Development Level

Tbio 33 | 11,445
Tchem 6 | 1,598
Tclin 4 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal embryo size 1 | 220
abnormal heart left ventricle ... 1 | 16
abnormal locomotor behavior 1 | 24
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased body weight 1 | 161
decreased circulating alkaline... 1 | 46
decreased circulating iron lev... 1 | 32
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
impaired glucose tolerance 1 | 75
increased IgG2b level 1 | 1
increased body weight 1 | 25
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased prepulse inhibition 1 | 32
thrombocytopenia 1 | 56

Disease

Carcinoma 30 | 11,493
ovarian cancer 24 | 8,520
Cancer 20 | 2,499
osteosarcoma 20 | 7,950
psoriasis 20 | 6,694
medulloblastoma, large-cell 19 | 6,241
lung cancer 16 | 4,740
ependymoma 12 | 4,679
atypical teratoid / rhabdoid tumor 11 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
Breast cancer 10 | 3,578
Kidney cancer 10 | 2,613
glioblastoma 10 | 5,792
lung adenocarcinoma 10 | 2,716
non-small cell lung cancer 10 | 2,890
oligodendroglioma 10 | 2,850
invasive ductal carcinoma 9 | 2,951
malignant mesothelioma 9 | 3,232
Obesity 8 | 678
breast carcinoma 8 | 1,638
group 3 medulloblastoma 8 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
Alzheimer's disease 7 | 658
Bipolar Disorder 7 | 666
Cataract 7 | 297
Schizophrenia 7 | 1,160
diabetes mellitus 7 | 1,728
group 4 medulloblastoma 7 | 1,855
interstitial cystitis 7 | 2,312
pancreatic cancer 7 | 2,398
subependymal giant cell astrocytoma 7 | 2,287
ulcerative colitis 7 | 1,819
Breast Neoplasms 6 | 445
Mammary Neoplasms 6 | 425
Myopathy 6 | 185
Pick disease 6 | 1,894
Seizures 6 | 596
Vascular disease 6 | 319
adrenocortical carcinoma 6 | 1,428
adult high grade glioma 6 | 3,801
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
pituitary cancer 6 | 1,972
Autistic Disorder 5 | 364
Autosomal recessive predisposition 5 | 1,442
Intellectual disability 5 | 1,016
Mental Depression 5 | 333
Mood Disorders 5 | 184
Parkinson's disease 5 | 392
Skin cancer 5 | 469
astrocytic glioma 5 | 2,597
astrocytoma 5 | 1,146
colon cancer 5 | 1,478
ductal carcinoma in situ 5 | 1,745
lung carcinoma 5 | 2,843
nasopharyngeal carcinoma 5 | 1,058
spina bifida 5 | 1,074
tuberculosis 5 | 2,010
Amphetamine-Related Disorders 4 | 74
Big calvaria 4 | 147
Cognitive delay 4 | 608
Colorectal Neoplasms 4 | 243
Depressive disorder 4 | 409
Dull intelligence 4 | 645
Epilepsy 4 | 792
Global developmental delay 4 | 608
Increased head circumference 4 | 147
Increased size of cranium 4 | 147
Increased size of skull 4 | 147
Liver cancer 4 | 604
Low intelligence 4 | 645
Melanoma 4 | 711
Mental Retardation 4 | 645
Mental and motor retardation 4 | 608
Mental deficiency 4 | 645
Multiple, subcutaneous nodules 4 | 53
Myopia 4 | 176
Poor school performance 4 | 645
Prostatic Neoplasms 4 | 495
Pulmonary embolism 4 | 55
Renal Cell Carcinoma 4 | 214
Squamous cell carcinoma 4 | 129
Subcutaneous nodule 4 | 53
Waldenstrons macroglobulinemia 4 | 765
cystic fibrosis 4 | 1,696
fibroadenoma 4 | 559
juvenile dermatomyositis 4 | 1,187
non primary Sjogren syndrome sicca 4 | 891
Acquired scoliosis 3 | 281
Atopic dermatitis 3 | 952
Attention deficit hyperactivity disorder 3 | 278
Byzanthine arch palate 3 | 194
Curvature of spine 3 | 282
Down syndrome 3 | 499
Endometrial cancer 3 | 311
Hypothyroidism 3 | 122
Kidney disease 3 | 430
active ulcerative colitis 3 | 764
chronic rhinosinusitis 3 | 512
urothelial carcinoma 3 | 318

Tissue

Endocrine System 44 | 18,159
Digestive Tract 43 | 17,369
Female tissues 42 | 17,400
Liver and Pancreas 42 | 16,750
Male tissues 42 | 17,142
Respiratory system 42 | 16,393
Skin and soft tissues 42 | 17,230
Blood and immune system 41 | 16,909
Urinary Tract 41 | 16,678
Cardiovascular System 40 | 15,192
Nervous System 40 | 16,725

Target Family

Non-IDG 19 | 12,091
Enzyme 15 | 4,145
GPCR 3 | 408
Kinase 3 | 634
Transcription Factor 2 | 1,400
Epigenetic 1 | 242
Transporter 1 | 473

GO Process

negative regulation of protein... 44 | 44
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-crystallin A3 CRYBA1 Tbio Non-IDG -1.45158 27.2 133
Pleckstrin homology-like domain family A member 3 PHLDA3 Tbio Non-IDG -0.83900 8.89 101
Calcium and integrin-binding protein 1 CIB1 Tbio Non-IDG -2.08897 121.1 264
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 MAGI2 Tbio Enzyme -1.54170 33.0 178
Krueppel-like factor 4 KLF4 Tbio Transcription Factor -2.89447 774.1 686
Rap guanine nucleotide exchange factor 1 RAPGEF1 Tbio Non-IDG -2.41980 281.2 167
B-cell scaffold protein with ankyrin repeats BANK1 Tbio Non-IDG -1.44172 29.5 90
Receptor-type tyrosine-protein phosphatase eta PTPRJ Tbio Enzyme -1.98955 114.2 298
PH domain leucine-rich repeat-containing protein phosphatase 2 PHLPP2 Tbio Enzyme -1.37775 18.4 122
LEM domain-containing protein 2 LEMD2 Tdark Non-IDG -0.53782 3.95 95