Development Level

Tbio 46 | 11,445
Tchem 16 | 1,598
Tclin 4 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to t... 3 | 278
increased circulating alkaline... 3 | 122
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal coat-hair pigmentatio... 2 | 64
decreased blood urea nitrogen ... 2 | 51
decreased body length 2 | 101
decreased grip strength 2 | 116
decreased mean corpuscular vol... 2 | 79
decreased total body fat amoun... 2 | 207
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
hyperactivity 2 | 148
impaired glucose tolerance 2 | 75
increased fasted circulating g... 2 | 76
increased lean body mass 2 | 172
increased total body fat amoun... 2 | 134
thrombocytopenia 2 | 56
abnormal QT variability 1 | 10
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal lung morphology 1 | 26
abnormal maxilla morphology 1 | 17
abnormal rib morphology 1 | 10
abnormal urinary bladder morph... 1 | 11
absent startle reflex 1 | 24
absent vibrissae 1 | 12
cataract 1 | 92
decreased basophil cell number 1 | 16
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating choleste... 1 | 66
increased circulating phosphat... 1 | 26
increased circulating thyroxin... 1 | 7
increased erythrocyte cell num... 1 | 39
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
prolonged PR interval 1 | 15
short tibia 1 | 97
urinary bladder obstruction 1 | 4
vertebral fusion 1 | 23

Disease

Carcinoma 49 | 11,493
ovarian cancer 40 | 8,520
glioblastoma 38 | 5,792
osteosarcoma 38 | 7,950
medulloblastoma, large-cell 32 | 6,241
lung cancer 30 | 4,740
psoriasis 27 | 6,694
atypical teratoid / rhabdoid tumor 23 | 5,112
Cancer 22 | 2,499
group 3 medulloblastoma 21 | 4,104
lung adenocarcinoma 21 | 2,716
ependymoma 20 | 4,679
non-small cell lung cancer 20 | 2,890
pancreatic cancer 20 | 2,398
Breast cancer 19 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,955
invasive ductal carcinoma 19 | 2,951
malignant mesothelioma 19 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
lung carcinoma 17 | 2,843
adult high grade glioma 16 | 3,801
Astrocytoma, Pilocytic 15 | 3,081
Pick disease 15 | 1,894
breast carcinoma 15 | 1,638
diabetes mellitus 15 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
Kidney cancer 14 | 2,613
colon cancer 14 | 1,478
astrocytic glioma 13 | 2,597
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
subependymal giant cell astrocytoma 13 | 2,287
tuberculosis 13 | 2,010
cystic fibrosis 12 | 1,696
oligodendroglioma 12 | 2,850
ulcerative colitis 12 | 1,819
Alzheimer's disease 11 | 658
Schizophrenia 11 | 1,160
adrenocortical carcinoma 11 | 1,428
pituitary cancer 11 | 1,972
Autistic Disorder 10 | 364
primary pancreatic ductal adenocarcinoma 10 | 1,109
primitive neuroectodermal tumor 10 | 3,035
Melanoma 9 | 711
Parkinson's disease 9 | 392
juvenile dermatomyositis 9 | 1,187
progressive supranuclear palsy 9 | 676
Neurodegenerative disease 8 | 414
Prostatic Neoplasms 8 | 495
gastric carcinoma 8 | 807
pediatric high grade glioma 8 | 1,064
Atopic dermatitis 7 | 952
Bipolar Disorder 7 | 666
Duchenne muscular dystrophy 7 | 601
Intellectual disability 7 | 1,016
Rheumatoid arthritis 7 | 1,191
Toxic encephalopathy 7 | 141
active Crohn's disease 7 | 922
acute myeloid leukemia 7 | 783
astrocytoma 7 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
dermatomyositis 7 | 966
group 4 medulloblastoma 7 | 1,855
interstitial cystitis 7 | 2,312
nasopharyngeal carcinoma 7 | 1,058
Autosomal recessive predisposition 6 | 1,442
Dementia 6 | 175
Multiple system atrophy 6 | 29
Nerve Degeneration 6 | 121
Skin cancer 6 | 469
acute quadriplegic myopathy 6 | 1,158
cutaneous lupus erythematosus 6 | 1,057
ductal carcinoma in situ 6 | 1,745
Amyotrophic lateral sclerosis 5 | 451
Carcinoma, Hepatocellular 5 | 228
Depressive disorder 5 | 409
Endometriosis 5 | 540
Epilepsy 5 | 792
Hypertension 5 | 396
Hypertensive disease 5 | 292
Kidney disease 5 | 430
Liver Cirrhosis, Experimental 5 | 769
Liver carcinoma 5 | 240
Lung Neoplasms 5 | 232
Multiple myeloma 5 | 1,332
Obesity 5 | 678
Osteoporosis 5 | 363
Vascular disease 5 | 319
active ulcerative colitis 5 | 764
spina bifida 5 | 1,074
Brain disease 4 | 96
Crohn's disease 4 | 321
Endometrial cancer 4 | 311
Huntington's disease 4 | 76
Major Depressive Disorder 4 | 301
Myopathy 4 | 185
Parkinson Disease 4 | 64
Thrombocytopenia 4 | 197
limb girdle muscular dystrophy 2A 4 | 213
posterior fossa group B ependymoma 4 | 416
sarcoidosis 4 | 370

Tissue

Blood and immune system 66 | 16,909
Liver and Pancreas 66 | 16,750
Digestive Tract 65 | 17,369
Endocrine System 65 | 18,159
Female tissues 65 | 17,400
Male tissues 65 | 17,142
Skin and soft tissues 65 | 17,230
Nervous System 64 | 16,725
Urinary Tract 64 | 16,678
Respiratory system 62 | 16,393
Cardiovascular System 59 | 15,192

Target Family

Non-IDG 36 | 12,091
Enzyme 17 | 4,145
Kinase 7 | 634
Transcription Factor 3 | 1,400
GPCR 2 | 408
Ion Channel 1 | 344

GO Process

negative regulation of protein... 66 | 66
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CD109 antigen CD109 Tbio Non-IDG -1.85817 77.8 239
Calcium and integrin-binding protein 1 CIB1 Tbio Non-IDG -2.08897 121.1 264
Cactin CACTIN Tbio Non-IDG -1.26544 19.0 50
Calcineurin B homologous protein 1 CHP1 Tbio Non-IDG -1.63966 41.9 162
CTD small phosphatase-like protein CTDSPL Tbio Enzyme -2.17507 152.7 141
Paired box protein Pax-6 PAX6 Tbio Transcription Factor -3.16650 1458.6 570
Telomeric repeat-binding factor 2-interacting protein 1 TERF2IP Tchem Non-IDG -0.75509 5.75 308
Endoribonuclease ZC3H12A ZC3H12A Tbio Enzyme -1.81028 77.8 134
Tryptophan--tRNA ligase, cytoplasmic WARS Tbio Enzyme -2.74520 518.6 163
Neuronal acetylcholine receptor subunit alpha-7 CHRFAM7A Tchem Ion Channel -1.81173 87.7 226