Development Level

Tbio 8 | 11,445

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating magnesiu... 1 | 13
decreased circulating total pr... 1 | 49
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating thyroxin... 1 | 7
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased lean body mass 1 | 172
pale yolk sac 1 | 25
pallor 1 | 34

Disease

Carcinoma 5 | 11,493
lung adenocarcinoma 5 | 2,716
oligodendroglioma 5 | 2,850
ovarian cancer 5 | 8,520
atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
acute quadriplegic myopathy 3 | 1,158
adult high grade glioma 3 | 3,801
ependymoma 3 | 4,679
invasive ductal carcinoma 3 | 2,951
juvenile dermatomyositis 3 | 1,187
lung carcinoma 3 | 2,843
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
primitive neuroectodermal tumor 3 | 3,035
Amyotrophic lateral sclerosis 2 | 451
Cancer 2 | 2,499
Duchenne muscular dystrophy 2 | 601
Multiple myeloma 2 | 1,332
Waldenstrons macroglobulinemia 2 | 765
acute myeloid leukemia 2 | 783
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
gastric carcinoma 2 | 807
group 3 medulloblastoma 2 | 4,104
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung cancer 2 | 4,740
mucosa-associated lymphoid tissue lymphoma 2 | 484
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,109
psoriasis 2 | 6,694
tuberculosis 2 | 2,010
AICARDI-GOUTIERES SYNDROME 1 1 | 5
Acute Promyelocytic Leukemia 1 | 40
Adenocarcinoma of lung 1 | 142
Aicardi-Goutieres syndrome 1 | 19
Alzheimer's disease 1 | 658
Arhinencephaly 1 | 5
Astrocytoma, Pilocytic 1 | 3,081
Attention deficit hyperactivity disorder 1 | 278
Bipolar Disorder 1 | 666
Breast Neoplasms 1 | 445
Carcinoma, Non-Small-Cell Lung 1 | 107
Chronic obstructive pulmonary disease 1 | 184
Coloboma of eyelid 1 | 15
Contact Dermatitis 1 | 81
Disease Models, Animal 1 | 155
Dowling-Degos disease 1 | 7
Drug psychosis 1 | 7
Dyschromatosis symmetrica hereditaria 1 | 4
Dystonia Musculorum Deformans 1 | 5
Glomerulonephritis, IGA 1 | 34
Hemiplegia and hemiparesis 1 | 38
IGA Glomerulonephritis 1 | 50
Infantile onset 1 | 238
Inflammation 1 | 120
Leukemia, Acute Myeloid 1 | 17
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Leukemia, Promyelocytic, Acute 1 | 36
Loss of ability to walk 1 | 3
Loss of speech 1 | 16
Lymphoma, Primary Cutaneous Anaplastic Large Cell 1 | 2
Lymphomatoid Papulosis 1 | 2
Muscle Rigidity 1 | 49
Muscle Spasticity 1 | 195
Pain agnosia 1 | 104
Parkinson's disease 1 | 392
Pick disease 1 | 1,894
Polycystic ovary syndrome 1 | 360
Porencephaly 1 | 20
Profound Mental Retardation 1 | 31
Profound intellectual disabilities 1 | 31
Psychotic Disorders 1 | 151
Schizophrenia 1 | 1,160
Spindle cell hemangioma 1 | 16
Stomach Neoplasms 1 | 300
Striatonigral Degeneration, Infantile 1 | 4
Toxic encephalopathy 1 | 141
Tremor 1 | 113
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
adrenocortical carcinoma 1 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
breast carcinoma 1 | 1,638
colon cancer 1 | 1,478
cystic fibrosis 1 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
limb girdle muscular dystrophy 2A 1 | 213
non-small cell lung carcinoma 1 | 317
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pediatric high grade glioma 1 | 1,064
progressive supranuclear palsy 1 | 676
sonic hedgehog group medulloblastoma 1 | 467
subependymal giant cell astrocytoma 1 | 2,287

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Enzyme 5 | 4,145
Non-IDG 3 | 12,091

GO Process

negative regulation of protein... 8 | 8
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual specificity protein phosphatase 26 DUSP26 Tbio Enzyme -2.81752 661.7 128
Double-stranded RNA-specific editase 1 ADARB1 Tbio Enzyme -2.08959 118.0 103
Protein phosphatase 1F PPM1F Tbio Enzyme -1.53852 37.0 236
Double-stranded RNA-specific adenosine deaminase ADAR Tbio Enzyme -2.87338 784.2 197
Coronin-1C CORO1C Tbio Non-IDG -1.47050 32.6 211
Dual specificity protein phosphatase 10 DUSP10 Tbio Enzyme -1.51719 38.2 270
Nucleophosmin NPM1 Tbio Non-IDG -3.12496 1315.8 912
CDK5 regulatory subunit-associated protein 3 CDK5RAP3 Tbio Non-IDG -1.31044 22.6 145