Development Level

Tbio 26 | 11,445
Tchem 12 | 1,598
Tclin 3 | 613
Tdark 3 | 6,588

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

decreased total body fat amoun... 3 | 207
preweaning lethality, incomple... 3 | 499
increased circulating alkaline... 2 | 122
increased grip strength 2 | 41
increased mean corpuscular hem... 2 | 96
increased or absent threshold ... 2 | 101
preweaning lethality, complete... 2 | 979
thrombocytopenia 2 | 56
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal eyelid morphology 1 | 7
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal head size 1 | 6
abnormal snout morphology 1 | 23
abnormal vertebral arch morpho... 1 | 9
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
cleft palate 1 | 8
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased prepulse inhibition 1 | 82
embryonic lethality prior to t... 1 | 278
facial cleft 1 | 3
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating phosphat... 1 | 26
increased startle reflex 1 | 112
mammalian phenotype 1 | 17
prenatal lethality prior to he... 1 | 87
prolonged PQ interval 1 | 5
short tibia 1 | 97
small adrenal glands 1 | 16

Disease

ovarian cancer 30 | 8,520
Carcinoma 24 | 11,493
osteosarcoma 24 | 7,950
medulloblastoma, large-cell 23 | 6,241
psoriasis 23 | 6,694
Cancer 22 | 2,499
atypical teratoid / rhabdoid tumor 21 | 5,112
glioblastoma 19 | 5,792
lung cancer 18 | 4,740
adult high grade glioma 14 | 3,801
malignant mesothelioma 12 | 3,232
non-small cell lung cancer 12 | 2,890
diabetes mellitus 11 | 1,728
group 3 medulloblastoma 11 | 4,104
Astrocytoma, Pilocytic 10 | 3,081
Multiple myeloma 10 | 1,332
ependymoma 10 | 4,679
lung carcinoma 10 | 2,843
subependymal giant cell astrocytoma 10 | 2,287
Breast cancer 9 | 3,578
invasive ductal carcinoma 9 | 2,951
lung adenocarcinoma 9 | 2,716
oligodendroglioma 9 | 2,850
tuberculosis 9 | 2,010
Schizophrenia 8 | 1,160
astrocytic glioma 8 | 2,597
colon cancer 8 | 1,478
ulcerative colitis 8 | 1,819
Alzheimer's disease 7 | 658
Waldenstrons macroglobulinemia 7 | 765
astrocytoma 7 | 1,146
dermatomyositis 7 | 966
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
juvenile dermatomyositis 7 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
primitive neuroectodermal tumor 7 | 3,035
Bipolar Disorder 6 | 666
Liver Cirrhosis, Experimental 6 | 769
Toxic encephalopathy 6 | 141
cystic fibrosis 6 | 1,696
interstitial cystitis 6 | 2,312
pancreatic cancer 6 | 2,398
Autosomal recessive predisposition 5 | 1,442
Intellectual disability 5 | 1,016
Pick disease 5 | 1,894
Rheumatoid arthritis 5 | 1,191
cutaneous lupus erythematosus 5 | 1,057
esophageal adenocarcinoma 5 | 737
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
Amyotrophic lateral sclerosis 4 | 451
Brain disease 4 | 96
Chronic Lymphocytic Leukemia 4 | 262
Crohn's disease 4 | 321
Depressive disorder 4 | 409
Kidney cancer 4 | 2,613
Multiple Sclerosis 4 | 540
Neurodegenerative disease 4 | 414
Obesity 4 | 678
Parkinson's disease 4 | 392
active Crohn's disease 4 | 922
acute quadriplegic myopathy 4 | 1,158
breast carcinoma 4 | 1,638
ductal carcinoma in situ 4 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
medulloblastoma 4 | 720
pituitary cancer 4 | 1,972
spina bifida 4 | 1,074
Anemia 3 | 365
Cocaine Dependence 3 | 51
Colorectal Neoplasms 3 | 243
Connective tissue disease 3 | 62
Down syndrome 3 | 499
Hypertension 3 | 396
Hypertensive disease 3 | 292
Major Depressive Disorder 3 | 301
Mental Depression 3 | 333
Ovarian Neoplasms 3 | 102
Stomach Neoplasms 3 | 300
Systemic lupus erythematosus 3 | 194
Unipolar Depression 3 | 250
Vascular disease 3 | 319
chronic rhinosinusitis 3 | 512
gastric cancer 3 | 459
nasopharyngeal carcinoma 3 | 1,058
primary pancreatic ductal adenocarcinoma 3 | 1,109
Atherosclerosis 2 | 291
Attention deficit hyperactivity disorder 2 | 278
Cerebrovascular disease 2 | 238
Duchenne muscular dystrophy 2 | 601
Hepatomegaly 2 | 285
Inflammatory bowel disease 2 | 151
Kidney disease 2 | 430
Myocardial Ischemia 2 | 169
acute myeloid leukemia 2 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
fibroadenoma 2 | 559
hepatocellular carcinoma 2 | 547
progressive supranuclear palsy 2 | 676
urothelial carcinoma 2 | 318

Tissue

Digestive Tract 43 | 17,369
Endocrine System 43 | 18,159
Male tissues 43 | 17,142
Nervous System 43 | 16,725
Skin and soft tissues 43 | 17,230
Blood and immune system 42 | 16,909
Female tissues 42 | 17,400
Liver and Pancreas 42 | 16,750
Cardiovascular System 41 | 15,192
Respiratory system 41 | 16,393
Urinary Tract 41 | 16,678

Target Family

Non-IDG 26 | 12,091
Enzyme 7 | 4,145
Kinase 5 | 634
Transcription Factor 3 | 1,400
Epigenetic 2 | 242
GPCR 1 | 408

GO Process

negative regulation of protein... 44 | 44
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone deacetylase 8 HDAC8 Tclin Epigenetic -2.41838 263.5 487
Guanine nucleotide-binding protein-like 3-like protein GNL3L Tbio Non-IDG -0.65739 5.74 141
Putative peripheral benzodiazepine receptor-related protein TSPO Tchem Non-IDG -3.08695 2284.2 212
Calcineurin B homologous protein 1 CHP1 Tbio Non-IDG -1.63966 41.9 162
Nucleoredoxin NXN Tbio Non-IDG -2.54390 345.4 96
E3 UFM1-protein ligase 1 UFL1 Tbio Enzyme -1.20721 16.5 85
40S ribosomal protein S3 RPS3 Tbio Non-IDG -2.19489 157.7 218
NEDD4-binding protein 1 N4BP1 Tdark Non-IDG -0.70274 3.55 91
Heat shock 70 kDa protein 1B HSPA1B Tbio Non-IDG -1.61862 0.00000 60
Heat shock 70 kDa protein 1A HSPA1B Tchem Non-IDG -3.10995 0.00000 1174