
astrocytoma 4 | 1,146
atypical teratoid / rhabdoid tumor 4 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
juvenile dermatomyositis 4 | 1,187
lung carcinoma 4 | 2,843
Carcinoma, Pancreatic Ductal 3 | 20
Colonic Neoplasms 3 | 142
Duchenne muscular dystrophy 3 | 601
Liver disease 3 | 237
Rheumatoid arthritis 3 | 1,191
Uterine Cervical Neoplasm 3 | 25
Uterine Cervical Neoplasms 3 | 26
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
astrocytic glioma 3 | 2,597
group 4 medulloblastoma 3 | 1,855
invasive ductal carcinoma 3 | 2,951
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
Adenoid Cystic Carcinoma 2 | 99
Brachydactyly 2 | 156
Carcinoma, Adenoid Cystic 2 | 99
Carcinoma, Non-Small-Cell Lung 2 | 107
Carcinoma, Squamous Cell 2 | 110
Cataract 2 | 297
Cell Transformation, Neoplastic 2 | 97
Congenital hereditary endothelial dystrophy of cornea 2 | 8
Enophthalmos 2 | 75
Failure to gain weight 2 | 365
Heart disease 2 | 306
Hypersensitivity reaction type II disease 2 | 253
Immune system cancer 2 | 140
Infantile onset 2 | 238
Intellectual disability 2 | 1,016
Kidney disease 2 | 430
Lens Opacities 2 | 231
Leukemia, T-Cell 2 | 5
Liver Cirrhosis 2 | 181
Lung Neoplasms 2 | 232
Lymphoid leukemia 2 | 160
Multiple myeloma 2 | 1,332
Neoplastic Cell Transformation 2 | 89
Nervous System Diseases 2 | 53
Orbital separation excessive 2 | 244
Pediatric failure to thrive 2 | 365
Pick disease 2 | 1,894
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2 | 25
Prostatic Neoplasms 2 | 495
Short distal phalanges 2 | 50
Strabismus 2 | 270
Sunken eyes 2 | 63
Tetralogy of Fallot 2 | 63
Waldenstrons macroglobulinemia 2 | 765
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
inflammatory breast cancer 2 | 286
interstitial cystitis 2 | 2,312
lung adenocarcinoma 2 | 2,716
malignant mesothelioma 2 | 3,232
nervous system disorder 2 | 53
non-small cell lung carcinoma 2 | 317
pediatric high grade glioma 2 | 1,064
primary pancreatic ductal adenocarcinoma 2 | 1,109
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Acrocallosal syndrome 1 | 12
Coughing 1 | 25
Gingivitis 1 | 29
Idiopathic pulmonary arterial hypertension 1 | 40
Lymphoma, T-Cell 1 | 13
Primary ovarian failure 1 | 5
Skin Neoplasms 1 | 69
T-Cell Lymphoma 1 | 13
Upper respiratory tract disease 1 | 15
Urethral atrophy 1 | 4

Tissue

Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Blood and immune system 12 | 16,909
Cardiovascular System 12 | 15,192
Digestive Tract 12 | 17,369
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678
Liver and Pancreas 11 | 16,750

Target Family

Non-IDG 7 | 12,091
Transcription Factor 3 | 1,400
Kinase 2 | 634
Nuclear Receptor 1 | 48

GO Process

negative regulation of stem ce... 13 | 13
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Steroid hormone receptor ERR2 ESRRB Tchem Nuclear Receptor -1.95523 86.9 173
Heterogeneous nuclear ribonucleoprotein U HNRNPU Tbio Non-IDG -2.33813 207.8 169
Cyclin-dependent kinase 12 CDK12 Tchem Kinase -1.38476 29.4 157
Transcription factor HES-5 HES5 Tbio Transcription Factor -2.08501 97.6 139
mRNA decay activator protein ZFP36L2 ZFP36L2 Tbio Non-IDG -1.54477 30.6 140
Protein LBH LBH Tbio Non-IDG -0.40369 3.27 57
Tripartite motif-containing protein 6 TRIM6 Tbio Non-IDG 0.60 0.75 86
Transcription factor HES-1 HES1 Tbio Transcription Factor -1.77409 55.5 444
Protein jagged-1 JAG1 Tbio Non-IDG -3.09216 1190.8 473
Histone H1oo H1FOO Tbio Non-IDG -1.48386 31.5 137