Development Level

Tbio 12 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal hindbrain development 1 | 16
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal limb morphology 1 | 13
abnormal liver size 1 | 5
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal stomach morphology 1 | 10
abnormal tail morphology 1 | 25
abnormal vibrissa morphology 1 | 25
cataract 1 | 92
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 126
decreased mean corpuscular vol... 1 | 79
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
hemorrhage 1 | 23
increased bone mineral density 1 | 72
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased mean corpuscular hem... 1 | 36
pale liver 1 | 6
pale yolk sac 1 | 25
pallor 1 | 34
preweaning lethality, incomple... 1 | 499
respiratory system phenotype 1 | 2

Disease

Carcinoma 9 | 11,493
Cancer 7 | 2,499
ovarian cancer 7 | 8,520
osteosarcoma 6 | 7,950
Cleft Palate 5 | 271
Cardiac Arrhythmia 4 | 103
Cardiac conduction abnormalities 4 | 78
Conduction disorder of the heart 4 | 79
EKG abnormalities 4 | 78
Electrocardiogram abnormal 4 | 81
Electrocardiogram change 4 | 78
Fatigue 4 | 182
Uranostaphyloschisis 4 | 167
diabetes mellitus 4 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
Abnormality of the urinary system 3 | 21
Anemia 3 | 365
Anemia, Diamond-Blackfan 3 | 16
Anemia, Macrocytic 3 | 18
Delayed Puberty 3 | 97
Diamond-Blackfan anemia 3 | 31
Hand deformities 3 | 32
Intermittent migraine headaches 3 | 68
Migraine Disorders 3 | 76
Pallor 3 | 40
atypical teratoid / rhabdoid tumor 3 | 5,112
genital abnormal 3 | 17
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
malignant mesothelioma 3 | 3,232
medulloblastoma, large-cell 3 | 6,241
psoriasis 3 | 6,694
reproductive system abnormality 3 | 17
tuberculosis 3 | 2,010
Acquired scoliosis 2 | 281
Adult onset 2 | 82
Alzheimer Disease 2 | 83
Alzheimer's disease 2 | 658
Autosomal recessive predisposition 2 | 1,442
Breast Neoplasms 2 | 445
Breast cancer 2 | 3,578
Cardiomyopathy 2 | 116
Cleft Lip 2 | 141
Congestive heart failure 2 | 113
Curvature of spine 2 | 282
Depressive disorder 2 | 409
Dystonia 2 | 164
Gait abnormality 2 | 135
Glaucoma 2 | 239
Heart failure 2 | 162
Liver carcinoma 2 | 240
Mammary Neoplasms 2 | 425
Mean cell volume increased 2 | 5
Melanocytic nevus 2 | 43
Mental Depression 2 | 333
Multiple Sclerosis 2 | 540
Multiple myeloma 2 | 1,332
Myoclonus 2 | 74
Neurodegenerative disease 2 | 414
Osteoporosis 2 | 363
Parkinson's disease 2 | 392
Schizophrenia 2 | 1,160
Splenomegaly 2 | 190
cutaneous lupus erythematosus 2 | 1,057
glioblastoma 2 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
juvenile dermatomyositis 2 | 1,187
medulloblastoma 2 | 720
mucosa-associated lymphoid tissue lymphoma 2 | 484
sonic hedgehog group medulloblastoma 2 | 467
ulcerative colitis 2 | 1,819
Abnormal brain FDG positron emission tomography 1 | 9
Adenocarcinoma in situ 1 | 15
Alcohol abuse 1 | 50
Asphyxia neonatorum 1 | 11
Behavioral variant of frontotemporal dementia 1 | 8
Birth Weight 1 | 13
Cervicitis 1 | 6
Difficulty making arithmetical calculations 1 | 8
EEG with continuous slow activity 1 | 7
Favorable response to levodopa 1 | 6
Frontotemporal cerebral atrophy 1 | 8
Hyperorality 1 | 7
Iron deficiency anemia 1 | 12
Learning Disorders 1 | 29
Melanoma, Cutaneous Malignant, Susceptibility To, 2 1 | 2
Melanoma-Astrocytoma Syndrome 1 | 2
Melanoma-Pancreatic Cancer Syndrome 1 | 2
Micronuclei, Chromosome-Defective 1 | 25
Myeloma, Multiple 1 | 6
Neoplasms, Second Primary 1 | 6
Otomycosis 1 | 2
Peripheral Nervous System Diseases 1 | 52
Poisoning 1 | 16
Repeated speech 1 | 9
Restrictive behavior 1 | 7
Restrictive behavior, interests, and activities 1 | 7
Urinary system cancer 1 | 4
menstrual periods stopped for over 6 months 1 | 13
pancreatic ductal carcinoma 1 | 11
skin melanoma 1 | 14

Tissue

Blood and immune system 14 | 16,909
Digestive Tract 14 | 17,369
Endocrine System 14 | 18,159
Female tissues 14 | 17,400
Liver and Pancreas 14 | 16,750
Nervous System 14 | 16,725
Respiratory system 14 | 16,393
Urinary Tract 14 | 16,678
Male tissues 13 | 17,142
Skin and soft tissues 13 | 17,230
Cardiovascular System 12 | 15,192

Target Family

Non-IDG 11 | 12,091
Enzyme 2 | 4,145
Kinase 1 | 634

GO Process

negative regulation of protein... 14 | 14
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase TRIM39 TRIM39 Tbio Enzyme -1.24729 16.2 194
Small glutamine-rich tetratricopeptide repeat-containing protein alpha SGTA Tbio Non-IDG -2.39136 244.6 191
60S ribosomal protein L23 RPL23 Tbio Non-IDG -1.57812 38.1 118
Presenilin-1 PSEN1 Tchem Enzyme -3.53128 3394.7 677
Phosducin-like protein 3 PDCL3 Tbio Non-IDG -1.80125 55.7 114
60S ribosomal protein L5 RPL5 Tbio Non-IDG -2.02831 78.3 228
Transcription initiation factor TFIID subunit 1 TAF1 Tchem Kinase -2.64215 426.1 228
Suppressor of fused homolog SUFU Tbio Non-IDG -2.33544 208.6 168
40S ribosomal protein S7 RPS7 Tbio Non-IDG -1.84836 69.5 112
Protein PML PML Tbio Non-IDG -2.63785 373.8 470