Development Level

Tbio 7 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal retina morphology 1 | 71
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
decreased heart rate variabili... 1 | 13
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
edema 1 | 59
hypoactivity 1 | 132
increased or absent threshold ... 1 | 101
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 7 | 11,493
ovarian cancer 6 | 8,520
lung adenocarcinoma 5 | 2,716
lung cancer 5 | 4,740
medulloblastoma, large-cell 5 | 6,241
osteosarcoma 5 | 7,950
psoriasis 5 | 6,694
Hypertension 4 | 396
Hypertensive disease 4 | 292
atypical teratoid / rhabdoid tumor 4 | 5,112
Autosomal recessive predisposition 3 | 1,442
Kidney cancer 3 | 2,613
Long QT syndrome 3 | 39
Myopathy 3 | 185
acute quadriplegic myopathy 3 | 1,158
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
invasive ductal carcinoma 3 | 2,951
non-small cell lung cancer 3 | 2,890
Abnormality of metabolism/homeostasis 2 | 134
Adult onset 2 | 82
Astrocytoma, Pilocytic 2 | 3,081
Autistic Disorder 2 | 364
Breast cancer 2 | 3,578
Cardiomyopathy 2 | 116
Congenital Heart Defects 2 | 58
Disease of mental health 2 | 36
Endometriosis 2 | 540
Epilepsy 2 | 792
Heart disease 2 | 306
Parkinson's disease 2 | 392
Peutz-Jeghers syndrome 2 | 21
Seizures 2 | 596
Sudden death 2 | 16
Vascular disease 2 | 319
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
colon cancer 2 | 1,478
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
juvenile dermatomyositis 2 | 1,187
malignant mesothelioma 2 | 3,232
oligodendroglioma 2 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
spina bifida 2 | 1,074
ulcerative colitis 2 | 1,819
3p- syndrome 1 | 21
Abnormal lung lobation 1 | 10
Abnormality of the penis 1 | 7
Angioid streaks 1 | 11
Aqueductal Stenosis 1 | 5
Asymmetric chest 1 | 4
Birth length greater than 97th percentile 1 | 5
Calf muscle hypertrophy 1 | 9
Calvarial hyperostosis 1 | 5
Cardiomyopathy, Familial Hypertrophic, 1 (disorder) 1 | 7
Cerebral cavernous malformation 3 1 | 4
Chromosome 3, monosomy 3p25 1 | 3
Conjunctival hamartoma 1 | 7
Cowden syndrome 1 1 | 2
Endocardial Fibroelastosis 1 | 9
Enlarged cerebellum 1 | 3
Enlargement of calvarial bones 1 | 5
Exercise-induced muscle stiffness 1 | 3
Exostoses 1 | 11
Familial meningioma 1 | 4
Fibrous skin tumor of tuberous sclerosis 1 | 18
Gastrointestinal hamartomatous polyps 1 | 10
Gastrointestinal polyps 1 | 5
Hamartoma Syndrome, Multiple 1 | 10
Hamartomatous polyp 1 | 10
Hand polydactyly 1 | 11
Hashimoto Disease 1 | 4
Heterochromia iridis 1 | 9
Hyperkeratosis, generalized 1 | 14
Increased ossification of calvarial bones 1 | 5
Increased size of penis 1 | 7
Intestinal Polyposis 1 | 6
Intussusception 1 | 5
Leg Length Inequality 1 | 6
Lipomatosis 1 | 12
Macule 1 | 19
Meningioma, familial 1 | 6
Multiple lipomata 1 | 7
Multiple, subcutaneous nodules 1 | 53
Muscular Dystrophies, Limb-Girdle 1 | 7
Myalgia 1 | 54
NEVUS, EPIDERMAL (disorder) 1 | 5
Polyp of large intestine 1 | 8
Proteus syndrome 1 | 6
Pupillary abnormality 1 | 4
Rippling muscle disease 1 | 6
Shagreen patch 1 | 3
Subcutaneous lipomas 1 | 9
Subcutaneous nodule 1 | 53
Thyroid cancer, follicular 1 | 8
VACTERL Association With Hydrocephalus 1 | 3
Ventricular Tachycardia, Catecholaminergic Polymorphic, 1, With or Without Atrial Dysfunction And/Or Dilated Cardiomyopathy 1 | 4
congenital generalized lipodystrophy 1 | 10

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678
Nervous System 7 | 16,725

Target Family

Non-IDG 4 | 12,091
Enzyme 2 | 4,145
Kinase 2 | 634

GO Process

negative regulation of potassi... 8 | 8
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein kinase OSR1 OXSR1 Tbio Kinase -0.99836 9.44 355
STE20/SPS1-related proline-alanine-rich protein kinase STK39 Tbio Kinase -2.11714 148.9 575
Calcium-binding protein 39 CAB39 Tbio Non-IDG -1.61733 37.9 103
E3 ubiquitin-protein ligase NEDD4-like NEDD4L Tbio Enzyme -2.52486 353.9 144
Alpha-actinin-2 ACTN2 Tbio Non-IDG -1.89804 72.9 245
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN PTEN Tchem Enzyme -3.70874 5099.6 916
Calsequestrin-2 CASQ2 Tbio Non-IDG -1.93799 89.4 204
Caveolin-3 CAV3 Tbio Non-IDG -2.58501 381.9 200