Development Level

Tbio 42 | 11,651
Tchem 16 | 1,388
Tclin 5 | 612
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
abnormal retina morphology 2 | 71
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased startle reflex 2 | 112
thrombocytosis 2 | 27
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo turning 1 | 31
abnormal gait 1 | 69
abnormal iris pigmentation 1 | 4
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating glycerol... 1 | 16
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
hypoactivity 1 | 132
increased circulating bilirubi... 1 | 16
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased or absent threshold ... 1 | 101
limb grasping 1 | 41
prolonged ST segment 1 | 36
sclerocornea 1 | 2
small heart 1 | 10
small kidney 1 | 16
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small superior vagus ganglion 1 | 74

Disease

Carcinoma 40 | 11,493
osteosarcoma 32 | 7,950
ovarian cancer 28 | 8,520
psoriasis 27 | 6,694
Cancer 24 | 2,499
lung cancer 24 | 4,740
medulloblastoma, large-cell 24 | 6,241
group 3 medulloblastoma 23 | 4,104
glioblastoma 20 | 5,792
atypical teratoid / rhabdoid tumor 19 | 5,112
ependymoma 17 | 4,679
adult high grade glioma 16 | 3,801
invasive ductal carcinoma 16 | 2,951
malignant mesothelioma 16 | 3,232
Kidney cancer 15 | 2,613
non-small cell lung cancer 15 | 2,890
lung adenocarcinoma 14 | 2,716
Breast cancer 13 | 3,578
diabetes mellitus 13 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
pancreatic cancer 12 | 2,398
cutaneous lupus erythematosus 11 | 1,057
interstitial cystitis 11 | 2,312
primitive neuroectodermal tumor 11 | 3,035
Alzheimer's disease 10 | 658
Astrocytoma, Pilocytic 10 | 3,081
Schizophrenia 10 | 1,160
dermatomyositis 10 | 966
subependymal giant cell astrocytoma 10 | 2,287
Autosomal recessive predisposition 9 | 1,442
Pick disease 9 | 1,894
astrocytic glioma 9 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
lung carcinoma 9 | 2,843
oligodendroglioma 9 | 2,850
tuberculosis 9 | 2,010
group 4 medulloblastoma 8 | 1,855
juvenile dermatomyositis 8 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
ulcerative colitis 8 | 1,819
Multiple myeloma 7 | 1,332
cystic fibrosis 7 | 1,696
ductal carcinoma in situ 7 | 1,745
Depressive disorder 6 | 409
Hypertension 6 | 396
Kidney disease 6 | 430
Parkinson's disease 6 | 392
Prostatic Neoplasms 6 | 495
Waldenstrons macroglobulinemia 6 | 765
acute quadriplegic myopathy 6 | 1,158
breast carcinoma 6 | 1,638
spina bifida 6 | 1,074
Bipolar Disorder 5 | 666
Breast Neoplasms 5 | 445
Dementia 5 | 175
Diabetes Mellitus, Experimental 5 | 108
Endometriosis 5 | 540
Heart disease 5 | 306
Hepatomegaly 5 | 285
Hypertensive disease 5 | 292
Intellectual disability 5 | 1,016
Mammary Neoplasms 5 | 425
Neurodegenerative disease 5 | 414
Obesity 5 | 678
Rheumatoid arthritis 5 | 1,191
atypical teratoid/rhabdoid tumor 5 | 357
nasopharyngeal carcinoma 5 | 1,058
primary pancreatic ductal adenocarcinoma 5 | 1,109
Alzheimer Disease 4 | 83
Atherosclerosis 4 | 291
Atopic dermatitis 4 | 952
Chemical and Drug Induced Liver Injury 4 | 195
Cognitive delay 4 | 608
Dull intelligence 4 | 645
Global developmental delay 4 | 608
Low intelligence 4 | 645
Lung disease 4 | 142
Major Depressive Disorder 4 | 301
Melanoma 4 | 711
Mental Depression 4 | 333
Mental Retardation 4 | 645
Mental and motor retardation 4 | 608
Mental deficiency 4 | 645
Parkinsonian Disorders 4 | 56
Poor school performance 4 | 645
Skin cancer 4 | 469
Small head 4 | 374
Stomach Neoplasms 4 | 300
Toxic encephalopathy 4 | 141
active Crohn's disease 4 | 922
adrenocortical carcinoma 4 | 1,428
astrocytoma 4 | 1,146
esophageal adenocarcinoma 4 | 737
gastric carcinoma 4 | 807
pediatric high grade glioma 4 | 1,064
primary Sjogren syndrome 4 | 735
Duchenne muscular dystrophy 3 | 601
acute myeloid leukemia 3 | 783
mucosa-associated lymphoid tissue lymphoma 3 | 484

Tissue

Liver and Pancreas 63 | 16,750
Urinary Tract 63 | 16,678
Endocrine System 62 | 18,159
Female tissues 62 | 17,400
Skin and soft tissues 61 | 17,230
Digestive Tract 60 | 17,369
Male tissues 60 | 17,142
Nervous System 60 | 16,725
Blood and immune system 59 | 16,909
Respiratory system 59 | 16,393
Cardiovascular System 57 | 15,192

Target Family

Non-IDG 33 | 12,091
Enzyme 13 | 4,145
Kinase 11 | 634
Transcription Factor 3 | 1,400
Epigenetic 2 | 242
Ion Channel 1 | 344
Nuclear Receptor 1 | 48

GO Process

negative regulation of protein... 64 | 64
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Band 4.1-like protein 5 EPB41L5 Tbio Non-IDG -1.31136 21.8 109
E3 ubiquitin-protein ligase CHIP STUB1 Tbio Enzyme -2.96877 926.8 351
Golgin subfamily A member 2 GOLGA2 Tbio Non-IDG -1.95809 83.3 241
Disabled homolog 2 DAB2 Tbio Non-IDG -2.26146 184.8 239
Zinc finger protein ZFPM1 ZFPM1 Tbio Transcription Factor -2.52665 326.6 82
Dickkopf-related protein 1 DKK1 Tchem Non-IDG -2.79271 621.8 694
Platelet-derived growth factor subunit B PDGFB Tchem Non-IDG -3.27151 1795.5 434
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PPP1CA Tchem Enzyme -2.17010 139.0 378
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1 Tchem Enzyme -2.44422 522.8 528
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 WFIKKN1 Tbio Non-IDG -0.69215 6.16 30